DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31926 and NANA

DIOPT Version :9

Sequence 1:	NP_001259870.1	Gene:	CG31926 / 326174	FlyBaseID:	FBgn0051926	Length:	410	Species:	Drosophila melanogaster
Sequence 2:	NP_187876.2	Gene:	NANA / 820452	AraportID:	AT3G12700	Length:	461	Species:	Arabidopsis thaliana

Alignment Length:	497	Identity:	113/497 - (22%)
Similarity:	169/497 - (34%)	Gaps:	160/497 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 KLLLFWLTVLAVLAFEAEARK--RVRIGL-HKN---PEP---IEENIKNELK---TLSIKHNLNV 61
            |.||..|....:|...|::.|  .||:.| |::   |:|   ||:.|..:.|   .:|.|.|..|
plant    25 KTLLSCLITTLLLITVADSMKDTSVRLKLAHRDTLLPKPLSRIEDVIGADQKRHSLISRKRNSTV 89

  Fly    62 DDTKAKTKTDTKVPGSKVATLENLYNT-EYYTTLGFGNPPQDLKVLIDTGSANLWVL-------- 117
            .     .|.|.   ||.:.     |.| :|:|.:..|.|.:..:|::||||...||.
plant    90 G-----VKMDL---GSGID-----YGTAQYFTEIRVGTPAKKFRVVVDTGSELTWVNCRYRARGK 141

  Fly   118 ---------SSK------------------------CPDSVAPCANRIKY--NSSASTTYRAINT 147
                     .||                        ||....||:...:|  .|:|...:.....
plant   142 DNRRVFRADESKSFKTVGCLTQTCKVDLMNLFSLTTCPTPSTPCSYDYRYADGSAAQGVFAKETI 206

  Fly   148 AFNIAYGSNSEEGPIALSGFQSQDTVNFAGYSIKNQIFAEITNAPETAFLKSQLDGILGLGFASI 212
            ...:..|..:.. |..|.|..|    :|.|.|.:.                  .||:|||.|:..
plant   207 TVGLTNGRMARL-PGHLIGCSS----SFTGQSFQG------------------ADGVLGLAFSDF 248

  Fly   213 AINSITPPFYNLMAQGLVNRSVFSIYL-----NRNGTNAINGGELILGGSDSGLYSG------CL 266
            :..|.....|.         :.||..|     |:|.:|     .||.|.|.|...:.      .|
plant   249 SFTSTATSLYG---------AKFSYCLVDHLSNKNVSN-----YLIFGSSRSTKTAFRRTTPLDL 299

  Fly   267 TYVPV--------SSAGY---------WQFTMTSANLNGFQFCENCEAILDVGTSLIVVPE---- 310
            |.:|.        .|.||         |..|....            .|||.||||.::.:
plant   300 TRIPPFYAINVIGISLGYDMLDIPSQVWDATSGGG------------TILDSGTSLTLLADAAYK 352

  Fly   311 QVLDTINQILGVLNPTASNGVFLVDCSS------IGDLPDIVFTV-ARRKFPLKSSDYVL--RYG 366
            ||:..:.:.|..|......||.:..|.|      :..||.:.|.: ...:|......|::  ..|
plant   353 QVVTGLARYLVELKRVKPEGVPIEYCFSFTSGFNVSKLPQLTFHLKGGARFEPHRKSYLVDAAPG 417

  Fly   367 NTCVSGFTSMNGNSLLILGEIFLGAYYTTYDIVYKLIGLAPA 408
            ..|: ||.|....:..::|.|....|...:|::...:..||:
plant   418 VKCL-GFVSAGTPATNVIGNIMQQNYLWEFDLMASTLSFAPS 458

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31926	NP_001259870.1	pepsin_retropepsin_like	82..406	CDD:299705	86/408 (21%)
CG31926	NP_001259870.1	Asp	89..408	CDD:278455	85/402 (21%)
NANA	NP_187876.2	pepsin_A_like_plant	105..460	CDD:133143	86/404 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D753343at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820