Protein Alignment CG31926 and Ctsd

DIOPT Version :9

• Sequence 1: NP_001259870.1
• Gene: CG31926 / 326174
• FlyBaseID: FBgn0051926
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_034113.1
• Gene: Ctsd / 13033
• MGIID: 88562
• Length: 410
• Species: Mus musculus
• Alignment Length: 431
• Identity: 149/431 - (34%)
• Similarity: 220/431 - (51%)
• Gaps: 59/431 - (13%)

  Fly    10 LLLFWLTVLAVLAFEAEARKRVRIGLHKNPEPIEENIKNELKTLSIKHNL-----NVDD------ 63
            :||..|.:||..:|..     :||.|.              |..||:..:     :|:|
Mouse     6 VLLLILGLLASSSFAI-----IRIPLR--------------KFTSIRRTMTEVGGSVEDLILKGP 51

  Fly    64 -TKAKTKTDTKVPGSKVATLENLYNTEYYTTLGFGNPPQDLKVLIDTGSANLWVLSSKCPDSVAP 127
             ||...::..|........|:|..:.:||..:|.|.|||...|:.||||:||||.|..|......
Mouse    52 ITKYSMQSSPKTTEPVSELLKNYLDAQYYGDIGIGTPPQCFTVVFDTGSSNLWVPSIHCKILDIA 116

  Fly   128 CANRIKYNSSASTTYRAINTAFNIAYGSNSEEGPIALSGFQSQDTVNF---------AGYSIKNQ 183
            |....||||..|:||....|:|:|.|||.|      |||:.|||||:.         .|..::.|
Mouse   117 CWVHHKYNSDKSSTYVKNGTSFDIHYGSGS------LSGYLSQDTVSVPCKSDQSKARGIKVEKQ 175

  Fly   184 IFAEITNAPETAFLKSQLDGILGLGFASIAINSITPPFYNLMAQGLVNRSVFSIYLNRNGTNAIN 248
            ||.|.|..|...|:.::.|||||:|:..|::|::.|.|.|||.|.||::::||.||||: .....
Mouse   176 IFGEATKQPGIVFVAAKFDGILGMGYPHISVNNVLPVFDNLMQQKLVDKNIFSFYLNRD-PEGQP 239

  Fly   249 GGELILGGSDSGLYSGCLTYVPVSSAGYWQFTMTSANL-NGFQFCE-NCEAILDVGTSLIVVPEQ 311
            ||||:|||:||..|.|.|:|:.|:...|||..|....: |....|: .||||:|.||||:|.|.:
Mouse   240 GGELMLGGTDSKYYHGELSYLNVTRKAYWQVHMDQLEVGNELTLCKGGCEAIVDTGTSLLVGPVE 304

  Fly   312 VLDTINQILGVLNPTASNGVFLVDCSSIGDLPDIVFTVARRKFPLKSSDYVLRY---GNT-CVSG 372
            .:..:.:.:|.:  ....|.:::.|..:..||.:...:..:.:.|....|:|:.   |.| |:||
Mouse   305 EVKELQKAIGAV--PLIQGEYMIPCEKVSSLPTVYLKLGGKNYELHPDKYILKVSQGGKTICLSG 367

  Fly   373 FTSMN----GNSLLILGEIFLGAYYTTYDIVYKLIGLAPAI 409
            |..|:    ...|.|||::|:|:|||.:|.....:|.|.|:
Mouse   368 FMGMDIPPPSGPLWILGDVFIGSYYTVFDRDNNRVGFANAV 408

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31926	NP_001259870.1	pepsin_retropepsin_like	82..406	CDD:299705	130/342 (38%)
		Asp	89..408	CDD:278455	129/337 (38%)
Ctsd	NP_034113.1	A1_Propeptide	21..46	CDD:285240	7/43 (16%)
		Cathepsin_D2	73..405	CDD:133157	129/340 (38%)
		Asp	78..407	CDD:278455	129/337 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54317
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.880