DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31926 and LOC101733630

DIOPT Version :9

Sequence 1:	NP_001259870.1	Gene:	CG31926 / 326174	FlyBaseID:	FBgn0051926	Length:	410	Species:	Drosophila melanogaster
Sequence 2:	XP_012817292.3	Gene:	LOC101733630 / 101733630	-ID:	-	Length:	343	Species:	Xenopus tropicalis

Alignment Length:	342	Identity:	127/342 - (37%)
Similarity:	189/342 - (55%)	Gaps:	23/342 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 SKVATLENLYNTEYYTTLGFGNPPQDLKVLIDTGSANLWVLSSKCPDSVAPCANRIKYNSSASTT 141
            |:|..|:    .:||..:|.|:|||:..|:.||||:||||.|..|......|....||:||.|:|
Frog    14 SRVLYLQ----AQYYGEIGLGSPPQNFTVVFDTGSSNLWVPSVHCSMLDIACWMHHKYDSSKSST 74

  Fly   142 YRAINTAFNIAYGSNSEEGPIALSGFQSQDTVNFAGYSIKNQIFAEITNAPETAFLKSQLDGILG 206
            |....|||.|.||:.|      |||:.|:|||.....::|.|:|.|....|...|:.::.|||||
Frog    75 YVKNGTAFAIQYGTGS------LSGYLSKDTVTIGNLAVKGQMFGEAVKQPGVTFVAAKFDGILG 133

  Fly   207 LGFASIAINSITPPFYNLMAQGLVNRSVFSIYLNRNGTNAINGGELILGGSDSGLYSGCLTYVPV 271
            :.:..|:::.:.|.|.|:|||.||..::||.||||| .:...||||:|||:|...|:|...|:.|
Frog   134 MAYPVISVDGVPPVFDNIMAQKLVESNIFSFYLNRN-PDTQPGGELLLGGTDPKYYTGDFHYLNV 197

  Fly   272 SSAGYWQFTMTSANL-NGFQFCE-NCEAILDVGTSLIVVPEQVLDTINQILGVLNPTASNGVFLV 334
            :...|||..|....: :....|: .||.|:|.|||||..|.:.:..:.:.:|.:  ....|.::|
Frog   198 TRKAYWQIHMDQLGVGDQLTLCKGGCEVIVDTGTSLITGPLEEVTALQKAIGAV--PLIQGQYMV 260

  Fly   335 DCSSIGDLPDIVFTVARRKFPLKSSDYVLRY---GNT-CVSGFTSMN----GNSLLILGEIFLGA 391
            .|..:..||.|..|:..:.:.|....|:::.   |:| |:|||..:|    ...|.|||::|:|.
Frog   261 QCDKVPTLPVISLTLGGQVYTLTGEQYIMKVSQRGSTICLSGFMGLNIPPPAGPLWILGDVFIGQ 325

  Fly   392 YYTTYDIVYKLIGLAPA 408
            ||:.:|..|..:|.|.|
Frog   326 YYSVFDRAYDRVGFAKA 342

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31926	NP_001259870.1	pepsin_retropepsin_like	82..406	CDD:299705	123/333 (37%)
CG31926	NP_001259870.1	Asp	89..408	CDD:278455	123/328 (38%)
LOC101733630	XP_012817292.3	Cathepsin_D2	18..341	CDD:133157	123/335 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54317
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	5.020