Protein Alignment Nepl3 and Nepl13

DIOPT Version :10

• Sequence 1: NP_608904.1
• Gene: Nepl3 / 326172
• FlyBaseID: FBgn0031678
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_651096.1
• Gene: Nepl13 / 42699
• FlyBaseID: FBgn0039022
• Length: 741
• Species: Drosophila melanogaster
• Alignment Length: 790
• Identity: 149/790 - (18%)
• Similarity: 270/790 - (34%)
• Gaps: 244/790 - (30%)

  Fly     1 MMESRSYLSLSW------LLLL----LCSTVCSANPN----LEIMKRMLDDMDEKV--------- 42
            |..:||    :|      ||||    ||. |..|..|    :::.....|..:|::
  Fly     1 MRATRS----AWLGFLLELLLLFEIQLCD-VTEARQNHMNRMQMSGNFPDSREEQLVRQKIATDV 60

  Fly    43 --------EPCHNFYNSS--------QKNLKWHAFAT--------VSDQFQLLFDGIENEVFEKH 83
                    :||.:|:..:        ::.|:....:|        :|:|.|.|   :...:..:|
  Fly    61 QKYMNLSADPCTDFFEYACGQWGRYHKRQLRPDELSTAQQLMETKISEQLQQL---LTQPLPPQH 122

  Fly    84 ----------SFEEKLQRLYKICSTMERPSLLRYFELVKPGEDLNWPFLTPRGG-------KWPK 131
                      :...|::..|:.|..:|..:..|...|:|        .|...||       .|..
  Fly   123 HPNGYSGASMTNVRKVRAFYESCVAVEANASERRRFLMK--------ILKDNGGLRNVPNSNWQH 179

  Fly   132 EKFQWMEALARLRR-YGFNDIMFGMSIRQDPNSDSGQPIVVFEKKY------------------- 176
            .: ||::.|..||| ||. ||:.|:.|..:..:..|..|...|.|.
  Fly   180 NR-QWVQTLGELRRNYGL-DILLGLEIDLNLQTMKGNTIYFGEPKLTIIPAEHCNALATRGAQVR 242

  Fly   177 DSLFRFI-----ESLQ-----NIGLPPKLAKEIAPLDNAI------QEMYKSDMKFEHYARDAAP 225
            |.::..:     |:|:     :.|...:.|.:|...:..:      |::.|.:.:|....:....
  Fly   243 DEVYELVQQQVTENLRDWFGMDTGEAARFAGDIIRFEFELCKQMGEQDIQKPEEEFPPAIQAQIY 307

  Fly   226 VKRISLGQLEIY----GVSLTKYLEIVFGRPFSPDFVVHV--ENLY----YLRGLQNLMTAVPSQ 280
            ..|...||..:.    |::||: |....|.......:|.|  |:.|    |||..:.:...|.:.
  Fly   308 GARSRTGQERLRRQKGGMTLTE-LTSEMGNHLDFKMLVEVILESQYPSQVYLRSPEYVKHVVRTV 371

  Fly   281 VVANYLTARFSFYIMFTFMKH-----GDSCVTTMRQSMEFASNLLFEERILGRKKLRSYQNQAGK 340
            ...|.:|.  ..||::..:..     .::.....||.::....|.  .::||....|..|....|
  Fly   372 KANNRITV--GGYILYVALNELNQPPEEAPSQRARQCVQVTQRLF--PQVLGEMFQRHVQRDNAK 432

  Fly   341 ---------IFDAIRQQLNIR-LERNVLKLPPAEISLLQKKL-NGLSLSIGNLPGKAGHRRFVTR 394
                     :..|:.:|.::. ::.|..:.....:|..:..| :..||.:.:|..:...     .
  Fly   433 HDLDAVFNDVIKALEEQFHVEWMDENDRRAARTRLSQYRVSLPDYQSLDLTDLQFQKSE-----D 492

  Fly   395 YYKELEFADDEELATAHLKVLEHRTRAELSLLDQPNFKDRRYMLHSYPISNFFFETAYEENGNTI 459
            |::.||.|            |::|:..:...|...:|......|.::.:     ..|.......:
  Fly   493 YWRRLEIA------------LKYRSHQQFEALRGNDFGQDADGLDAFEV-----RAALSPRQQMV 540

  Fly   460 YVAYDFLADASFD---PDSHDIFKVTPLGIRFGLEMLKSFDLFNCKHHKVNMLQLFDDNQITTAG 521
            .|.:..|....::   |.|   .|...||.|....::::||.....:|.....|.   |::|.:|
  Fly   541 LVGWGLLQAPYYNYYYPKS---LKYALLGHRLASALVQAFDDEGWNNHPQATAQW---NEVTMSG 599

  Fly   522 ----DECVSAWTQDNLLSQRDQY--------LVV----LHLVHEAYFA--EG---------SKFS 559
                .||..|.....|.::..::        ::.    |:|...||.|  |.         :|.:
  Fly   600 YRNASECQRAQYSSYLYNEPGEFRNATRLREIIADGSGLNLAFNAYLAWLEQQDHKLRPLLAKET 664

  Fly   560 QRQPNFTTMSLRELFFFRFGQS-----------------------------SFGQTLYFGSDFVE 595
            ..:.|||.   .:|||..|.|:                             ....:..||.:|
  Fly   665 LSELNFTN---TQLFFIYFAQTRCWAKDNQDAILDSMPLMQHTPERWDVNGPLSNSAEFGREF-- 724

  Fly   596 G---GSPINS 602
            |   |:|:||
  Fly   725 GCALGTPMNS 734

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl3	NP_608904.1	GluZincin	42..>434	CDD:472708	90/503 (18%)
Nepl13	NP_651096.1	M13	68..738	CDD:341056	134/718 (19%)