Protein Alignment Nepl3 and Nepl6

DIOPT Version :9

• Sequence 1: NP_608904.1
• Gene: Nepl3 / 326172
• FlyBaseID: FBgn0031678
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_609023.3
• Gene: Nepl6 / 33893
• FlyBaseID: FBgn0259716
• Length: 655
• Species: Drosophila melanogaster
• Alignment Length: 696
• Identity: 199/696 - (28%)
• Similarity: 312/696 - (44%)
• Gaps: 135/696 - (19%)

  Fly    12 WLL-LLLCSTVCS--------ANPNLEIMKRMLDDMDEKVEPCHNFYNSSQKNLKWHAFATVSDQ 67
            ||: .|....:|:        |:||..:|..:|..:.|....|..::   |.....:|.....|.
  Fly     2 WLIACLFIVPICAAPTTQNVEADPNSRLMNNILSYVAEDSSACGTYF---QYACGKYAVRHRDDP 63

  Fly    68 FQLLFDGIENEV-------------------FEKHSFEEKLQRLYKICSTMERPSLLR----YFE 109
            |..:...::::|                   |.:.|.|.|:...|:.|  .|.|...|    |..
  Fly    64 FTEIIQMLDHKVNGNLVQLMHELHQRSQSPGFNESSVEAKVLHFYRTC--REAPPSTRKMEHYLR 126

  Fly   110 LVKPGEDLNWPFLTPRGGKWPKEKFQWMEALARLRRYGFNDIMFG-MSIRQDPNS-----DSGQP 168
            |..||:.|.||...|||..|||.:|:||::|..|.||||.:::.. :.:|...||     |...|
  Fly   127 LAPPGQALTWPQFMPRGEPWPKAQFKWMKSLGHLYRYGFTNVLVNVLVLRSSENSNRFRLDISMP 191

  Fly   169 IVVFEKKY-DSLFRFIESLQNIGLPPK----LAKEIAPLDNAIQEMYKSDMKFEHYARDAAPVKR 228
            .:..:.:: ......:.:||.||:|.|    |.::|..|::||:.:.:.|        |....:.
  Fly   192 SLEGDAQHLGGFLSTLATLQIIGVPTKSILPLVRKIRRLESAIRVLTEVD--------DDDESET 248

  Fly   229 ISLGQLEI-YGVSLTKYLEIVFGRPFSPDFVVHVENLYYLRGLQNLMTAVPSQVVANYLTARFSF 292
            .:|.|.|. .|.:...::|.:.|...|..:|:..:|..|..||:.||.:..::|||||:..||..
  Fly   249 WTLRQWEYKTGYAWQGFVESIVGHSVSHHYVMQAQNAKYFTGLKRLMDSTDAEVVANYIMTRFVL 313

  Fly   293 YIMFTFM---KHGDSCVTTMRQSMEFASNLLFEERILGRKKLRSYQNQAGKIFDAIRQQLNIRLE 354
            |::..|:   :|.| |||.||::|..|||||::||.|....|:.|..:..|:|:.:|:|..:::.
  Fly   314 YLIDDFIDSNEHID-CVTDMRRNMNLASNLLYKERFLDPATLQQYTQEVTKVFEQLRRQFLLQIN 377

  Fly   355 RNVLKLPPAEISLLQKKLNGLSLSIGNLPGKAGHRRFVTRYYKELEF-ADDEELATAHLKVLEHR 418
            .|.|.|...:.|::..|...:.|:|||||....||.||:|:|::|.| ..|.:.|..||.:||.|
  Fly   378 ENRLGLTSEQNSMVATKAQHVVLNIGNLPRGRDHRSFVSRHYEDLVFPLPDFDYAREHLNLLEFR 442

  Fly   419 TRAELSLLDQPNFKDRRYMLHSYPISNFFF-----ETA------YEENGNTIYVAYDFLADASFD 472
            ||.::..|:|           |.|..:.||     :||      |....|.|.|.:..|.:..|.
  Fly   443 TRKQVLQLNQ-----------SAPTPDEFFYLSDPKTAMSSGPYYLMRLNIIVVPHGLLQEPFFA 496

  Fly   473 PDSHDIFKVTPLGIRFGLEMLKSFDLFNCKHHKVNMLQLFDDN---------QITT-----AGDE 523
            .|||||||.:.||.....|::          |.|:.:.|:.|.         ||::     ||.:
  Fly   497 ADSHDIFKYSLLGFVLAHELM----------HSVDTVGLYYDRYGNIHEIGPQISSSPRFVAGLQ 551

  Fly   524 CVSAWTQDNLLSQRDQYLVVLHLVHEAYFAEGSKFSQRQPNFTTMSLRELFFFRFGQSSFGQTLY 588
            |::. .....|.:|...:..|.|.:..||...|:.|  ..:|||:..:::||....|       :
  Fly   552 CLNR-NSTQYLDERIADIAGLDLAYSTYFQNSSQMS--LTDFTTIPPQQIFFLNLAQ-------F 606

  Fly   589 FGSDFVEGGSPINSL------TRL-------PVFVRTFNCLAPGEQ 621
            |..|    |.|||.:      |||       ..|...|.|.|...|
  Fly   607 FCGD----GDPINFVGHDNDETRLQQMLNGFAPFHEAFGCPAKSNQ 648

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl3	NP_608904.1	GluZincin	42..581	CDD:301352	174/602 (29%)
Nepl6	NP_609023.3	M13	42..653	CDD:189000	189/656 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45454858
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006719
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.740