Protein Alignment Nepl3 and Nepl10

DIOPT Version :10

• Sequence 1: NP_608904.1
• Gene: Nepl3 / 326172
• FlyBaseID: FBgn0031678
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_610787.1
• Gene: Nepl10 / 36366
• FlyBaseID: FBgn0033742
• Length: 633
• Species: Drosophila melanogaster
• Alignment Length: 684
• Identity: 148/684 - (21%)
• Similarity: 260/684 - (38%)
• Gaps: 161/684 - (23%)

  Fly    14 LLLLCSTVCS--------ANPNLEIMKRMLDDMDEKVEPCHNFYN-------SSQKNLKWHAFAT 63
            ||||||.:.:        .:.|:.....:.::::....||.||:|       |:.|.:  ..|..
  Fly     4 LLLLCSCLVALFIPIQAIVDINVATSNDIHNNLNRTTSPCTNFWNFACGRFSSASKYV--DNFER 66

  Fly    64 VSDQF-QLLFDGIENEVFEKHSFEEKL----QRLYKICSTMERPSLLRYFELVKPGEDLNWPFLT 123
            |.||| ..:.:.:|:.:.|..:...:|    ::.||.|.                 ||.......
  Fly    67 VEDQFATAMVEFMESHLGENDTLAPRLIKQMRQYYKACK-----------------EDTRKLHGN 114

  Fly   124 PRGGKWPKEKF-QWMEALARLRRYGFN--------DIMFGMSIR-------QDP-NSDSGQPIVV 171
            ||    |:|.. ||:....:...||.|        |:....|:|       .|| :..|.:.::.
  Fly   115 PR----PEELVNQWILHPKKFLVYGLNGVFIDERVDVAANDSMRWVIQLRMPDPADRYSDRRVLQ 175

  Fly   172 FEKKYDSLFRFIESLQNIGLPPKLAKEIAPLDNAIQEMYKSDMKFEH-----YARDAAPVKRISL 231
            ..:.|:      |:..::|: .||.:::    :.:|:.|:::....:     ..|...|:.....
  Fly   176 LMRLYE------EAWYSMGV-VKLVEKM----HQLQDKYRAEYPVVYTWSFSELRQEIPIPHSFF 229

  Fly   232 GQLEIYGVSLTKYL-EIVFGRPFSPDFVVHVENLYYLRGLQNLMTAVPSQVVANYLTARFSFYIM 295
              :|:.||:.|:.| .:.|          .|.::.|||.....:....|:....|:.||     .
  Fly   230 --IELLGVNHTEELYHLTF----------EVSDVEYLRECFRCLRDFASEPKDTYIRAR-----Q 277

  Fly   296 FTFMKHGD-------SCVTTMRQSMEFASNLLFEERILGRKKLRSYQNQAG------KIFDAIRQ 347
            :..::..:       ||:..||..:....|.:::..|        |||:..      :|...::.
  Fly   278 YVLVEESEPRERNPRSCIHHMRAYLPLGMNYIYDRFI--------YQNREEDTSKVLEILSTLKA 334

  Fly   348 QLNIRLERNVLKLPPAEISLLQKKLNGLSLSIGNLPGKAGHRRFVTRYYKELEFADDEELATAHL 412
            .....|:.|.|:|.|.:::.::.||.|:.:.|||||.:.. ..|...:|....|:....||.. |
  Fly   335 AFGQYLDANRLQLTPNQLAYVRAKLEGIQIKIGNLPEEKS-PEFYNNHYGSANFSATNFLANL-L 397

  Fly   413 KVLEHRTRAE-LSLLDQPNFKDRRYMLHSYPISNFFFETAYEENGNTIYVAYDFLADASFDPDSH 476
            :....|||.: ..||.:.:..|.|:...:..:........||...|||.|..:||....||...|
  Fly   398 EAFALRTRLQNAGLLARNSRVDLRHYYVNDNVRKARTSPFYENERNTITVPMEFLQWPLFDHREH 462

  Fly   477 DIFKVTPLGIRFGLEMLKSFDLFNCKHHKVNMLQLFDDNQITTAGDE---------------CVS 526
            .||:.:.||...|.||..:|:....         |||     .||:|               .:.
  Fly   463 TIFQHSLLGAVLGHEMNHAFEQEGI---------LFD-----AAGNESPVGLEIRESKPFRDAIK 513

  Fly   527 AWTQDNLLSQRDQY--LVVLHLVHEAYFA---EGSKFSQR----QPNFTTMSLRELFFFRFGQSS 582
            ...:...:|.:::.  |..|.|.::|:|.   :..:|..|    :..||...|..|.:.:|...|
  Fly   514 CAEEQPFVSLKERLADLNGLQLAYDAFFGLAHDSRQFEYRPYAFEQEFTAPQLFHLSYAQFFCGS 578

  Fly   583 FGQTLYFGSDFVEGGSPIN-SLTRLPVFVRTFNC 615
            ....:....|    ...:| |:..|..|...|||
  Fly   579 LPPVIAHDRD----DERVNVSVGNLRQFAYDFNC 608

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl3	NP_608904.1	GluZincin	42..>434	CDD:472708	92/440 (21%)
Nepl10	NP_610787.1	GluZincin	41..608	CDD:472708	139/645 (22%)