Protein Alignment Nepl3 and Nepl5

DIOPT Version :9

• Sequence 1: NP_608904.1
• Gene: Nepl3 / 326172
• FlyBaseID: FBgn0031678
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_609022.1
• Gene: Nepl5 / 33892
• FlyBaseID: FBgn0031808
• Length: 684
• Species: Drosophila melanogaster
• Alignment Length: 717
• Identity: 154/717 - (21%)
• Similarity: 271/717 - (37%)
• Gaps: 160/717 - (22%)

  Fly     8 LSL-SWLLLLLC----STVCSANPNLEIMKRMLDD-----MDEKVEPCHNFY----------NSS 52
            ||| :||:..|.    .|.|......:.::.||.:     ||.|..||.|||          ...
  Fly     4 LSLVAWLIFSLAWRTTPTACRQTNAPQSVQEMLAEQLQSYMDTKARPCENFYQYACGNWQIQQQE 68

  Fly    53 QKNLK---W---------------------HAFATVSDQFQLLFDGIENEVFEK-HSFEEKLQRL 92
            |.:|:   |                     |   :|:.:.:||........||. .|..|:::..
  Fly    69 QHSLRDRDWTRDRQRYQGQMLPTDTLGLIDH---SVNRKLELLLRRRNESSFESDSSILEQMRLY 130

  Fly    93 YKICSTMERPSLLRYFELVKPGEDLNWPFLTPRGGKWPKEKFQWMEALARLRRYGFNDIMFGMSI 157
            |:.|..::..:|.:|.:|:.|.....||.:   |..|..|:|.|:..|.|||.:|.|    |:.:
  Fly   131 YRSCKRLKPYNLKKYLQLLPPSNSTQWPSV---GRGWRPERFDWITTLGRLRLHGLN----GVLL 188

  Fly   158 RQD--PNSDSGQPIVVFEKKYD-------SLFRFIESLQNIGLPPKLAKEIAPLDNAIQEMYKSD 213
            |::  |..|..:...::..|..       .....||.|.:||...:.|..:|   ..:.:..:..
  Fly   189 REEVLPRWDDSRNYSIYVNKPSRQETQPMGEGAMIELLLDIGQTKRTANALA---RQVDDFERKL 250

  Fly   214 MKFEHYARDAAPVKRISLGQLEIYGVSLTKYLEIVFGRPFSPD------FVVHVENLYYLRGLQN 272
            .:.:....|..| :.:.||.|:.|   |.:...:.|.|....|      ..:.:||:.|||.|.:
  Fly   251 HRLQELEDDEGP-REMQLGYLDSY---LPQLRWLSFMRQVRIDSELDLRSTLIIENIPYLRALSD 311

  Fly   273 LMTAVPSQVVANYLTARFSFYIMFTFMK--------HGDSCVTTMRQSMEFASNLLFEERILGRK 329
            ||.:.....|.:|:..::     ..|:|        .|: ||..:|::|..||:.|..::....:
  Fly   312 LMESESPDTVCSYIMLKW-----LAFLKQQGPADISRGE-CVAALRRAMPLASSWLVGQQFSDPE 370

  Fly   330 KLRSYQNQAGKIFDAIRQQLNIRLERNVLKLPPAEISLLQKKLNGLSLSIGNLPGKAGHRRFVTR 394
            .    ::....:|..::.:....|..|.::|.|..:.:||:||..:.|.:|
  Fly   371 S----ESYVSSLFQRLKVRFGQILAENRMRLSPPLVHILQQKLRAVRLQMG-------------- 417

  Fly   395 YYKELEFADDEEL-----ATAH------LKVLEHRTRA--ELSLLDQPNF-----KDRRYMLHSY 441
            :::..|..|.|:.     .:.|      |.:|..|..|  :|..::..||     .:..|:..|:
  Fly   418 FFQTEEIEDVEQYHVRIDLSGHSFYGNQLVLLRQRVEANHDLLYINVTNFANSTGSNLSYLSESW 482

  Fly   442 PISNFFFETAYEENGNTIYVAYDFLADASFDPDSHDIFKVTPLGIRFGLEMLKSFDLFNCKHHKV 506
            ..||  ....|....|.:.|.:..|....:..:...:.:...:|.....|:...||:....:..:
  Fly   483 EASN--SSPLYVRPRNLVLVPHGLLQLPIWHRNISALQQHAVMGFVLAHELAHGFDMLGMDYDAM 545

  Fly   507 -NMLQLFDD---NQITTAGDECV-------SAWTQDNLLSQRDQYLVVLHLVHEAYFAEGSKFSQ 560
             |::...::   ::....|.:|:       |.|..:.|..     .|.|.|.:|.:|....|...
  Fly   546 GNIMGPVEEIGASRQFRQGLQCLQQQMATGSKWIDEKLAD-----FVALRLAYETFFGVRDKREP 605

  Fly   561 RQPNFTTMSLRELFFFRFGQSSFGQT------------LYFGSDFVEGGSPINSLTRLPVFVRTF 613
            |.|.....|.|:|||..|.|...|:|            |...:|.:.   .:.:|.....|.|.|
  Fly   606 RDPLLPQFSQRQLFFITFAQFFCGRTPVLSPRSQSEAHLKHAADELR---VMQTLANFEEFSREF 667

  Fly   614 NC 615
            .|
  Fly   668 GC 669

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl3	NP_608904.1	GluZincin	42..581	CDD:301352	131/625 (21%)
Nepl5	NP_609022.1	PepO	42..684	CDD:226118	144/679 (21%)
		GluZincin	48..682	CDD:301352	141/673 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45454862
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006719
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.740