Protein Alignment Nepl3 and nep-20

DIOPT Version :9

• Sequence 1: NP_608904.1
• Gene: Nepl3 / 326172
• FlyBaseID: FBgn0031678
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_001317749.1
• Gene: nep-20 / 188176
• WormBaseID: WBGene00020293
• Length: 834
• Species: Caenorhabditis elegans
• Alignment Length: 727
• Identity: 142/727 - (19%)
• Similarity: 264/727 - (36%)
• Gaps: 198/727 - (27%)

  Fly    10 LSWLLLLLCS------TVCSANPNLEIMKRMLDDMDEKVEPCHNFYNSSQKNLKWHAFATVSDQF 68
            |.||||.:.:      ::|.:...:.:...:....|..|..|||||.::....|.|   ...|:.
 Worm   197 LFWLLLFIGARQDEKPSLCESPQCITLAFELSAYQDTSVSKCHNFYKATCGKYKHH---QALDKH 258

  Fly    69 QLLFDGIENEVFEK--------------HSFEEKLQRLYKICSTMERPSLLRYFELVKPGEDLNW 119
            :   |..:.||.::              ..||..::.::..|:...:..  .|.::.|..|.:
 Worm   259 R---DAKKKEVVKRIVREFLRRNESSITSKFEPAIRLMFGKCNKFSQNK--TYLDIFKDIEKI-- 316

  Fly   120 PFLTPRGGKWPKEKFQWMEALARLRRY-------GFNDI-MFGMSIRQDPNSDSGQ-PIVV--FE 173
                   |.||..|..|::.:..|..|       ||.|. :|.:..||   ...|| |::.  .:
 Worm   317 -------GPWPVLKSDWVDVMFNLNDYLLSLVELGFTDFGLFKLEFRQ---LAFGQFPVIAPSEQ 371

  Fly   174 KKYDSLFRFI-ESLQNIGLPPKLAKEIAPLDNAIQEMYKSDMKFEHYARDAAPVKRISLGQLEIY 237
            |:.:.|.:.| |.|:..|:.....|    |...::|..:...:..|.:.:...||.|......:
 Worm   372 KQGNQLEKIILEILEANGVQADRQK----LSKYLREYSEFKSQLRHMSLEGTSVKYIRYNASTL- 431

  Fly   238 GVSLTKYLEIVFGRPFSPDFVVHVE--------NLYYLRGLQNLMTAVPSQVVANYLTARFSFYI 294
            .|:::..::.:.....|...|..::        :.::.:.|..::.....:.:||||.  |.|..
 Worm   432 SVNISALVQKMAPMSTSSGLVRRIQSGILITNSSSFFGKNLDAIIQQTHKRTLANYLI--FHFID 494

  Fly   295 MFTF-----MKHGDSCVTTM--RQSMEFASNLLFEERILGRKKLRSYQNQAGKIFDAIRQQLNIR 352
            ..||     .||.:..:..:  |.|::..|....:|...|                 :..::...
 Worm   495 AVTFDLTSGAKHSEHTLIDLLPRGSLQVLSQDFVDEEDQG-----------------VMVEMAKD 542

  Fly   353 LERNVLKLPPAEISLLQKKLNGLSLSIGNLPGKAGHRR----------FVTRYYKELEFADDEEL 407
            |:::|:::    ||      .|.||..|:|..:...||          .||:|..|:...:.|:|
 Worm   543 LKKHVVEM----IS------EGSSLDKGHLVFEEKERRKLIRKVQDILVVTKYPLEILNQNFEKL 597

  Fly   408 ATAHL----KVLE--HRTRAELSLLD------QPNFKDRRYMLHSYPISNFFFETAYEENGNTIY 460
            ...:.    |:::  .|.|:| .|::      .|..|......|            ||:..|.:.
 Worm   598 NLTYSDSLHKIIQKLRRFRSE-QLIEYLGGDLDPTDKGMWGSAH------------YEQATNDLI 649

  Fly   461 VAYDFLADASFDPDSHDIFKVTPLGIRFGLEMLKSFDLFNC----KHH-----KVNMLQLFDDNQ 516
            :....:....||....:...:..:|.....|:.:|.|....    |.|     |...|:.||:|
 Worm   650 IIAPIIDGPYFDTSYPNYVNIFFMGFIISRELGRSLDSVRIRKDEKGHTENWLKSESLKRFDNN- 713

  Fly   517 ITTAGDECVSAW----TQDNLLSQRDQYLVVLHLVHEAYFAEGSKFSQRQPN---------FTTM 568
                    |..|    |....|::    ::..|:.|||.|....|: :::.|         :.:|
 Worm   714 --------VKCWRKKITGTRFLNE----MLADHVGHEASFMALKKW-EKEMNGTIVEKIRGYESM 765

  Fly   569 SLRELFFFRFGQSSFGQTLYFGSDFVEGGSP---------------IN-SLTRLPVFVRTFNCLA 617
            ::.::||..       |.|||...  .|||.               :| :...:|.|.:.|.| :
 Worm   766 TMEQIFFHL-------QALYFCRP--PGGSTGELTAKDARQHYSTRVNEAFKNMPQFAKAFGC-S 820

  Fly   618 PGEQLTTTQKST 629
            ..:.:.:..|.|
 Worm   821 SNQNMNSKTKCT 832

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl3	NP_608904.1	GluZincin	42..581	CDD:301352	121/623 (19%)
nep-20	NP_001317749.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161781
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740