Protein Alignment CG31926 and bace2

DIOPT Version :10

• Sequence 1: NP_722706.1
• Gene: CG31926 / 326174
• FlyBaseID: FBgn0051926
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_001135590.1
• Gene: bace2 / 100216145
• XenbaseID: XB-GENE-1014090
• Length: 499
• Species: Xenopus tropicalis
• Alignment Length: 378
• Identity: 102/378 - (26%)
• Similarity: 161/378 - (42%)
• Gaps: 65/378 - (17%)

  Fly    75 PGSKVATLENLYNTE------YYTTLGFGNPPQDLKVLIDTGSANLWVLSSKCPDSVAPCANRIK 133
            ||.::.....:.|.|      ||..|..|.|||.:.:|:||||:|..|..:..||...      .
 Frog    54 PGGQINFFSMVNNLEGDSGRGYYLELLIGTPPQKMNILVDTGSSNFAVAGALNPDITT------F 112

  Fly   134 YNSSASTTYRAINTAFNIAYGSNSEEGPIALSGFQSQDTVNFAGYSIKNQIFAEITNAPETAFLK 198
            ::|..||:|..:||...:.|...|..|.:..........||  |..:.|  .|.|..: |..||.
 Frog   113 FDSKLSTSYEPLNTQVTVRYTQGSWTGLLGKDVISMPKGVN--GTFLIN--IASIFQS-ENFFLP 172

  Fly   199 S-QLDGILGLGFASIA-INSITPPFYNLMAQGLVNRSVFSIYLNRNGTNA----INGGELILGGS 257
            : ...|||||.::::| .:|...||::.:.|.....::||:.:...|..:    ||.|.|:|||.
 Frog   173 NINWQGILGLAYSTLAKPSSSVEPFFDSLVQQENIPNIFSMQMCGAGQPSPGIGINAGSLVLGGI 237

  Fly   258 DSGLYSGCLTYVPVSSAGYWQFTMTSANLNGFQFCENC------EAILDVGTSLIVVPEQV---- 312
            :..||.|.:.|.|::...|:|..:....:.|.....:|      :||:|.||:|:.:|::|
 Frog   238 EPSLYQGDIWYTPITEEWYYQVEVLKFEVGGQNLNLDCTVYNSDKAIVDSGTTLLRLPDKVFNAM 302

  Fly   313 LDTINQILGVLNPTAS--NGVFLVDCSSIGD----LPDIVF----TVARRKF--PLKSSDYV--- 362
            :|.|.|...:.|..|.  .|:.|.......|    .|||..    |.:.|.|  .||...|:
 Frog   303 VDAIVQTSLIQNFNAEFWAGLQLACWDKTQDPWNYFPDISIYLRDTNSSRSFRLTLKPQLYIQSV 367

  Fly   363 ---------LRYGNTCVSGFTSMNGNSLLILGEIFLGAYYTTYDIVYKLIGLA 406
                     .|:|.:        ...|.|::|...:..:|..:|...|.:|.|
 Frog   368 LTFQESLNCFRFGIS--------QSASALVIGATVMEGFYVIFDRAEKRVGFA 412

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31926	NP_722706.1	Asp	89..408	CDD:394983	99/364 (27%)
bace2	NP_001135590.1	beta_secretase_like	72..433	CDD:133140	98/360 (27%)