Protein Alignment Nepl3 and nep-25

DIOPT Version :9

• Sequence 1: NP_608904.1
• Gene: Nepl3 / 326172
• FlyBaseID: FBgn0031678
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_495164.2
• Gene: nep-25 / 191543
• WormBaseID: WBGene00022874
• Length: 515
• Species: Caenorhabditis elegans
• Alignment Length: 714
• Identity: 116/714 - (16%)
• Similarity: 215/714 - (30%)
• Gaps: 330/714 - (46%)

  Fly    13 LLLLLCSTVCSANPNLEIMKRMLDDMDEKVEPCHNFYNSSQKNLKWHAFATVSDQFQLLFDGIEN 77
            :.:|.|::..|...|: |.:.:....|..|:||.:||
 Worm    12 VFILFCTSKASLPKNI-IQEHIKKHADFSVDPCVDFY---------------------------- 47

  Fly    78 EVFEKHSFEEKLQRLYKICSTMERPSLLRYFELVKPGEDLNWPFLTPRGGKWPKEKFQWMEALAR 142
                .|           :|                               .|..|:: :||.|::
 Worm    48 ----AH-----------VC-------------------------------PWKVERY-FMEDLSK 65

  Fly   143 LRRYGFNDIMFGMSIRQDPNSDSGQPIVVFEKKY--------DSLFRFIESLQNIGL-------- 191
            |:.        ||             :..:.||:        :..|...|:|:.:.:
 Worm    66 LKA--------GM-------------VAKYRKKHPKFDKFKGEDAFAIAEALKQLNIEQLKSECK 109

  Fly   192 --PPKL------AKEIAPLDNAIQEMYKSDMKFEHY-ARDAAPVKRISLGQLEIYGVSLTKYLEI 247
              .|:|      |::...::|..:.::..   ||:| ..:.|.:....:|::|.|..:.:..:..
 Worm   110 PSKPRLSSFFISAQDNRTIENVDEVLFPG---FENYPCEEKAAIIIKEVGEIEDYTTTRSVLVSA 171

  Fly   248 VFGRPFSPDFVVH--VENL-YYLRGLQNLMTAVPSQVV------ANYLTARFSFYIMFTFMKHGD 303
            |.|      |:..  ||.| ...|.|.|...:|.|:.:      .||
 Worm   172 VNG------FITSKLVEKLDVKARKLFNKFKSVISKEIIKTPWAKNY------------------ 212

  Fly   304 SCVTTMRQSMEFASNLLF----EERILGRKKLRSYQNQAGKIFDAIRQQLNIRLERNVLKLPPAE 364
               ..:.|.:|..||:.|    :.||..:|.:..|::                .|::
 Worm   213 ---KAIEQYVEALSNITFRTFADVRITVKKSMELYES----------------TEKD-------- 250

  Fly   365 ISLLQKKLNGLSLSIGNLPGKAGHRRFVTRYYKELEFADDEELATAHLKVLEHRTRAELSLLDQP 429
               .:|||                         ::.|:.    .||.|......||....|||:|
 Worm   251 ---CRKKL-------------------------DVAFSQ----PTAELVCKGVATRKAEELLDEP 283

  Fly   430 -----------NFKDRRYMLHSYPISNFFFETAYEENGNTIYVAYDFLADASFDPDSHDIFKVTP 483
                       ..||...|.:|:              .|::|:..:||...:.|..| |::.
 Worm   284 IEDIFPQDQAGILKDVWQMFNSF--------------DNSVYIGNEFLLLLNTDYFS-DLYG--- 330

  Fly   484 LGIRFGLEMLKSFDLFNCKHHKVNMLQLFDDN-------QITTAGDECVSAWTQDNLLSQRDQYL 541
               ..|..|:          |::....:||||       ::.|...:||    :|..|...:.:.
 Worm   331 ---SIGFSMI----------HEIMHTLVFDDNDLDKPLSKLWTKNADCV----KDQALKTCETFP 378

  Fly   542 VVLHL----------------------------VHEAYFAEGSKFSQRQPNFTTMSLRELFFFRF 578
            .|..:                            ::|..:|..:..    ||:..:..::|||
 Worm   379 TVTEMHNMKPACNTTVTFEEDAADLAAYRIAWRIYENSYARKTVV----PNYEALDKKQLFF--- 436

  Fly   579 GQSSFGQTLYFGSDFVEGGS--------------PINSL-TRLPVFVRTFNCLAPGEQLTTTQK 627
                :|..::|.:.  :|.|              .:||| :::..|...|.|....:.:|...|
 Worm   437 ----YGAAVFFCNQ--DGMSRVPFQNLAHSNNYQRVNSLMSQMKQFSDAFKCKPTDKMITNRAK 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl3	NP_608904.1	GluZincin	42..581	CDD:301352	98/622 (16%)
nep-25	NP_495164.2	Peptidase_M13	308..496	CDD:279739	39/221 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900