Protein Alignment Nepl3 and goe

DIOPT Version :9

• Sequence 1: NP_608904.1
• Gene: Nepl3 / 326172
• FlyBaseID: FBgn0031678
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_001285350.1
• Gene: goe / 32660
• FlyBaseID: FBgn0027528
• Length: 879
• Species: Drosophila melanogaster
• Alignment Length: 752
• Identity: 135/752 - (17%)
• Similarity: 245/752 - (32%)
• Gaps: 232/752 - (30%)

  Fly     8 LSLSWLLLLLC----------STVCSANPNLEIMKRMLDDMDEKVEPCHNFYNSSQKNL------ 56
            |.|..::|||.          :.:|.....:|..:::|...:....|||..|..:..|.
  Fly   139 LLLLIIILLLAFWPEVPFYLRAPLCLDKECVESSRQLLLWANTSKSPCHETYEWACGNFASDYAN 203

  Fly    57 ---------KWHAFATVSDQFQLLFDGIENEV---------FEKHSFEEKLQRLYKICSTMERPS 103
                     :|: :.|.::..:|      ||:         .::.|.|..:..||:.|...:
  Fly   204 HEYFVIKRGEWN-YETYNEYQEL------NELNRFIAMLPNSQEGSVESTVSSLYRSCRETD--- 258

  Fly   104 LLRYFELVKPGEDLNWPFLTPRGGKWPKEKFQWMEALARLRRYGFNDIMFGMSIRQDPNS----D 164
                 .|.|...||                         |.:...|.: :|....:|.|.    :
  Fly   259 -----VLDKSQSDL-------------------------LLKRAINAV-YGWQAFRDSNRLQSWE 292

  Fly   165 SGQPIVVFEKKYDSLFRFIESLQN----------------IGLPPK-----------------LA 196
            ..:.:||.:.|:.....:..:::|                :|||.|                 |.
  Fly   293 YKRVLVVLQAKHGIFPYYRVTVENGFSNPHDYVITLDEGELGLPDKYFYGNDADEEVVRGYKLLL 357

  Fly   197 KEIA--------PLDNAIQEMYKSDMKFEHYARDA-----APV-KRISLGQLEIYGVSL--TKYL 245
            ::.|        ..|....:::..:.:..::..||     .|: |.:.|..|:|...||  .:.|
  Fly   358 RDFAINMGIVSREADLFADDIFHYERRIVNHIEDAKADANRPINKLMRLADLKIKAPSLPILESL 422

  Fly   246 EIVFGR-PFSPDFVVHVENLYYLRGLQNLMTAVPSQVVANYLTARFSFYIM-------------F 296
            :.:|.: ..:.|..|.|.:...:..|..|::....:.:.|::....:..::             |
  Fly   423 QAIFPKTKITEDTEVLVRDPEVMHALSVLLSTSDKKPINNFIVWSLARKMLPHLSKEYRTLAETF 487

  Fly   297 TFMKHGDS--------CVTTMRQSMEFASNLL--------FE---ERILGRKKLRSYQNQAGKIF 342
            ....:|.:        |...:|..:.||.:.|        ||   .:..|..|.:..:.....:|
  Fly   488 DHALYGRTASYPRWLICSKVVRDWLPFAVDALQQQPPRQQFETMTSKSRGLNKTQGNEELLKLMF 552

  Fly   343 DAIRQQLNIRLERNVLKLPPAEISLLQKKLNGLSLSIGNLPGKAGHR-RFVTRYYKEL-----EF 401
            .::|.||...||: ...|.||....:|||||.:.|..| :|.:...: .::.:||.||     .|
  Fly   553 FSLRNQLKDSLEQ-AKWLEPAARQFIQKKLNEMRLQFG-IPDEVLQQPTYLAQYYNELILNNVFF 615

  Fly   402 ADDEE----------------LATAHLKVLEHRTRAELSLLDQPNFKDRRYMLHSYPISNFFFET 450
            .:..|                ||...:.|.|..||.....:...| |....::....||:.:::.
  Fly   616 VEHLEWIWTFRRSQMEKKLGPLAILDVIVSEMYTRDNPQAIAYSN-KLNMLLVSKVLISSNYYDY 679

  Fly   451 AYEENGNTIYVAYDFLAD---------ASFDPDSHDIFKVTPLGIRFGLEMLKSFDLFNCKH--- 503
            .|....|...:..|.|..         ..|:..|.||....| .||:....:      ||..
  Fly   680 RYPVAVNFARIGTDILEALIDNFSTFLLQFNTQSTDISDAAP-EIRYAQPDV------NCLAAGQ 737

  Fly   504 -----HKVNMLQLFDDNQITTAGDECVSAWTQDNLLSQRDQYLVVLHLVHEAYFAEGSKFSQ--- 560
                 |::|.|   ..|.:.:......:|.|....||.      .::.:......:||...|
  Fly   738 PPRLVHELNEL---SSNALKSFHVTLSAARTAARALSN------FVNAIDAGSAIQGSGIDQANT 793

  Fly   561 ----------RQPNFTTMSLRELFFFRFGQSSFGQTL 587
                      |.|...:.:..|||...:.|.....|:
  Fly   794 YEALGLTRRLRIPGLRSFNENELFTLSYMQQHCSTTI 830

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl3	NP_608904.1	GluZincin	42..581	CDD:301352	125/700 (18%)
goe	NP_001285350.1	GluZincin	184..>694	CDD:301352	98/553 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45454866
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740