Protein Alignment Nepl3 and Nep3

DIOPT Version :9

• Sequence 1: NP_608904.1
• Gene: Nepl3 / 326172
• FlyBaseID: FBgn0031678
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_001245775.1
• Gene: Nep3 / 33005
• FlyBaseID: FBgn0031081
• Length: 786
• Species: Drosophila melanogaster
• Alignment Length: 729
• Identity: 149/729 - (20%)
• Similarity: 253/729 - (34%)
• Gaps: 190/729 - (26%)

  Fly    29 EIMKRMLDDMDEKVEPCHNFYNSS-----------QKNLKWHAFATVSDQFQLLFDGIENEVFEK 82
            ||:|    .:|..|:||.:||..|           :....|..|..:....||:   |.| |.||
  Fly   114 EILK----SIDVTVDPCDDFYGYSCNQWIKNNPIPEGKSTWGTFGKLEQMNQLI---IRN-VLEK 170

  Fly    83 --HSFEEKLQRLYKICSTMERPSLLRYFEL------------VKPGEDLNWPFLTPRGGKWPKEK 133
              .||:...:|..|:           |:|.            .||..||    |...|| |...|
  Fly   171 PAKSFKSDAERKAKV-----------YYESCLDADEHMEKLGAKPMNDL----LLQIGG-WNVTK 219

  Fly   134 -----FQWM--EALARL-RRYGFNDIMFGMSIRQDPNSDSGQPIVV------------FEKKYDS 178
                 ..|.  ..|..| .:|.|| .:||.:|.:|..:.|...|.:            :..|.|:
  Fly   220 SGYNVANWTMGHTLKILHNKYNFN-CLFGWAIGEDDKNSSRHVIQIDQGGLTLPTADYYNNKTDN 283

  Fly   179 ----LFRFIESL----------------QNIGL---PPKLAKEIAPLDNAIQE--MYKSDMKFEH 218
                |..:||.:                |.||:   ..|||....||::...|  ||.
  Fly   284 HRKVLNEYIEYMTKVCVLLGANESDARAQMIGVINFEKKLANITIPLEDRRNEEAMYH------- 341

  Fly   219 YARDAAPVKRISLGQLEIYGVSLTKYLE---IVFGRPFSPDFVVHVENLYYLRGLQNLM-----T 275
                  |::...|.:|..: ::.|.:.:   .:.||..:.|.||.|....:|:.|.:::     |
  Fly   342 ------PMQLRQLSKLAPF-LNWTDHFDNAMQMVGRRVTDDEVVVVYAPDFLKNLSDIILKMEQT 399

  Fly   276 AVPSQVVANYLT--------------ARFSFYIMFTFMKHGDS-------CVTTMRQSMEFASNL 319
            ......:.|||.              .|.::..:...:...|.       ||:.....:.||...
  Fly   400 EEGKITLNNYLVWQAVRTLTSCLSKPFRDAYKGVRKALMGSDGGEEIWRYCVSDTNNVVGFAVGA 464

  Fly   320 LFEERILGRKKLRSYQNQAGKIFDAIRQQLNIRLERNVLKLPPAEISLLQKKLNGLSLSIGNLPG 384
            :|..:....:...:.:....:|.:|.:..|     :|:..:.........:|.|.:|..|| .|.
  Fly   465 IFVRQAFHGESKPAAEQMIAEIREAFKMNL-----QNLTWVDKQTREKAIEKANQISDMIG-FPD 523

  Fly   385 KAGHRRFVTRYYKELEFADDEELATAHLKVLEHRTRAELSLLDQP----NFKDRRYMLHSYPISN 445
            .......:.:.|.||....:..... :::|..:..::.|..||||    |:......:::|
  Fly   524 YILDPVELDKKYAELNITPNAYFEN-NIQVAIYNLKSNLKRLDQPVNKTNWGMTPQTVNAY---- 583

  Fly   446 FFFETAYEENGNTIYVAYDFLADASFDPDSHDIFKVTPLGIRFGLEMLKSFDLFNCKHHKV-NML 509
                  |....|.|......|....||.::........:|:..|.|:..:||....::.|. |:.
  Fly   584 ------YTPTKNQIVFPAGILQTPFFDINNPKSLNFGAMGVVMGHELTHAFDDQGREYDKFGNIN 642

  Fly   510 QLFDDNQITTAGD--ECVSAWTQDNLLSQR--------DQYLVVLHLVHEAYFAEGSKFSQRQPN 564
            :.:|...|....:  ||::.......::.|        .:.:.....:..||.|.....|.|..:
  Fly   643 RWWDSKSIERFNEKSECIARQYSGYKMNGRTLNGKQTLGENIADNGGLKAAYHAYQRTKSDRDVD 707

  Fly   565 F-----TTMSLRELFFFRFGQ----SSFGQT--LYFGSDFVEGGSP-----INSLTRLPVFVRTF 613
            .     ..::..:|||..|.|    |:..:|  |....|   ..||     |.:|:.:..|...|
  Fly   708 ILKLPGLNLTHSQLFFVSFAQVWCSSTTDETNLLQMEKD---PHSPSQFRVIGTLSNMKEFAEVF 769

  Fly   614 NCLAPGEQLTTTQK 627
            .| .||:::..|:|
  Fly   770 QC-KPGKRMNPTEK 782

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl3	NP_608904.1	GluZincin	42..581	CDD:301352	130/661 (20%)
Nep3	NP_001245775.1	M13	123..784	CDD:189000	145/716 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45454985
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740