Protein Alignment Nepl3 and nep-3

DIOPT Version :9

• Sequence 1: NP_608904.1
• Gene: Nepl3 / 326172
• FlyBaseID: FBgn0031678
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_494679.2
• Gene: nep-3 / 173730
• WormBaseID: WBGene00016778
• Length: 634
• Species: Caenorhabditis elegans
• Alignment Length: 723
• Identity: 141/723 - (19%)
• Similarity: 237/723 - (32%)
• Gaps: 252/723 - (34%)

  Fly    13 LLLLL------------CS--TVCSANPN----------LEIMKRMLDDMDEKVEPCHNFYNSSQ 53
            |:|||            ||  :..||:|.          :.::.::|:..|..|:||.|||.::.
 Worm    29 LVLLLEAGKIGGEVSENCSNHSTSSASPKPKPMCLTPECITLVHQLLNFQDPSVDPCENFYQAAC 93

  Fly    54 KNLKWHAFATVSDQFQ-------LLFDGIENEVFEKHSFEEKLQRLYKIC------STMERPSLL 105
            .....|.....|...|       |:.|.:..........|..::.||:.|      ..:...:||
 Worm    94 GKYNEHNVIDGSRTAQKQQIVKRLIRDFLHKNQSSTSKSENSMKLLYEKCKEAKTIKVLGNQNLL 158

  Fly   106 R--YFELVKPGEDLNWPFLTPRGGKWPKEKFQWMEALARLRR-----YGFNDIMFGMSIRQDPNS 163
            :  :..:.|.|   :||.|..   .|..:||...|.|..|.|     :||.:|:.        :|
 Worm   159 QEIFMNIQKIG---SWPVLDE---NWDGKKFNLNEMLLSLIRLGVSNFGFFEIII--------SS 209

  Fly   164 DSGQPIVVFEKKYDSLFRFIESLQNIGLPPKLAKEIAPLDNAIQEMYKSDMKFEHYARDAAPVKR 228
            |:                |:              ||.|..|.......||:
 Worm   210 DA----------------FV--------------EIKPARNFPTRENLSDI-------------- 230

  Fly   229 ISLGQLEIYGVSLTKYLEIVFGRPFSPDFVV------HVENLY-YLRGLQNLMTAVPSQVVANYL 286
            ||               ::..|..|.|:...      ..|||. .|:.|:.|:...|::.:.|||
 Worm   231 IS---------------KVFLGNGFQPNITAIENDLREYENLQRELKSLERLIQTTPNRSLVNYL 280

  Fly   287 TARFSFYIMFTFMK-HGDSCVTTMRQSMEFASNLLFEERILGRKKLRSYQNQAGKIFDAIRQQLN 350
            ...:...:|..:.: ..:.|...:...:..||..:|.:..|. |:.|.|  .||.|.|.....::
 Worm   281 IFNYLKSVMLEYKRLPEEQCEGVVIDFLPRASTRVFVQNFLD-KENRKY--VAGMIEDVKMGFID 342

  Fly   351 IRLERNVLKLPPAEISLLQKKLNGLSLSIGNLPGKAGHRRF------VTRYYKELEFADDEELAT 409
            :..|...|.....::::.:.|         |:....|:..|      :.|.:|:|.....:...|
 Worm   343 MIQESTWLNEESKKVAVQKVK---------NIKSMIGYPDFFEPPGTLDRSFKDLNIEQTDSYHT 398

  Fly   410 AHLKVLEHRTR-------AELSLLDQPNFKDRRYMLHSYPISNFFFETAYEENGNTIYVAYDFLA 467
            ...|:.:....       :|:.|      ..|:.:||:         .|:.:|.|.:.:....|.
 Worm   399 IVRKIQKFTNEQCMEFVASEIPL------DPRQPILHA---------NAFYQNTNFLAILAPVLD 448

  Fly   468 DASFDPDSHDIFKVTPLGIRFGLEMLKSFDLFNCKHHKVNMLQLFDDNQITTAGDECVSAWTQDN 532
            |..||........:..:|.....|:..:||     |..:|    :||     ||.:.:....:|:
 Worm   449 DPIFDTTFPRYVNLAVIGNVLAHEIGHAFD-----HTGIN----YDD-----AGQQRIWLTPEDS 499

  Fly   533 ---------LLSQRDQYLVVLHLVHEAYFA---EGSKFSQRQPNFTTMSLRELFFFRFGQSSFGQ 585
                     ||.|.|:|       .:..|.   .|||           :|.|:...|||..:..:
 Worm   500 EEYGKRLRCLLRQHDEY-------DDPDFGRNLNGSK-----------TLHEISADRFGVEAAWR 546

  Fly   586 T----------------------LYF------------GSDF---VEGGSPINSL------TRLP 607
            |                      |||            .:|.   ::...|.|:.      ..:|
 Worm   547 TFKKLDLSNESEIVGFQNFNIDQLYFRTAALIWCRQRDTTDLQYALQREHPTNNFRVNGIYANMP 611

  Fly   608 VFVRTFNC 615
            .|..||||
 Worm   612 QFAETFNC 619

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl3	NP_608904.1	GluZincin	42..581	CDD:301352	117/591 (20%)
nep-3	NP_494679.2	M13	82..631	CDD:189000	130/670 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161775
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740