Protein Alignment Nepl3 and Nepl7

DIOPT Version :10

• Sequence 1: NP_608904.1
• Gene: Nepl3 / 326172
• FlyBaseID: FBgn0031678
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_609577.2
• Gene: Nepl7 / 34671
• FlyBaseID: FBgn0032442
• Length: 669
• Species: Drosophila melanogaster
• Alignment Length: 756
• Identity: 141/756 - (18%)
• Similarity: 243/756 - (32%)
• Gaps: 259/756 - (34%)

  Fly     8 LSLSWLLLLLCSTVCSANPNLEIMKRMLDD--------MDEKVEPCHNFY--------------- 49
            :||:.:..:|.:.:.|..|.....:.||:|        |:..::||.|||
  Fly    10 ISLTLIGRVLANDLFSLPPATNHREEMLEDYGRFLLSTMNRTIDPCENFYEFSCGGWKKADLVPE 74

  Fly    50 ---NSSQKNLKWHAFATVSDQFQ-LLFDGIENEVFE-----KHSFEEKLQRLYKICSTMERPSLL 105
               |:|..|...|   .:.:|.| .|.:..:.|:.:     ..|.|.|.::.|..|..|
  Fly    75 QARNTSFLNAIQH---KIDEQIQGFLQNATKRELEDLGVNGTTSAEIKAKQFYASCVEM------ 130

  Fly   106 RYFELVKPGEDLNWPFLTPRGGKWPKEK---FQWM-----------EALARLRRYGFND------ 150
                  |....|.:.:.....|...||:   :.||           ..||....|..:.
  Fly   131 ------KANLSLGYQYFMEHDGDRLKERNATYDWMYINFMSKYDIYPLLALKVHYSTSSRKFDIL 189

  Fly   151 ------IMFGMSIRQDPN-------SDSGQPIVVFEKKYDSLFRFIESLQNIGLPPKLAKEIAPL 202
                  ::.|.|..|..|       ..|.:.:..|.:.:::|.:|..:|.:      |||.
  Fly   190 LTLPSKVLAGFSEEQLKNMTREFGLDSSAEKVKQFVENFNNLTQFERNLVS------LAKS---- 244

  Fly   203 DNAIQEMYKSDMKFEHYARDAAPVKRISLGQLEIYGVSLTKYLEIVFGRPFSPDFVV-----HVE 262
            .|..:::...:...:| ..|.               ::.|::.|:.|.......:.|     ::.
  Fly   245 RNETEQLNFKEFLVKH-KHDR---------------LNWTRFFELAFNGSQESHWPVLNQLDNIN 293

  Fly   263 NLYYLRGLQNLMTAVPSQVVANYLTAR--FSFYIMF-TFMKHG---DSCVTTMRQSMEFASNLLF 321
            :|.:.....||.|      :..|:..|  ..||.:: |..|.|   ..|
  Fly   294 DLVFFLEQTNLET------LKGYIKMRELVKFYGLWKTQTKTGGVQSEC---------------- 336

  Fly   322 EERILGRKKLRSYQNQA------GKIFDAIRQQLNIRLERNVLK-----------LPPAEISLLQ 369
                  |....:|.|.|      ||:||..|:...:.:.:::..           |.....|..:
  Fly   337 ------RSLSETYFNYALLPWFIGKVFDKERRADILSVAKDIKDTFYDLLDHHTWLDEDTRSQAK 395

  Fly   370 KKLNGLSLSIGNLPGKAGHRRFVTRYYKELEFADD--EELATAHLKVLE-HRTRAELSLLDQ--- 428
            .||..:.:.:| ......||..:...|.::....:  |.|.     :|| .|.|..|..:|:
  Fly   396 TKLASMDILVG-YTDDLQHREVIDGVYSDINMTGNWFENLC-----ILEGSRARIRLRSVDKALI 454

  Fly   429 PNFKDRRYMLHSYPISNFFFETAYEENGNTIYVAYDFLADASFDPDSHDIFKVTPLGIRFGLEML 493
            |.....| .:::|          |.:..|..::.........:..|..|:.|...:|...|.||.
  Fly   455 PLLMPTR-TVNAY----------YADFLNLAFITIGMAQWPFYHIDFPDVLKYAGVGNIIGHEMA 508

  Fly   494 KSFD--------------------------LFNCKHHKVN--MLQLFDDNQITTAGDECVSAWTQ 530
            ..||                          .:.|...:.|  :|.....|...|:||...
  Fly   509 HGFDSYCYQYNYDGKKTNWWSSASLRNFKERYRCLESQYNKFILMGVQTNGSLTSGDNIA----- 568

  Fly   531 DNLLSQRDQYLVVLHLVHEAYFA----EGSKFSQRQP----NFTTMSLRELFFFRFGQS-----S 582
            ||:.::.            ||:|    .|.|....:|    ||..   ::|||.:|.|:     .
  Fly   569 DNVGTRM------------AYYAFKRKTGDKAWLEKPLRGVNFNN---KQLFFVKFAQTWCNGKD 618

  Fly   583 FGQTL-------YFGSDF-VEGGSPINSLTRLPVFVRTFNC 615
            .|..|       :...:| |:|     :|:.:|.|...|||
  Fly   619 NGDKLRRLKTDVHAYDEFRVQG-----TLSNMPEFSEAFNC 654

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl3	NP_608904.1	GluZincin	42..>434	CDD:472708	86/482 (18%)
Nepl7	NP_609577.2	M13	52..666	CDD:341056	132/714 (18%)