DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31933 and CG32985

DIOPT Version :9

Sequence 1:	NP_722734.1	Gene:	CG31933 / 326176	FlyBaseID:	FBgn0051933	Length:	673	Species:	Drosophila melanogaster
Sequence 2:	NP_788013.2	Gene:	CG32985 / 326244	FlyBaseID:	FBgn0052985	Length:	644	Species:	Drosophila melanogaster

Alignment Length:	715	Identity:	177/715 - (24%)
Similarity:	313/715 - (43%)	Gaps:	135/715 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 SFRKLVLGVILTTII-LYAL---------LFLDTQCYETGGKIHNAFFVNTDGCRIIAMDVMNPT 59
            ||::|::..:..|:| |:::         ...|:|      ::...|:|.:..|:   |..:||.
  Fly     8 SFKRLIVSFLAVTLICLWSMNSSRVDENFSARDSQ------EVEKLFYVESGKCK---MRYVNPF 63

  Fly    60 IAKYTDWEWKDKRFYLKCPHQTWFRT----EVANGDWYLKLTRDIDRILQESDLTHDWQIKCYWF 120
            .|::.  :....:.::.|.:::...:    ::.| .:.|....::...|.||. |:|:  .|::.
  Fly    64 NAEFL--KINHPKAFIPCTNESDLISVHYDKILN-QYVLHTNEEVLHELSESK-TNDF--ACFYQ 122

  Fly   121 RIKIKGRWRAKIYGPTMFPLEYPYALK-----------VPKGLRHMRVKCLNTFTNKTLHDDAHF 174
            :|         |||.:   .|: |..|           ||..:..|.|:|......:.|..||..
  Fly   123 KI---------IYGQS---AEH-YDGKGVKTKISQNHLVPLDVEGMLVECRTADEMRVLQRDAFV 174

  Fly   175 FIQPPPEKLLKKPPATLKYWDGEKHSSGATSPI---SVMILGLDSVSHLNLLRQMPRTVRYMRQN 236
            |:|      .|.||..:|             |:   ||::.|:|:||..||.|.||....::: :
  Fly   175 FVQ------YKDPPQNVK-------------PVKKASVIMYGIDTVSRTNLRRMMPMVFEFLK-S 219

  Fly   237 MSQVEFWGFNKIGTNTYPNLIALLTGLSAAESEAYWVR---QKCMDNLPLIWKEFKRAGYNTSFA 298
            ....|..|:||:..|::||:.|:|||.|...:|.....   ..|:|.:|.|||:||:.||.|::|
  Fly   220 PGWYEMMGYNKVADNSFPNIFAMLTGFSPESAETQICNTDVDGCLDKIPFIWKDFKKDGYLTAYA 284

  Fly   299 EDMAIYSMFYFGKPGFKRPTTDNNLHDFMVDL----YINRQASSVSDTHCMGERAFMDILLEMND 359
            ||....:.|.:.||||....||.....|:..|    :|......|. .:|:|.|.....:.:...
  Fly   285 EDEEHSNTFNYAKPGFAVKPTDYYFRPFLTALENETFIQYCPGCVM-KYCLGRRLASSYIFDYCR 348

  Fly   360 RLLPHTQRY----PFFSFYWWANGFH-EFFNSPRLADGRFERLLRSLDDAGITNNTIIFFMSDHG 419
            :.:   ||:    |.:..:|..:..| :.|....:.....|.|| |.:..|:..:||:.|.||||
  Fly   349 QFM---QRFVADRPIWGMFWTNHYSHDDLFMLSAMQHKILEDLL-SFEKDGVFEHTIMIFFSDHG 409

  Fly   420 LRWGLFRSSFQGMIEDSQPFLSVLYPKWMRLKYPMAIKSLVGNAHSLVTTYDLHETLKHILEPSS 484
            .|:|....:.:..:|:..|.:.:..|.|.|.|||..:::|..|.:.|.:.:||:.|||||:....
  Fly   410 ARFGPLMYTKEAFLEERLPMMFIYLPPWFRKKYPRYVEALAQNQNRLSSNFDLYNTLKHIINIEG 474

  Fly   485 L-EDTSITQKTEELWKLKGSQTPRAVSLFLPIPPWRNCNTSHIPSKFCLCHKQIPIPESNRVVTK 548
            | |||.        |..   ..|:..|||.|:|..|:|:.:.||..:|.||....|.| ::...:
  Fly   475 LVEDTK--------WSY---DCPQCQSLFYPLPESRSCSEAAIPEAYCTCHNYEEIKE-DQGTWR 527

  Fly   549 SASIIIDYVNQLMVEY---PVCIPLQLDSIESAYFAAPQRDDDFYIEKGHKN----VYPEKGPFW 606
            .|::::|.:|:.:..:   .:|..|.|..|.|.......:|.|......|.:    |:.....|:
  Fly   528 LANLVVDRMNKYLHYHNLQNLCSNLTLRVINSTEVRMDDKDVDLANGMRHYHTKFQVHQNLAEFF 592

  Fly   607 KKQKYEDRDIVVRLKTKPGNAYFEGMTRRQGSKLSLVGEVVRVGGEGNRNNDCIDNPLLEPFCHC 671
            ....|:                      :|..:|.:..|::........:::|::|.:.:.:|.|
  Fly   593 ATVLYD----------------------KQTEELQMNVELISRTNMYGTDSECVNNKIQKLYCVC 635

Fly 672 671
Fly 636 635

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31933	NP_722734.1	DUF229	114..576	CDD:281053	139/491 (28%)
CG31933	NP_722734.1	ALP_like	208..483	CDD:293745	90/286 (31%)
CG32985	NP_788013.2	DUF229	72..554	CDD:308570	146/535 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466439
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D31599at6960
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10974
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.040