Protein Alignment Nepl3 and Phex

DIOPT Version :9

• Sequence 1: NP_608904.1
• Gene: Nepl3 / 326172
• FlyBaseID: FBgn0031678
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_035207.1
• Gene: Phex / 18675
• MGIID: 107489
• Length: 749
• Species: Mus musculus
• Alignment Length: 582
• Identity: 102/582 - (17%)
• Similarity: 197/582 - (33%)
• Gaps: 197/582 - (33%)

  Fly     8 LSLSWLLLLLCSTV---------CSANPNLEIMKRMLDDMDEKVEPCHNFY----------NSSQ 53
            |.|..||.|:...:         |.....:|....::..::..|:||.||:          |...
Mouse    31 LVLGTLLFLVSQGLLSFQAKQEYCLKPECIEAAAAIMSKVNLSVDPCENFFRFACDGWISNNPIP 95

  Fly    54 KNL-KWHAFATVSDQFQLLFDG-IENEVFEKHSFE--EKLQRLYKIC---STMERPS------LL 105
            ::: .:..:..:.....|.... :|..|..:...|  :|.:.||..|   ..:|:..      :|
Mouse    96 EDMPSYGVYPWLRHNVDLKLKALLEKSVSRRRDTEAVQKAKILYSSCMNEKAIEKADAKPLLHIL 160

  Fly   106 RYFELVKPGEDLNWPFLTPR---GGKWPKEKFQWMEALARLRRYGFNDIMFGMSIRQDPNSDSGQ 167
            |:       ....||.|...   .|.|.:.||..::.||..|....|.:...:.:..|..: |.:
Mouse   161 RH-------SPFRWPVLEANIGPEGVWSERKFSLLQTLATFRGQYSNSVFIRLYVSPDDKA-SNE 217

  Fly   168 PIVVFE-------------------KKY-DSLFRF-IESLQNIG---------------LPPKLA 196
            .|:..:                   |.| |:|::| :::...:|               |..|:|
Mouse   218 HILKLDQATLSLAVREDFLDNTTEAKSYRDALYKFMVDTAVLLGANSSRAEHDMKSVLRLEIKIA 282

  Fly   197 KEIAPLDNAIQEMYKSDMKFEHYARDAAPVKRIS-LGQL-EIYGVSLTKYLEIVFGRPFSPDFVV 259
            :.:.|.:|...|...:.|.....   :|.:.:.. ||.: ::....|..:|:.:  .| |.:.||
Mouse   283 EIMIPHENRTSEAMYNKMNISEL---SAMIPQFDWLGYIKKVIDTRLYPHLKDI--GP-SENVVV 341

  Fly   260 HVENLYYLRGLQNLMTAVPSQVVANY------------LTARFSF-YIMF--------TFMKHGD 303
            .|..  |.:.|..::.|...:.:|||            |:.||.: ::.|        |.:...|
Mouse   342 RVPQ--YFKDLFRILGAERKKTIANYLVWRMVYSRIPNLSRRFQYRWLEFSRVIQGTTTLLPQWD 404

  Fly   304 SCVTTMRQSMEFASNLLFEERILGRKKLRSYQNQAGKIFDAIRQQLNIRLERNVLKLPPAEISLL 368
            .||..:..::.:.                     .||:|      :|:..:.:       :..::
Mouse   405 KCVNFIESALPYV---------------------VGKMF------VNVHFQED-------KKEMM 435

  Fly   369 QKKLNGLSLSIGNLPGKAGHRRFVTRYYKELEFADDEELATAHLKVLEHRTRAELSLLDQPNF-- 431
            ::.:.|:..:            |:....||.|:.|    |....|..| :.||.|:.:..|.|
Mouse   436 EELIEGVRWA------------FIDMLEKENEWMD----AGTKRKAQE-KARAVLAKVGYPEFIM 483

  Fly   432 ------------------------KDRRYMLHSYPISNFFF------ETAYEENGNTIYVAY 463
                                    :.|:|:..    |:||:      :|.:..|..|:...|
Mouse   484 NDTYVNEDLKAIKFSESDYFGNVLQTRKYLAQ----SDFFWLRKAVPKTEWFTNPTTVNAFY 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl3	NP_608904.1	GluZincin	42..581	CDD:301352	95/539 (18%)
Phex	NP_035207.1	PepO	67..741	CDD:226118	95/546 (17%)
		M13	74..747	CDD:189000	95/539 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810