Protein Alignment CG31926 and NAPSA

DIOPT Version :9

• Sequence 1: NP_001259870.1
• Gene: CG31926 / 326174
• FlyBaseID: FBgn0051926
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_004842.1
• Gene: NAPSA / 9476
• HGNCID: 13395
• Length: 420
• Species: Homo sapiens
• Alignment Length: 395
• Identity: 136/395 - (34%)
• Similarity: 197/395 - (49%)
• Gaps: 31/395 - (7%)

  Fly    15 LTVLAVLAFEAEARKRVRIGLHKNPEPIEENIKNELKTLSIKHNLNVDDTKAKTKTDTKVPGSK- 78
            |.:|.:|..|......:||.||: .:| ...|.|.|:.......|        .|.....||.|
Human    11 LLLLPLLNVEPSGATLIRIPLHR-VQP-GRRILNLLRGWREPAEL--------PKLGAPSPGDKP 65

  Fly    79 -VATLENLYNTEYYTTLGFGNPPQDLKVLIDTGSANLWVLSSKCPDSVAPCANRIKYNSSASTTY 142
             ...|.|..:.:|:..:|.|.|||:..|..||||:||||.|.:|.....||....:::..||:::
Human    66 IFVPLSNYRDVQYFGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDPKASSSF 130

  Fly   143 RAINTAFNIAYGSNSEEGPIALSGFQSQDTVNFAGYSIKNQIFAEITNAPETAFLKSQLDGILGL 207
            :|..|.|.|.||:.      .:.|..|:|.:...|....:.||.|....|...|..:..||||||
Human   131 QANGTKFAIQYGTG------RVDGILSEDKLTIGGIKGASVIFGEALWEPSLVFAFAHFDGILGL 189

  Fly   208 GFASIAINSITPPFYNLMAQGLVNRSVFSIYLNRNGTNAINGGELILGGSDSGLYSGCLTYVPVS 272
            ||..:::..:.||...|:.|||:::.|||.||||:.... :||||:|||||...|...||:|||:
Human   190 GFPILSVEGVRPPMDVLVEQGLLDKPVFSFYLNRDPEEP-DGGELVLGGSDPAHYIPPLTFVPVT 253

  Fly   273 SAGYWQFTMTSANLN-GFQFC-ENCEAILDVGTSLIVVPEQVLDTINQILGVLNPTASNGVFLVD 335
            ...|||..|....:. |...| :.|.||||.|||||..|.:.:..::..:|.:...|  |.:::.
Human   254 VPAYWQIHMERVKVGPGLTLCAKGCAAILDTGTSLITGPTEEIRALHAAIGGIPLLA--GEYIIL 316

  Fly   336 CSSIGDLPDIVFTVARRKFPLKSSDYVL---RYG-NTCVSGFTSMN----GNSLLILGEIFLGAY 392
            ||.|..||.:.|.:....|.|.:.|||:   |.| ..|:|||.:::    .....|||::|||.|
Human   317 CSEIPKLPAVSFLLGGVWFNLTAHDYVIQTTRNGVRLCLSGFQALDVPPPAGPFWILGDVFLGTY 381

  Fly   393 YTTYD 397
            ...:|
Human   382 VAVFD 386

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31926	NP_001259870.1	pepsin_retropepsin_like	82..406	CDD:299705	119/326 (37%)
		Asp	89..408	CDD:278455	117/319 (37%)
NAPSA	NP_004842.1	pepsin_retropepsin_like	72..399	CDD:299705	118/324 (36%)
		Asp	77..401	CDD:278455	117/319 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54317
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	6	5.880