Protein Alignment CG31926 and CTSE

DIOPT Version :9

• Sequence 1: NP_001259870.1
• Gene: CG31926 / 326174
• FlyBaseID: FBgn0051926
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: XP_011507546.1
• Gene: CTSE / 1510
• HGNCID: 2530
• Length: 401
• Species: Homo sapiens
• Alignment Length: 427
• Identity: 143/427 - (33%)
• Similarity: 213/427 - (49%)
• Gaps: 54/427 - (12%)

  Fly     9 KLLLFWLTVLAVLAFEAEARKRVRIGLHKNPEPIEENIKNELKTLS------IKHNLNVDDTKAK 67
            |.||..|.||..|. ||:.      .||:.|.....::|.:|:..|      ..|||::......
Human     2 KTLLLLLLVLLELG-EAQG------SLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTES 59

  Fly    68 TKTD--TKVPGSKVATLENLYNTEYYTTLGFGNPPQDLKVLIDTGSANLWVLSSKCPDSVAPCAN 130
            ...|  .|.|      |.|..:.||:.|:..|:|||:..|:.||||:||||.|..|....  |..
Human    60 CSMDQSAKEP------LINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPA--CKT 116

  Fly   131 RIKYNSSASTTYRAINTAFNIAYGSNSEEGPIALSGFQSQDTVNFAGYSIK-----NQIFAEITN 190
            ..::..|.|:||.....:|:|.||:.|      |||....|.|:...|.::     .|.|.|...
Human   117 HSRFQPSQSSTYSQPGQSFSIQYGTGS------LSGIIGADQVSAFSYQVEGLTVVGQQFGESVT 175

  Fly   191 APETAFLKSQLDGILGLGFASIAINSITPPFYNLMAQGLVNRSVFSIYLNRNGTNAINGGELILG 255
            .|...|:.::.|||||||:.|:|:..:||.|.|:|||.||:..:||:|::.|..... |.|||.|
Human   176 EPGQTFVDAEFDGILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGA-GSELIFG 239

  Fly   256 GSDSGLYSGCLTYVPVSSAGYWQFTMTSANLNG-FQFC-ENCEAILDVGTSLIVVPEQVLDTINQ 318
            |.|...:||.|.:|||:...|||..:.:..:.| ..|| |.|:||:|.|||||..|.   |.|.|
Human   240 GYDHSHFSGSLNWVPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPS---DKIKQ 301

  Fly   319 ILGVLNPTASNGVFLVDCSSIGDLPDIVFTVARRKFPLKSSDYVL-------RYGNTCVSGFTSM 376
            :...:.....:|.:.|:|:::..:||:.||:....:.|..:.|.|       ::   |.|||..:
Human   302 LQNAIGAAPVDGEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQF---CSSGFQGL 363

  Fly   377 N----GNSLLILGEIFLGAYYTTYDIVYKLIGLAPAI 409
            :    ...|.|||::|:..:|:.:|.....:|||||:
Human   364 DIHPPAGPLWILGDVFIRQFYSVFDRGNNRVGLAPAV 400

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31926	NP_001259870.1	pepsin_retropepsin_like	82..406	CDD:299705	118/341 (35%)
		Asp	89..408	CDD:278455	118/336 (35%)
CTSE	XP_011507546.1	A1_Propeptide	21..49	CDD:285240	6/27 (22%)
		Asp	77..399	CDD:278455	118/336 (35%)
		Cathespin_E	78..398	CDD:133153	116/334 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165151481
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54317
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.850