Protein Alignment Nepl3 and nep-24

DIOPT Version :9

• Sequence 1: NP_608904.1
• Gene: Nepl3 / 326172
• FlyBaseID: FBgn0031678
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_503005.3
• Gene: nep-24 / 190993
• WormBaseID: WBGene00013786
• Length: 567
• Species: Caenorhabditis elegans
• Alignment Length: 562
• Identity: 114/562 - (20%)
• Similarity: 190/562 - (33%)
• Gaps: 173/562 - (30%)

  Fly    13 LLLLLCS-------------TVCSANPNLEIMKRMLDDMDEKVEPCHNFYNSSQKNLKWHAFATV 64
            ||||.|:             .||:....:.:...:.:..|..|:||.||:..:......|....:
 Worm    16 LLLLTCTAPLAIGATTPATRNVCNTPACITLAHMLHNYHDPSVDPCDNFHQFACGREHEHETEDI 80

  Fly    65 SDQFQLLFDGI------ENEVFEKHSFEEKLQRLYKICSTMERPSLL-RYFELVKPGEDLN---- 118
            ..:.....:.|      :||.....| |..::.|||.|.|:|:.|.. |...|....:|:.
 Worm    81 YTKKTKTINNIMKRFLKKNETSRSKS-ENAMRTLYKACKTLEKNSTASRNKALQDIFQDIQSIGA 144

  Fly   119 WPFLTPRGGKWPKEKFQWMEALARLRRYGFNDIMFGMSIRQDPNSDSGQPIVVFEKKYDSLFRFI 183
            ||.:   ..||.:.||...:.|..|.|.|..:  ||:                |:     :.|::
 Worm   145 WPVV---DDKWDESKFDLNDFLVNLVRLGRKN--FGL----------------FQ-----MARYV 183

  Fly   184 ESLQNIGLPPKLA-KEIAPLDNAIQEMYKSDMKFEHYARDAAPVKRISLGQLEIYGVSLTKYL-- 245
             :::|..:.|:.| :....|...|.|:.|        |.......:..|..|..| |:|.|.|
 Worm   184 -NVRNFAIGPEAAWRHNVDLGKTISEILK--------ANSVQTNNKKLLDDLAEY-VNLEKALSQ 238

  Fly   246 --------------------EIVFGR----PFSPD---FVVHVENLYYL----------RGLQNL 273
                                .:.|.|    ..|||   ....|..:.||          ..|:.:
 Worm   239 HKFNTVQPGYIFSERSDFVSSVNFSRLVLEMMSPDKRTLFPEVYQIMYLTNTSLFFGKNNNLETI 303

  Fly   274 MTAVPSQVVANYLTARFSFYIMFTFMKHGDSCVTTMRQSMEFASNLLF-EERI---LGRKKLRS- 333
            :.....:.:||||..:|               :.|....:.:.|...| |:::   |.|..||:
 Worm   304 IRNTSKRALANYLIFKF---------------IDTSIADLTYGSPSAFCEQKVINFLPRAALRAF 353

  Fly   334 YQN--------QAGKIFDAIRQQLNIRLERNVLKLPPAE--ISLLQKKL-----NGLSLSIG--- 380
            |:|        :..|:.:|.:.||        ||:..|.  :|:..||:     :.:::.||
 Worm   354 YRNFISKENRKKITKLTEATQVQL--------LKIIGATDWMSIKSKKIAMDRVSSMNMVIGYPD 410

  Fly   381 --NLPGKAGHRRFVTRYYKELEFADDEELATAHLKVLEHRTRAELSLLDQPNFKDRRYMLHSYPI 443
              :.|||      :...::.|..:..:...|...|:.......|:.           |.....|.
 Worm   411 YFDPPGK------LDGLFEHLNLSSSDTYYTVVRKINRFMREQEMD-----------YYTGEVPY 458

  Fly   444 SNFF----FETAYEENGNTIYVAYDFLADASFD---PDSHDI 478
            ...|    ....|..|.|.:.:...|..|..||   ||..:|
 Worm   459 YPLFPGLMTNAMYNANDNNLMIFAPFFDDPFFDSSFPDYANI 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl3	NP_608904.1	GluZincin	42..581	CDD:301352	106/520 (20%)
nep-24	NP_503005.3	GluZincin	58..561	CDD:301352	106/520 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161783
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740