Protein Alignment CG31928 and REN

DIOPT Version :10

• Sequence 1: NP_722705.1
• Gene: CG31928 / 326175
• FlyBaseID: FBgn0051928
• Length: 418
• Species: Drosophila melanogaster
• Sequence 2: NP_000528.1
• Gene: REN / 5972
• HGNCID: 9958
• Length: 406
• Species: Homo sapiens
• Alignment Length: 373
• Identity: 119/373 - (31%)
• Similarity: 192/373 - (51%)
• Gaps: 29/373 - (7%)

  Fly    57 LKE------KLSPTSDLAISSVSVYQTTVSKENLINSHNTEYYVTAGFGTPKSQPVTLLVDTASA 115
            |||      :|.|.....:..:::..|| |...|.|..:|:||...|.||| .|...::.||.|:
Human    46 LKERGVDMARLGPEWSQPMKRLTLGNTT-SSVILTNYMDTQYYGEIGIGTP-PQTFKVVFDTGSS 108

  Fly   116 NLLVYSSEFVK--QSCLHHDGYNSSESQTYQANGSPFQIQFASQEILTGILSTDTFTLGDLVIKN 178
            |:.|.||:..:  .:|::|..:::|:|.:|:.||:...:::::..: :|.||.|..|:|.:.: .
Human   109 NVWVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTELTLRYSTGTV-SGFLSQDIITVGGITV-T 171

  Fly   179 QTFAEINSAPTDMCKRSNFDGIIGLGFSEIALNGVETPLDNILEQGLIDEPIFSLYVNRNASDA- 242
            |.|.|:...|......:.|||::|:||.|.|:..|....|||:.||::.|.:||.|.||::.::
Human   172 QMFGEVTEMPALPFMLAEFDGVVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDSENSQ 236

  Fly   243 SNGGVLLLGGSDPTLYSGCLTYVPVSKVGFWQITVGQVEIGSKK-LCSN-CQAIFDMGTSLIIVP 305
            |.||.::||||||..|.|...|:.:.|.|.|||.:..|.:||.. ||.: |.|:.|.|.|.|...
Human   237 SLGGQIVLGGSDPQHYEGNFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISGS 301

  Fly   306 CPALKIINKKLGIKET--DRKDGVYIIDCKKVSHLPKIVFNIGWKDFTLNPSDYILNYSGTCVSG 368
            ..:::.:.:.||.|:.  |     |::.|.:...||.|.|::|.|::||..:||:...|
Human   302 TSSIEKLMEALGAKKRLFD-----YVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQES------ 355

  Fly   369 FSSLSDCN-GTQTNDDSEDLNNIWVFGDVFFGAIFTLFDFGLKLVGMA 415
            :||...|. .....|........|..|..|....:|.||.....:|.|
Human   356 YSSKKLCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRRNNRIGFA 403

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31928	NP_722705.1	Asp	91..416	CDD:394983	108/333 (32%)
REN	NP_000528.1	A1_Propeptide	33..>51	CDD:462326	3/4 (75%)
		renin_like	78..405	CDD:133154	111/340 (33%)