Sequence 1: | NP_001259870.1 | Gene: | CG31926 / 326174 | FlyBaseID: | FBgn0051926 | Length: | 410 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_036236.1 | Gene: | BACE1 / 23621 | HGNCID: | 933 | Length: | 501 | Species: | Homo sapiens |
Alignment Length: | 387 | Identity: | 97/387 - (25%) |
---|---|---|---|
Similarity: | 171/387 - (44%) | Gaps: | 63/387 - (16%) |
- Green bases have known domain annotations that are detailed below.
Fly 67 KTKTDTKVPGSKVATLENLYNTE------YYTTLGFGNPPQDLKVLIDTGSANLWVLSSKCPDSV 125
Fly 126 APCANRIKYNSSASTTYRAINTAFNIAYGSNSEEGPIALSGFQSQDTVNF---AGYSIKNQIFAE 187
Fly 188 ITNAPETAFLKSQLDGILGLGFASIA--INSITPPFYNLMAQGLVNRSVFSIY-------LNRNG 243
Fly 244 TNAINGGELILGGSDSGLYSGCLTYVPVSSAGYWQFTMTSANLNGFQFCENC------EAILDVG 302
Fly 303 TSLIVVPEQVLDTINQILGVLNPTAS--NGVFLVD---CSSIGDLPDIVF--------------- 347
Fly 348 ---TVARRKFPLKSSDYVLRYGNTCVSGFTSMNGNSLLILGEIFLGAYYTTYDIVYKLIGLA 406 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
CG31926 | NP_001259870.1 | pepsin_retropepsin_like | 82..406 | CDD:299705 | 93/370 (25%) |
Asp | 89..408 | CDD:278455 | 92/365 (25%) | ||
BACE1 | NP_036236.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 39..58 | 3/11 (27%) | |
beta_secretase_like | 72..437 | CDD:133140 | 92/361 (25%) | ||
Interaction with RTN3 | 479..501 | ||||
DXXLL. /evidence=ECO:0000269|PubMed:15886016 | 496..500 | ||||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_KOG1339 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 1 | 0.950 | - | 0 | Normalized mean entropy | S4239 |
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 1 | 1.010 | - | - | D753343at2759 | |
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
4 | 3.770 |