Protein Alignment CG31926 and Ctsd

DIOPT Version :9

• Sequence 1: NP_001259870.1
• Gene: CG31926 / 326174
• FlyBaseID: FBgn0051926
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_599161.2
• Gene: Ctsd / 171293
• RGDID: 621511
• Length: 407
• Species: Rattus norvegicus
• Alignment Length: 424
• Identity: 153/424 - (36%)
• Similarity: 222/424 - (52%)
• Gaps: 57/424 - (13%)

  Fly    15 LTVLAVLAFEAEARKRVRIGLHKNPEPIEENIKNELKTLSIKHNL-----NVDD-------TKAK 67
            |.:|.:||..:.|..|:         |:.       |..||:..:     :|:|       ||..
  Rat     8 LLILGLLAASSSALIRI---------PLR-------KFTSIRRTMTEVGGSVEDLILKGPITKYS 56

  Fly    68 TKTD--TKVPGSKVATLENLYNTEYYTTLGFGNPPQDLKVLIDTGSANLWVLSSKCPDSVAPCAN 130
            .::.  ||.|.|::  |:|..:.:||..:|.|.|||...|:.||||:||||.|..|......|..
  Rat    57 MQSSPRTKEPVSEL--LKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWV 119

  Fly   131 RIKYNSSASTTYRAINTAFNIAYGSNSEEGPIALSGFQSQDTV------NFAGYSIKNQIFAEIT 189
            ..||||..|:||....|:|:|.|||.|      |||:.|||||      :..|..::.|||.|.|
  Rat   120 HHKYNSDKSSTYVKNGTSFDIHYGSGS------LSGYLSQDTVSVPCKSDLGGIKVEKQIFGEAT 178

  Fly   190 NAPETAFLKSQLDGILGLGFASIAINSITPPFYNLMAQGLVNRSVFSIYLNRNGTNAINGGELIL 254
            ..|...|:.::.|||||:|:..|::|::.|.|.|||.|.||.:::||.||||:.|.. .||||:|
  Rat   179 KQPGVVFIAAKFDGILGMGYPFISVNNVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQ-PGGELML 242

  Fly   255 GGSDSGLYSGCLTYVPVSSAGYWQFTMTSANLNG-FQFCE-NCEAILDVGTSLIVVPEQVLDTIN 317
            ||:||..|.|.|:|:.|:...|||..|....:.. ...|: .||||:|.||||:|.|...:..:.
  Rat   243 GGTDSRYYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVKELQ 307

  Fly   318 QILGVLNPTASNGVFLVDCSSIGDLPDIVFTVARRKFPLKSSDYVLRY---GNT-CVSGFTSMN- 377
            :.:|.:  ....|.:::.|..:..||.|.|.:..:.:.|....|:|:.   |.| |:|||..|:
  Rat   308 KAIGAV--PLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLSGFMGMDI 370

  Fly   378 ---GNSLLILGEIFLGAYYTTYDIVYKLIGLAPA 408
               ...|.|||::|:|.|||.:|..|..:|.|.|
  Rat   371 PPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKA 404

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31926	NP_001259870.1	pepsin_retropepsin_like	82..406	CDD:299705	133/339 (39%)
		Asp	89..408	CDD:278455	132/334 (40%)
Ctsd	NP_599161.2	A1_Propeptide	21..46	CDD:285240	6/40 (15%)
		Cathepsin_D2	73..403	CDD:133157	132/338 (39%)
		Asp	78..404	CDD:278455	132/334 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54317
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47966
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.920