Protein Alignment CG31926 and Bace

DIOPT Version :9

• Sequence 1: NP_001259870.1
• Gene: CG31926 / 326174
• FlyBaseID: FBgn0051926
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_001285756.1
• Gene: Bace / 34182
• FlyBaseID: FBgn0032049
• Length: 372
• Species: Drosophila melanogaster
• Alignment Length: 396
• Identity: 168/396 - (42%)
• Similarity: 235/396 - (59%)
• Gaps: 33/396 - (8%)

  Fly    15 LTVLAVLAFEAEARKRVRIGLHKNPEPIEENIKNELKTLSIKHNLNVDDTKAKTKTDTKVPGSKV 79
            :.|:.:||..|.|.      ||:.|...|:|.        :|...||...|:..:|..::|..:.
  Fly     5 IAVVVLLAALASAE------LHRVPILKEQNF--------VKTRQNVLAEKSYLRTKYQLPSLRS 55

  Fly    80 A---TLENLYNTEYYTTLGFGNPPQDLKVLIDTGSANLWVLSSKCPDSVAPCANRIKYNSSASTT 141
            .   .|.|..|..||..:..|.|.|..|||.|:||:||||.|:.|....  |....:|:||||:|
  Fly    56 VDEEQLSNSMNMAYYGAISIGTPAQSFKVLFDSGSSNLWVPSNTCKSDA--CLTHNQYDSSASST 118

  Fly   142 YRAINTAFNIAYGSNSEEGPIALSGFQSQDTVNFAGYSIKNQIFAEITNAPETAFLKSQLDGILG 206
            |.|...:|:|.||:.|      |:|:.|.|||:..|.||::|.|||.||.|.|.|..:..|||||
  Fly   119 YVANGESFSIQYGTGS------LTGYLSTDTVDVNGLSIQSQTFAESTNEPGTNFNDANFDGILG 177

  Fly   207 LGFASIAINSITPPFYNLMAQGLVNRSVFSIYLNRNGTNAINGGELILGGSDSGLYSGCLTYVPV 271
            :.:.|:|::.:.|||||:::||||:.||||.||.|:||:.: |||||.||||:.||||.|||||:
  Fly   178 MAYESLAVDGVAPPFYNMVSQGLVDNSVFSFYLARDGTSTM-GGELIFGGSDASLYSGALTYVPI 241

  Fly   272 SSAGYWQFTMTSANLNGFQFCENCEAILDVGTSLIVVPEQVLDTINQILGVLNPTASNGVFLVDC 336
            |..|||||||..::::|:..|::|:||.|.||||||.|.....|:::||.|    ..:|  .:||
  Fly   242 SEQGYWQFTMAGSSIDGYSLCDDCQAIADTGTSLIVAPYNAYITLSEILNV----GEDG--YLDC 300

  Fly   337 SSIGDLPDIVFTVARRKFPLKSSDYVLRYGNTCVSGFTSMNGNSLLILGEIFLGAYYTTYDIVYK 401
            ||:..|||:.|.:....|.||.|.|:::....|:|.|..| |....|||::|:|.|||.:|:...
  Fly   301 SSVSSLPDVTFNIGGTNFVLKPSAYIIQSDGNCMSAFEYM-GTDFWILGDVFIGQYYTEFDLGNN 364

  Fly   402 LIGLAP 407
            .||.||
  Fly   365 RIGFAP 370

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31926	NP_001259870.1	pepsin_retropepsin_like	82..406	CDD:299705	150/323 (46%)
		Asp	89..408	CDD:278455	149/319 (47%)
Bace	NP_001285756.1	pepsin_retropepsin_like	59..369	CDD:299705	150/325 (46%)
		Asp	68..371	CDD:278455	149/319 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45455531
Domainoid	1	1.000	97	1.000	Domainoid score	I1884
eggNOG	1	0.900	-	-		E1_KOG1339
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	97	1.000	Inparanoid score	I1684
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D356089at33208
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR47966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.900