Protein Alignment CG31926 and Ren2

DIOPT Version :10

• Sequence 1: NP_722706.1
• Gene: CG31926 / 326174
• FlyBaseID: FBgn0051926
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_112470.2
• Gene: Ren2 / 19702
• MGIID: 97899
• Length: 424
• Species: Mus musculus
• Alignment Length: 424
• Identity: 151/424 - (35%)
• Similarity: 212/424 - (50%)
• Gaps: 43/424 - (10%)

  Fly     2 RVRWNHFKLLLFW----LTVLAVLAFEAEARKRVRIGLHKNP---EPIEENIKNELKTLSIKHNL 59
            |.|...:.|||.|    .::.....||       ||.|.|.|   |.:||. ..::..||.:.::
Mouse    26 RRRMPLWALLLLWSPCTFSLPTGTTFE-------RIPLKKMPSVREILEER-GVDMTRLSAEWDV 82

  Fly    60 NVDDTKAKTKTDTKVPGSKVATLENLYNTEYYTTLGFGNPPQDLKVLIDTGSANLWVLSSKCPDS 124
               .||..:.||...|    ..|.|..|::||..:|.|.|||..||:.|||||||||.|:||...
Mouse    83 ---FTKRSSLTDLISP----VVLTNYLNSQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRL 140

  Fly   125 VAPCANRIKYNSSASTTYRAINTAFNIAYGSNSEEGPIALSGFQSQDTVNFAGYSIKNQIFAEIT 189
            ...|.....|.||.|::|......|.|.|||.      .:.||.|||:|...|.:: .|.|.|:|
Mouse   141 YLACGIHSLYESSDSSSYMENGDDFTIHYGSG------RVKGFLSQDSVTVGGITV-TQTFGEVT 198

  Fly   190 NAPETAFLKSQLDGILGLGFASIAINSITPPFYNLMAQGLVNRSVFSIYLNRNGTNAINGGELIL 254
            ..|...|:.:|.||:||:||.:.|:..:||.|.::::||::...|||:|.|| |.:.: |||::|
Mouse   199 ELPLIPFMLAQFDGVLGMGFPAQAVGGVTPVFDHILSQGVLKEKVFSVYYNR-GPHLL-GGEVVL 261

  Fly   255 GGSDSGLYSGCLTYVPVSSAGYWQFTMTSANL-NGFQFC-ENCEAILDVGTSLIVVPEQVLDTIN 317
            ||||...|.|...||.:|....||.||...:: :....| |.||.::|.|:|.|..|...|..|.
Mouse   262 GGSDPEHYQGDFHYVSLSKTDSWQITMKGVSVGSSTLLCEEGCEVVVDTGSSFISAPTSSLKLIM 326

  Fly   318 QILGVLNPTASNGVFLVDCSSIGDLPDIVFTVARRKFPLKSSDYVLRYGN----TCVSGFTSMN- 377
            |.||........  ::|.||.:..||||.|.:..|.:.|.|:||||:|.|    .|.....:|:
Mouse   327 QALGAKEKRLHE--YVVSCSQVPTLPDISFNLGGRAYTLSSTDYVLQYPNRRDKLCTVALHAMDI 389

  Fly   378 ---GNSLLILGEIFLGAYYTTYDIVYKLIGLAPA 408
               ...:.:||..|:..:||.:|.....||.|.|
Mouse   390 PPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALA 423

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31926	NP_722706.1	Asp	89..408	CDD:394983	124/328 (38%)
Ren2	NP_112470.2	A1_Propeptide	53..>71	CDD:462326	8/18 (44%)
		renin_like	98..423	CDD:133154	127/335 (38%)