Protein Alignment Nepl3 and Nepl9

DIOPT Version :9

• Sequence 1: NP_608904.1
• Gene: Nepl3 / 326172
• FlyBaseID: FBgn0031678
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_609815.1
• Gene: Nepl9 / 35020
• FlyBaseID: FBgn0032613
• Length: 652
• Species: Drosophila melanogaster
• Alignment Length: 691
• Identity: 131/691 - (18%)
• Similarity: 231/691 - (33%)
• Gaps: 211/691 - (30%)

  Fly    27 NLEIMKRMLDDMDEKVEPCHNFY--------NSSQKNLKWHAFATVSDQF--QLLFDGIENEVF- 80
            ||:.:.::.:|   .::||.:||        .:.::|         ||.|  ..|::..:...|
  Fly    49 NLQQLVKIKND---SMDPCDDFYAHACGNFDQTKEEN---------SDDFLPPYLYNKQDRMNFF 101

  Fly    81 --EKHSFE----EKLQRLYKICSTMER--------------------PSLLRYFELVKPGEDLNW 119
              |..:||    ..:.:||..|...|.                    |.|.|:.|::.     :|
  Fly   102 TAEVGNFETIPGRLISQLYTECRKREERNVFTPTRLTSHWERMLDEIPFLARHKEVLS-----SW 161

  Fly   120 PFLTPRGGKWPKEK----FQWMEALARLRRYGFNDIM---FGM-SIRQDPNSDSGQPIV------ 170
            |||.   .:|.:.:    ..|:...|:|..:|...::   |.: :|...|..:...|.:
  Fly   162 PFLK---HQWERRRLYGQLNWIVLSAQLAAHGLPTLLHIYFALDTIYVSPMEELPCPSIADFQSS 223

  Fly   171 ---VFEKKYDSLFRFIESLQNIGLPPKLAKEI---APLDNAIQEMYKSDMKFEHYARDAAPVKRI 229
               |.|.::..:.|.|.....:     |.:|:   .||..::.:..:::.  .....:...:...
  Fly   224 LSDVLEGRHHQVSRIISHEMRV-----LCREMRGELPLVRSLSQNTRTNT--SRPGEEQLLLDEN 281

  Fly   230 SLGQLEIYGVSLTKYLEIVFGRPFSPDFVVHVENLYYLRGLQNLMTAVPSQVVANYL--TARFSF 292
            ::...:.|..:|....|.:.|   :..|.:.||.   :.....::....:::|.||:  .||..
  Fly   282 TMDYFQQYFAALNFSEERLVG---ARKFPLDVEK---ITQAWEVLRHTETRIVYNYVMWQAREQ- 339

  Fly   293 YIMFTFMKHGDSCVTTMRQSMEFASNLLFEE--------RILGRK-KLRSYQNQAGKIFDAIRQQ 348
                  :::.| |   .|.|.|| ..||..|        |.|.|: .|.|||....:.....|.:
  Fly   340 ------LRYPD-C---YRVSEEF-ERLLHAEYWQWHVLRRHLSREVALASYQLHTTRFQKLRRSK 393

  Fly   349 LNIR----------LERNVLKLP-----PAE----ISLLQKKLNGLSLS----IGNL----PGKA 386
            |:.|          :|:..|::.     .||    |:.|.:...||.|.    ..||    ..:.
  Fly   394 LSRRDWYGHLWPASVEKKELQVARILQNHAENYLNITELNENYEGLKLEKNSFYANLLILRRAQL 458

  Fly   387 GHRRFVTRYYKELEFADDEELATAHLKVLEHRTRAELSLLDQPNFKDRRYMLHSYPI---SNFFF 448
            .| .||:.|.       |||........|.|.....|..|.:|.:  ..|..|...:   |....
  Fly   459 RH-SFVSPYV-------DEEDVNQPAYFLRHFLHFVLLSLHRPTY--HYYATHGLELWRESRLLL 513

  Fly   449 ETAYEENGNTIYVAYDFLADASFDPDSHDIFKVTPLGIRFGLEMLKSFDLFNCKHHKVNMLQLFD 513
            :|    :|:  |.|.|.|...||   .|...|:.|:....|            .|....:.|.:.
  Fly   514 DT----DGH--YTAMDCLERQSF---QHYDAKLAPIYRPLG------------SHEIAEIFQFYR 557

  Fly   514 DNQITTAGDECVSAWTQDNLLSQRDQYLVVLHLVHEAYFAEGSKFSQRQP---NFTTMSLRELFF 575
            ..|.:                           |....::.:|.:|:..:.   ::..::...:.|
  Fly   558 SFQYS---------------------------LTDYHFWLQGERFAFAETFVLDYFGLNPHRVLF 595

  Fly   576 FRFGQSSFG-QTLYFGSDFVEGGSPINSLTRLPVFVRTFNC 615
            :...|.... ||..|.:....|      ...||.|...|.|
  Fly   596 YAVAQQLCNRQTEIFAAQLNRG------YMNLPEFQEAFKC 630

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl3	NP_608904.1	GluZincin	42..581	CDD:301352	118/639 (18%)
Nepl9	NP_609815.1	GluZincin	62..>84	CDD:301352	5/30 (17%)
		GluZincin	<579..642	CDD:301352	11/58 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45454968
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.830