Protein Alignment Nepl3 and Nepl16

DIOPT Version :10

• Sequence 1: NP_608904.1
• Gene: Nepl3 / 326172
• FlyBaseID: FBgn0031678
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_001097912.1
• Gene: Nepl16 / 43014
• FlyBaseID: FBgn0039277
• Length: 752
• Species: Drosophila melanogaster
• Alignment Length: 739
• Identity: 139/739 - (18%)
• Similarity: 241/739 - (32%)
• Gaps: 263/739 - (35%)

  Fly    18 CSTVCSANPNLE--IMKRMLDDMDEKV----EPCHNF------YNSSQKNL-----KWHAFATVS 65
            ||...||.|...  |.:.:...:..::    :||..|      .|:..||:     ..::..:|.
  Fly   145 CSPAVSAPPECSDPICEAVASSIQARLNWNKDPCTEFKKFSCWRNTPNKNITNLIEMGNSQKSVD 209

  Fly    66 DQFQLLFDGIENEVFE------KHSFEEKLQR------LYKICSTME-------------RPSLL 105
            .|...||   :|::..      .:.||..||:      :::|..::.             .|.:.
  Fly   210 SQMLYLF---QNKIMNGSFGILHNLFESCLQQTTNSTVMHRIFDSLGGYLPVGSVGPSSIAPLIA 271

  Fly   106 RYFE-----LVKPGEDLNWPFLTPRGGKWP----------------KEKFQWMEALA---RLRRY 146
            :.::     ||....||::       |:.|                :.|.:||...|   |:|:
  Fly   272 KIYDLGPSPLVDLYHDLSY-------GRRPHILLIISGPSTSSTILERKIRWMSPKAPPSRIRQ- 328

  Fly   147 GF---------NDIMFGMSIRQDPNSDSGQPIVVFEKKYDSLFRFIESLQNIGLPPKLAKEIAPL 202
            |.         |.:.:.:|..|.          |.||  |::|.||:.|
  Fly   329 GVPKLLADLIENFLPYFVSYAQR----------VSEK--DTIFEFIKDL---------------- 365

  Fly   203 DNAIQEMYKSDMKFEHYAR---DAAPVKRISLGQLEIYGV-SLTKYLEIVFGRPFSPDFVVHVEN 263
                     :.::.||..|   |:..:..:|..| ::|.| :.|..:...:..|      :.|.|
  Fly   366 ---------NKLQVEHSRRGFWDSTVLYNVSSLQ-DLYPVLNWTLLIPQNWSGP------IVVRN 414

  Fly   264 LYYLRGLQNLMTAVPSQVVANYLTARFSFYIMFTFMKHGDSCV-TTMRQSMEFASNLLFEERILG 327
            ..||:.|:..:|..|::|..|.|....:..|:.......:.|. :||....|.:|:|...:.  .
  Fly   415 SDYLKALEYFLTKYPTRVAHNSLLLLSALQILPRDYPSPEVCTRSTMWALPELSSSLYIAQH--S 477

  Fly   328 RKKLRSYQNQAGKIFDAIRQQLNIRLERNVLKLPPAEISLLQKKLNGLSLSIGNLPGKAGHRRFV 392
            .:.|:....:|..||.:::..         ||..|:.......||:.|.:......|
  Fly   478 SEDLKDTTKRAEIIFKSLKAH---------LKRAPSLKGAALVKLSALKIQSQTWEG-------- 525

  Fly   393 TRYYKELEFADDEELATAHLKVLEHRTRAELSLLDQPNFKDRRYMLHSYPISNFFFETAYEEN-- 455
                    |::..:|    ||.|:     .|::..:..|::         |...:.:...|.|
  Fly   526 --------FSNTTDL----LKSLQ-----PLNITSECWFQN---------ILEIYKKNKLEPNDI 564

  Fly   456 ----GNTIYVAYDFLADASFDPDSHDIFKVTPL---------------------GIRFGLEML-- 493
                |:....||..::...:|..||.|  |.||                     |:....|:|
  Fly   565 SLNGGSHDAWAYPIVSTIFYDTLSHSI--VVPLSVILIPYFNAVLPPYLHYASVGVSIAKEILRS 627

  Fly   494 --KSFD--LFNCKHHKVNMLQLFD--DNQITTAGDECVSAWTQDNLLSQRDQYLVVLHLVHEAYF 552
              ||||  ...|..|.||:...:.  |..|.:.|              .:..|..:|.|....
  Fly   628 ITKSFDEKAMRCVPHSVNIFSNYSRMDILIHSGG--------------MQISYHSMLSLTGPI-- 676

  Fly   553 AEGSKFSQRQPNFTTMSLRELFFFRFGQSSFGQTLYFGSD-------------FVEGGSPINSLT 604
                |...|.|.. .::..::||....|....::.|.|.|             ..:|||.
  Fly   677 ----KGMARLPGL-NLTPTQIFFLVSAQELCAESNYLGIDTNAPEFDNILGWLVAQGGSA----- 731

  Fly   605 RLPVFVRTFNCLAPGEQLTTTQKS 628
                 ...|.|  |...:...||:
  Fly   732 -----TEVFKC--PSGSMINVQKT 748

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl3	NP_608904.1	GluZincin	42..>434	CDD:472708	86/469 (18%)
Nepl16	NP_001097912.1	GluZincin	176..750	CDD:472708	133/708 (19%)