Protein Alignment Nepl3 and ece1

DIOPT Version :10

• Sequence 1: NP_608904.1
• Gene: Nepl3 / 326172
• FlyBaseID: FBgn0031678
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_001071260.3
• Gene: ece1 / 777750
• ZFINID: ZDB-GENE-061110-100
• Length: 766
• Species: Danio rerio
• Alignment Length: 710
• Identity: 130/710 - (18%)
• Similarity: 232/710 - (32%)
• Gaps: 245/710 - (34%)

  Fly    21 VCSANPNLEIMKRMLDDMDEKVEPCHNFYNSS-----QKN------LKWHAFATV-SDQFQLLFD 73
            :|.:.|.:.:...:|..:|..|:||.:|||.:     :||      .:|..|:.: .....::.:
Zfish    94 LCLSEPCVSVASAVLGSLDRSVDPCQDFYNFACGGWMRKNPLPEGKSRWGPFSNLWEHNMAVMKN 158

  Fly    74 GIENEVFEKHS-FEEKLQRLYKICSTMERPSLLRYFELVKPGEDL-----NWPFLTPRGGKWPKE 132
            .:||...:..| .|:|.|..|:.|....:...|.    .||.:||     .|..    .|.|.|:
Zfish   159 LLENTSMKSLSRAEQKAQWYYQACMNESKIEELG----AKPLQDLINQTGGWGL----KGPWEKD 215

  Fly   133 KFQWMEAL----ARLRRYGFNDIMFGMSIRQDPNSDSGQPIVVFEKKYDSLFRFIESLQNIGLPP 193
            .||  |.|    |..|...|    |.:.:..|..|.:...|.|.:             ..:|||.
Zfish   216 NFQ--EVLRIVSANFRTSPF----FTVFVSTDSKSSNSNIIQVDQ-------------SGLGLPS 261

  Fly   194 ------KLAKE----------------IAPLDNAIQEMYKSDMKFEHYARDAAPVKRISLGQLE- 235
                  |.|.|                :....:..|:|.:..:|||      ..:..|::.|:|
Zfish   262 REYYLNKTANEKYLNAYLNFLVELGVLLGGSQDTSQKMMEEIIKFE------TTLANITVPQVER 320

  Fly   236 -----IY-------------GVSLTKYLEIVFGRPF----SPDFVVHVENLYYLRGLQNLMTAVP 278
                 ||             .:....:|..||. |.    |...||:.:.  ||:.:..|::...
Zfish   321 RDEEKIYYKIQAKELATLAPAIDWMPFLSSVFA-PVELNDSEPVVVYAKE--YLQKVSELISNTN 382

  Fly   279 SQVVANYLTARFSFYIMFTFMKHGDSCVTTMRQSMEFASNLLFEERILGRKKLRSYQNQAGKIFD 343
            ..|:.||:           .||.....|:.:.|..:.|.. .|.|.:.|.||
Zfish   383 KSVLNNYM-----------IMKVVRKMVSILDQKFQDAEQ-RFLEVMYGTKK------------- 422

  Fly   344 AIRQQLNIRLERNVLKLPPAEISLLQKKLNGLSLSIGNLPGKA----GHRRFVTRYYKELEFADD 404
                           ...|.....:....:.|..::|.|..||    ..:.||.....|:::|.:
Zfish   423 ---------------SCMPRWKLCVSDTDSALGFALGALFVKATFSEDSKAFVEDMVSEIKWAFE 472

  Fly   405 EELATAH------LKVLEHRTRAELSLLDQPNF----KDRRYMLHSYP-ISNFFFETAYEENGNT 458
            :.|.|..      .|..:.:..|..:::..|.|    |:...:.:.:. :|:.:|:........:
Zfish   473 DSLKTVSWMDPETKKAAKEKADAIYNMVGYPKFIMNPKELDKVFNDFDVVSDLYFQNVMNYYNFS 537

  Fly   459 IYVAYDFL---------------ADASFDPDSHDIFKVTP---------------------LGIR 487
            ..|..|.|               .:|.::|..:::  |.|                     :|:.
Zfish   538 ARVTADQLRKAPNRDQWSMTPPTVNAYYNPTKNEM--VLPAGIFQAPFYNHAWPKAMNFGGIGVV 600

  Fly   488 FGLEMLKSFDLFNCKHHKVNMLQLFDDNQITTAGDECVSAWTQDN-----------LLSQRDQYL 541
            .|.|:..:||....|:.|       |.|         ::.|.|::           ::.|...|.
Zfish   601 MGHELTHAFDDQGRKYDK-------DGN---------LAKWWQNSSVEAFQHQTQCMVEQYSNYS 649

  Fly   542 V-------------------VLHLVHEAYFAEGSKFSQRQPNFTTMSL--RELFFFRFGQ 580
            :                   .|:..::|| ....|.:..:.:...:.:  .:|||..|.|
Zfish   650 INNEPLNGKHTLGENIADNGGLNAAYKAY-VNWIKKNGEEASLPALGMNNHQLFFVGFAQ 708

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl3	NP_608904.1	GluZincin	42..>434	CDD:472708	95/472 (20%)
ece1	NP_001071260.3	None