DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31926 and YPS7

DIOPT Version :9

Sequence 1:	NP_001259870.1	Gene:	CG31926 / 326174	FlyBaseID:	FBgn0051926	Length:	410	Species:	Drosophila melanogaster
Sequence 2:	NP_010636.1	Gene:	YPS7 / 851950	SGDID:	S000002757	Length:	596	Species:	Saccharomyces cerevisiae

Alignment Length:	450	Identity:	101/450 - (22%)
Similarity:	156/450 - (34%)	Gaps:	145/450 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    65 KAKTKTDTKVPGSKVATLENLYNTEYYTTLGFGNPPQDLKVLIDTGSANLWVLSSKCPDSVAPCA 129
            |:.|.:.|:.|...:|..:: ....||....||.|.|..::|:|.               :.|..
Yeast    32 KSGTSSSTEEPFPVLAVGKD-GRGNYYVNSTFGTPGQRQRLLVDI---------------IQPYI 80

  Fly   130 NRIKYNSSASTTYRAINTAFNIAYGSNSEEGPIALSGFQ----------------SQDTVNFAGY 178
            |.:...|.:...|..:... :.:|..|.....:.:|..|                ..|.:||...
Yeast    81 NLVSGTSESHNEYSGVYHK-HPSYLMNDSTSSVPVSPGQIYEISFIDGRAVNCTLVTDDMNFTNV 144

  Fly   179 SIKNQIFAEITNAPET----------------AFLKSQ-----LDGILGLGFASIAINSITPP-- 220
            |.:|...|.||:...|                :|...|     ..|:|||.      ..:|.|
Yeast   145 SSENSSTALITDLMVTRDNVQFNSGSLSISNVSFFDIQSSNFKTSGLLGLS------GKVTNPGN 203

  Fly   221 ------------FYNLMAQG-LVNRSVFSIYLNRNGTN-------AINGGELILGGSDSGLYSGC 265
                        |.:|:... ::..|.:|::|..:.:.       ..|.|:|:|||.|..|::|.
Yeast   204 AIDSSQYTEQSYFLSLLKDADIIESSSYSLWLAGDTSTYKTYRDPISNCGKLLLGGVDPSLFTGT 268

  Fly   266 L------TYV-PVSSA---GYWQFTM----------TSANLNGFQFCENCEAILDVGTSLIVVPE 310
            |      .|| |||:|   ||....:          .|.|:....|..  .|:||..:|:..:|
Yeast   269 LGKFDLIPYVDPVSNAVSVGYPIVPLGPIYIVSNSGQSLNMTSKDFLS--PALLDSTSSVSYLP- 330

  Fly   311 QVLDTINQILGVLNPTASNGV--FLVDCS------SIG-DLPDIVFTVARRKFPLKSSDY----- 361
              ..||.||...:..|....:  :||.||      |:| .|.::...:..|  .|.||.|
Yeast   331 --TSTIIQIAVQIAATYVESLDRWLVQCSIADMGVSLGFRLRELTIEIPLR--DLLSSTYDTSTN 391

  Fly   362 -------------VLRYGNTCVSGFTSMNGNSLLILGEIFLGAYYTTYDIVYKLIGLAPA 408
                         :..|.||    .|.:|     ||||.|:...|...|:....|.:|.|
Yeast   392 SSMFFSSGQEACFLTLYANT----NTGVN-----ILGEAFIKNIYMAMDLEDNTIAIAQA 442

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31926	NP_001259870.1	pepsin_retropepsin_like	82..406	CDD:299705	94/429 (22%)
CG31926	NP_001259870.1	Asp	89..408	CDD:278455	95/424 (22%)
YPS7	NP_010636.1	pepsin_retropepsin_like	162..442	CDD:416259	70/301 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157341742
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.830