Protein Alignment Nepl3 and Nep6

DIOPT Version :9

• Sequence 1: NP_608904.1
• Gene: Nepl3 / 326172
• FlyBaseID: FBgn0031678
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_001245645.1
• Gene: Nep6 / 32234
• FlyBaseID: FBgn0030425
• Length: 655
• Species: Drosophila melanogaster
• Alignment Length: 740
• Identity: 145/740 - (19%)
• Similarity: 260/740 - (35%)
• Gaps: 229/740 - (30%)

  Fly     9 SLSWLLLLLCSTVCSANPNLEIMKRMLDDMDEKVEPCHNFY---------NSSQKNL-------K 57
            |::.|:::|...:.......:..:::.:|.|.:|:||.||:         |:||:.|       |
  Fly     7 SITRLVVILGVMLLKLAAAQDCQQQLDNDTDAEVKPCENFHQYACGNWYSNTSQRILGAHDMRSK 71

  Fly    58 WHAFATVSDQFQL---LFDGIENEVFEKH----SFEEKLQRLYKICSTMERPSLLRYFE-LVKPG 114
            |.|    :.:.||   |.:....:.|..:    :...:|..||: |..:...|:..|.: |.:.|
  Fly    72 WVA----NLKLQLIRYLEESSSTDSFSANTSVTTSTAQLGTLYR-CCLLSGQSIRTYTDALSRSG 131

  Fly   115 EDLNWPFLTPRGGKWPKEKFQWMEALARLRRYGFNDIMFGMSIRQDPNSDSGQPIVVFEKKYDSL 179
              .|:|.|....|    ..|.|:.|.|.||.||... ::.:.::.:..|...:...:...|:|.|
  Fly   132 --ANFPLLANHTG----GSFDWVLANAALRTYGAQG-LWRLLVKDNWQSADQRIFYMLPPKFDLL 189

  Fly   180 FRFIE------------SLQNIGLPPK----LAKEIAPLDNAIQEMYKSDMKFEHYARDAAPVKR 228
            .|..|            .|..:||..:    ||:::...:.::|::..:|.:.....|....:|.
  Fly   190 GRDDELNEFLYQRYLKILLLELGLRVRRAALLAEKLVAFEKSLQKLLPNDAEQTLVLRKPQSLKD 254

  Fly   229 I--SLGQLEIYGVSLTKYLE-IVFGRPFSPDFVVHVENLYYLRGLQNLM---TAVPSQVVANYLT 287
            :  .|.:||     |.:|.| |:.|..:....::.|.:|.||:|||.|:   |:.| .|::.:|.
  Fly   255 LESQLPRLE-----LKRYFETILEGIDWDSKTLLLVADLDYLQGLQRLLAEHTSDP-MVLSTWLL 313

  Fly   288 ARFSFYIMFTFMKHGDS--------CVTTMRQSMEFASNLLFEERILGRKKLRSYQN-------Q 337
            .:...|  |....|.|.        |:..:|:.|......|..:.:||    .|||:       |
  Fly   314 LQLPAY--FELRLHDDDKLGNQRNHCLEQLRKLMPGQLGRLQMQLVLG----ESYQDVYDTAIQQ 372

  Fly   338 AGKIFDAIRQQLNI---------------RLERNVLKLPPAEISLLQKKLNG------------- 374
            ...:|..::||..:               .|.|:.|:........||..:||
  Fly   373 IAVLFRDLKQQFELVLNETEVFNEDLVTRNLARDKLRAMRLLTPRLQDPINGGPGTPQLGGNCDA 437

  Fly   375 ----LSLSIGNLPGKAGHRRFVTRYYKELEFAD-------DEELATAHLKVLEHRTRAELSLLDQ 428
                ||||...|.            |::: |.:       |.....|:.::..:|....|.|:..
  Fly   438 NLLQLSLSQAKLE------------YRQV-FGEPVTSVPADPLSVNAYYRLKLNRIELPLGLMAT 489

  Fly   429 PNFKDR--------------------RYMLHSYPISNFFFETAYEENGNTIYVAYDFLADASFDP 473
            |..:.:                    ..|:|::.:...    .|:..|.        ||:..:..
  Fly   490 PLIQQQCSKEADTRAKLSAGLGYILAHEMVHAFDLDGL----NYDATGQ--------LANGQWSA 542

  Fly   474 DSHDIFKVTPLGIRFGLEMLKSFDLFNCKHHKVNMLQLFDDNQITTAGDECVSAWTQDNLLSQRD 538
            .:     :...|:|.|..:...:.         |.....::|...|.|
  Fly   543 RA-----IIRFGLRAGCYLGVRYS---------NATLTVNENIADTEG----------------- 576

  Fly   539 QYLVVLHLVHEAYFAEGSKFSQRQPNFTTMSLRELFFFRFGQ-------SSFGQTLYFGSDFVEG 596
                 |.|..:.|     :......|..|      ||..|.|       |:.|.:.:.|.
  Fly   577 -----LRLALDTY-----RHRSGATNLRT------FFVAFAQNWCGTVASTSGLSQHAGH----- 620

  Fly   597 GSPINSLT-RLPVFVRTFNCLAPGE 620
            ...:|::. .:|.|..||.|.|..:
  Fly   621 AERVNNVVGNMPEFGDTFECKATSQ 645

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl3	NP_608904.1	GluZincin	42..581	CDD:301352	130/665 (20%)
Nep6	NP_001245645.1	PepO	35..655	CDD:226118	142/712 (20%)
		M13	40..653	CDD:189000	140/707 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45454870
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006719
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.740