DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG31926 and Ctsd

DIOPT Version :10

Sequence 1:NP_722706.1 Gene:CG31926 / 326174 FlyBaseID:FBgn0051926 Length:410 Species:Drosophila melanogaster
Sequence 2:NP_599161.2 Gene:Ctsd / 171293 RGDID:621511 Length:407 Species:Rattus norvegicus


Alignment Length:424 Identity:153/424 - (36%)
Similarity:222/424 - (52%) Gaps:57/424 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly    15 LTVLAVLAFEAEARKRVRIGLHKNPEPIEENIKNELKTLSIKHNL-----NVDD-------TKAK 67
            |.:|.:||..:.|..|:         |:.       |..||:..:     :|:|       ||..
  Rat     8 LLILGLLAASSSALIRI---------PLR-------KFTSIRRTMTEVGGSVEDLILKGPITKYS 56

  Fly    68 TKTD--TKVPGSKVATLENLYNTEYYTTLGFGNPPQDLKVLIDTGSANLWVLSSKCPDSVAPCAN 130
            .::.  ||.|.|::  |:|..:.:||..:|.|.|||...|:.||||:||||.|..|......|..
  Rat    57 MQSSPRTKEPVSEL--LKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWV 119

  Fly   131 RIKYNSSASTTYRAINTAFNIAYGSNSEEGPIALSGFQSQDTV------NFAGYSIKNQIFAEIT 189
            ..||||..|:||....|:|:|.|||.|      |||:.|||||      :..|..::.|||.|.|
  Rat   120 HHKYNSDKSSTYVKNGTSFDIHYGSGS------LSGYLSQDTVSVPCKSDLGGIKVEKQIFGEAT 178

  Fly   190 NAPETAFLKSQLDGILGLGFASIAINSITPPFYNLMAQGLVNRSVFSIYLNRNGTNAINGGELIL 254
            ..|...|:.::.|||||:|:..|::|::.|.|.|||.|.||.:::||.||||:.|.. .||||:|
  Rat   179 KQPGVVFIAAKFDGILGMGYPFISVNNVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQ-PGGELML 242

  Fly   255 GGSDSGLYSGCLTYVPVSSAGYWQFTMTSANLNG-FQFCE-NCEAILDVGTSLIVVPEQVLDTIN 317
            ||:||..|.|.|:|:.|:...|||..|....:.. ...|: .||||:|.||||:|.|...:..:.
  Rat   243 GGTDSRYYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVKELQ 307

  Fly   318 QILGVLNPTASNGVFLVDCSSIGDLPDIVFTVARRKFPLKSSDYVLRY---GNT-CVSGFTSMN- 377
            :.:|.:  ....|.:::.|..:..||.|.|.:..:.:.|....|:|:.   |.| |:|||..|: 
  Rat   308 KAIGAV--PLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLSGFMGMDI 370

  Fly   378 ---GNSLLILGEIFLGAYYTTYDIVYKLIGLAPA 408
               ...|.|||::|:|.|||.:|..|..:|.|.|
  Rat   371 PPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKA 404

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG31926NP_722706.1 Asp 89..408 CDD:394983 132/334 (40%)
CtsdNP_599161.2 A1_Propeptide 23..49 CDD:462326 7/41 (17%)
Cathepsin_D2 73..403 CDD:133157 132/338 (39%)

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