DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG31928 and PGC

DIOPT Version :10

Sequence 1:NP_722705.1 Gene:CG31928 / 326175 FlyBaseID:FBgn0051928 Length:418 Species:Drosophila melanogaster
Sequence 2:NP_002621.1 Gene:PGC / 5225 HGNCID:8890 Length:388 Species:Homo sapiens


Alignment Length:389 Identity:124/389 - (31%)
Similarity:194/389 - (49%) Gaps:35/389 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly    34 QLKLHRETNHTK-ILSSFHNQKLRLKEKLSPTSDLAISSVSV-YQTTVSKENLINSHNTEYYVTA 96
            :.|..|||...| :|..|    || ..|..|........:|| |:.....:       ..|:...
Human    25 KFKSIRETMKEKGLLGEF----LR-THKYDPAWKYRFGDLSVTYEPMAYMD-------AAYFGEI 77

  Fly    97 GFGTPKSQPVTLLVDTASANLLVYSSEFVKQSCLHHDGYNSSESQTYQANGSPFQIQFASQEILT 161
            ..||| .|...:|.||.|:||.|.|.....|:|..|..:|.|||.||..||..|.:|:.|.. ||
Human    78 SIGTP-PQNFLVLFDTGSSNLWVPSVYCQSQACTSHSRFNPSESSTYSTNGQTFSLQYGSGS-LT 140

  Fly   162 GILSTDTFTLGDLVIKNQTFAEINSAPTDMCKRSNFDGIIGLGFSEIALNGVETPLDNILEQGLI 226
            |....||.|:..:.:.||.|....:.|......:.||||:||.:..::::...|.:..::::|.:
Human   141 GFFGYDTLTVQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLAYPALSVDEATTAMQGMVQEGAL 205

  Fly   227 DEPIFSLYVNRNASDASNGGVLLLGGSDPTLYSGCLTYVPVSKVGFWQITVGQVEIGSKK--LCS 289
            ..|:||:|::.  ...|:||.::.||.|.:||:|.:.:.||::..:|||.:.:..||.:.  .||
Human   206 TSPVFSVYLSN--QQGSSGGAVVFGGVDSSLYTGQIYWAPVTQELYWQIGIEEFLIGGQASGWCS 268

  Fly   290 -NCQAIFDMGTSLIIVPCPALKIINKKLGIKETDRKDGVYIIDCKKVSHLPKIVFNIGWKDFTLN 353
             .||||.|.||||:.||...:..:.:..|.:|.:.  |.::::|..:.:||.:.|.|...:|.|.
Human   269 EGCQAIVDTGTSLLTVPQQYMSALLQATGAQEDEY--GQFLVNCNSIQNLPSLTFIINGVEFPLP 331

  Fly   354 PSDYILNYSGTCVSGF--SSLSDCNGTQTNDDSEDLNNIWVFGDVFFGAIFTLFDFGLKLVGMA 415
            ||.|||:.:|.|..|.  :.||..||          ..:|:.||||..:.::::|.|...||.|
Human   332 PSSYILSNNGYCTVGVEPTYLSSQNG----------QPLWILGDVFLRSYYSVYDLGNNRVGFA 385

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG31928NP_722705.1 Asp 91..416 CDD:394983 110/330 (33%)
PGCNP_002621.1 A1_Propeptide 20..46 CDD:462326 9/25 (36%)
gastricsin 70..387 CDD:133144 110/339 (32%)

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