Protein Alignment Nepl3 and Nepl14

DIOPT Version :9

• Sequence 1: NP_608904.1
• Gene: Nepl3 / 326172
• FlyBaseID: FBgn0031678
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_651097.1
• Gene: Nepl14 / 42700
• FlyBaseID: FBgn0039023
• Length: 696
• Species: Drosophila melanogaster
• Alignment Length: 766
• Identity: 150/766 - (19%)
• Similarity: 251/766 - (32%)
• Gaps: 251/766 - (32%)

  Fly     7 YLSLSWLLLLLCSTVCSAN---PNLE--------IMKRMLDDM----DEKVEPCHNFYNSSQKNL 56
            :|.|.||..|..:.:.|..   |..:        :.:....||    ::.::||.:||..:..|
  Fly    10 FLWLLWLPHLQQNALVSGEDLPPPFQRIYQSEQTVRRSKAQDMGSHVNKSIDPCVDFYAYACGN- 73

  Fly    57 KWHAFATVSDQFQLLFDG-----IENEVFEKHS-FEEKLQRLYKICSTMERPSLLRYFELVKPGE 115
             |.:..|...|.|...|.     :|..|..:.| ...:.:.|:|.|.:.:.....:....:....
  Fly    74 -WKSTLTPQQQLQQQTDRELLLLVEEAVRREDSVIVRQAKELFKSCVSAQAHQSQQQQHFLSEFI 137

  Fly   116 DLNWPFLTPRGGKWP--KEKFQWMEALARLR-RYGFNDIMFGMSIRQ---DPNSDS---GQPIVV 171
            :.|..|....|.:|.  ...:.|:..|..|| |||. ||:.|:.:..   :.|.:|   .:|..:
  Fly   138 NQNGGFPAVPGSQWAVHHHDYNWLSVLGGLRLRYGM-DILIGLRVGYNYGNVNENSLYLSEPSTL 201

  Fly   172 FEKKY---------DSLFRFIESLQNIGLPPKLAKEIAPLDNAIQEMYKSDMKFEH--YARDAAP 225
            ...:.         ||::.                   ||::.:....||.:...|  .||.||.
  Fly   202 IPTELCTRNRSDIRDSIYE-------------------PLEHRVASELKSWLALGHDESARLAAD 247

  Fly   226 VKRISL----------GQLEIYG-----------------------VSLTKYLEIVFGRP-FSPD 256
            :  :|.          |..|.:.                       :.|..|:...||:. :.|.
  Fly   248 I--LSFEHELCGGMKGGSFESWDAEEQLYLANYTRKTLREFSNSIELDLDSYVRASFGQDIYKPV 310

  Fly   257 FVVHVENLYYLRGLQNLMTAVPSQVVANYLTARFSFYIMFTFMKHGDSCVTTMRQSMEFASNLLF 321
            ::...|   |.|.|:..::|....:||||:..|....:.|..   .|......|:.:|....||
  Fly   311 YMAAPE---YFRQLKRTVSAHNISLVANYIMYRAVSALNFPL---DDRPQLRKRECLERTKELL- 368

  Fly   322 EERILGRKKLRSYQNQAGKI-----FD----AIRQQLNI-------------RLERNVLKLPPAE 364
             ...||....|.:..:.|:|     :|    |:||.|..             :|....|::|..|
  Fly   369 -PTALGELYARQFGTEDGRIDLDNLYDTLKTALRQSLGAEWLVEGTQRVGQEKLRNLKLQMPTYE 432

  Fly   365 ISLLQKKLNGLSLSIGN-------LPGKAGHRRFVTRYYKELEFADDEEL----ATAHLKVLEHR 418
            ..::.|    |.|..||       |.|....:| ..|.::|...|..:.:    |...|:.::.|
  Fly   433 RPVILK----LQLERGNYWQNLRQLLGVVQSQR-NNRLFEEFLPAPTDPVEAYEARVRLRPVQRR 492

  Fly   419 TRAELSLLDQPNFKDRRYMLHSYPISNFFFETAYEENGNTIYVAYDFLADASFDPDSHDIFKVTP 483
            ....|:||..|                                        ::||......:...
  Fly   493 LDMGLALLQPP----------------------------------------AYDPRYGHAIRYAT 517

  Fly   484 LGIRFGLEMLKSFDLFNCKHHKVNMLQLFD-DNQITTAGDECVSAW---TQDNLLS-QRDQYL-- 541
            ||::...:::.:||   ..|..|.:|:..: |.|         :||   .:.|..: |.|.||
  Fly   518 LGVQLAQQLVMAFD---DPHWSVGLLERDNWDGQ---------TAWQYHIRSNCFARQVDNYLRP 570

  Fly   542 ------------VVLHLVHEAYFAEGSKFSQRQPN--FTTM----------SLRELFFFRFGQSS 582
                        ..:::...||.   :....::||  ||.:          |...|||..:.|..
  Fly   571 NVSATTQLITDSAAINVAFRAYL---TWLGFQEPNNDFTKLTKETLPDLNYSNTALFFLAYAQEH 632

  Fly   583 FGQTLYFGSDFVEGGSPINSL---------TRLPV---------FVRTFNC 615
            .  :|.......|.|:|...|         |||.|         |...|.|
  Fly   633 C--SLEEARPRDEQGTPEGYLYSARQNHTWTRLLVNGPLRNSVEFASEFRC 681

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl3	NP_608904.1	GluZincin	42..581	CDD:301352	128/662 (19%)
Nepl14	NP_651097.1	M13	60..693	CDD:189000	141/716 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45454874
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740