Protein Alignment Nepl3 and nep-13

DIOPT Version :9

• Sequence 1: NP_608904.1
• Gene: Nepl3 / 326172
• FlyBaseID: FBgn0031678
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_001342017.1
• Gene: nep-13 / 173672
• WormBaseID: WBGene00018196
• Length: 732
• Species: Caenorhabditis elegans
• Alignment Length: 750
• Identity: 133/750 - (17%)
• Similarity: 246/750 - (32%)
• Gaps: 232/750 - (30%)

  Fly    17 LCST-------VCSANPNLEIMKRMLDDMDEKVEPCHNFYNSSQKNLKWHAFATVSD-------- 66
            :|.|       ||.....:.:...:|:..:..::||.:||..|....:.|   |::|
 Worm    72 ICKTDHNKTRDVCKTAECITLSSTLLNWQNTNIDPCEDFYEYSCGRYQEH---TLNDGIRANEKD 133

  Fly    67 --------QFQLLFDGIENEVFEKHSFEEKLQRLYKICSTMERPSLLRY---------------- 107
                    ||.|     :|:....:| |..|..||:.||       |||
 Worm   134 TIVMKLIRQFVL-----KNQSTTSNS-ENALMLLYEKCS-------LRYRMENRHQETEVIQREV 185

  Fly   108 FELVKPGEDLNWPFLTPRGGKWPKEKFQWMEALARLRRYGFNDIMFGMS--------------IR 158
            ||.::            :.|.||.....|..:     .:..|:::..|:              |.
 Worm   186 FENIR------------KIGSWPIADKNWNSS-----HFNLNNMLSNMASIHMLPFGLFETRVIE 233

  Fly   159 QDPNSDSGQPIVV------FEKKYDSLFRFIESLQNI----GLPPKLAKEIA------------- 200
            ..|.:.:.:.:|:      |....:.|.|.|..|.::    .:..|:.:::|
 Worm   234 LYPMNTTAKQLVIRPTKLKFSIPQEELVRAIRDLLSVNGITSIMKKVKEDVAESFALDKEIGNIH 298

  Fly   201 ----PLDNAIQEMYKS--DMKFEHYARDAAPVKRISLGQLEIYGVSLTKY----LEIVFGRPFSP 255
                |....:.|:.|:  |:.||...:.....|..:...|.      ||.    .|:.||:.
 Worm   299 IDPQPKPATLSELQKAVPDIDFERIIKSYLNPKTGNWSSLR------TKIFSARFELFFGKN--- 354

  Fly   256 DFVVHVENLYYLRGLQNLMTAVPSQVVANYLTARFSFYIMFTFMKH------GDSCVTTMRQSME 314
                        ..|.:::.....:::||||..::..|..|.|..:      .|.|...:..|:.
 Worm   355 ------------NNLSSIIARTKPRILANYLFLKYIEYAYFFFFDNTKVFSDDDFCTEVVTTSLP 407

  Fly   315 FASNLLFEERILGRKKLRSYQNQAGKIFDAIRQQL-----NIRLERNVLKLPPAEISLLQKKLNG 374
            .||..:|......::.:.    .|.:|.:.::...     |.....|..:....|..:..||:.|
 Worm   408 RASLRVFVRNHFKKENMA----VASEIVEVVKTAYVEIINNSTWLHNSTRESAIEKVVKMKKVIG 468

  Fly   375 LSLSIGNLPGKAGHRRFVTRYYKELE--FADDEELATAHLKVLEHRTRAELSLLDQPN-FKDRRY 436
                                |.:|.|  .|.||...|..|.    |:.:...|:.:.| ||..:.
 Worm   469 --------------------YTEEYERTGALDEMFETLQLS----RSDSFFVLMTKVNRFKIEQL 509

  Fly   437 M-----------LHSYPISN-FFFETAYEENGNTIYVAYDFLADASFDPDSHDIFKVTPLGIRFG 489
            |           :....::| |:|.|.     |.:.|...||....||........:..:|....
 Worm   510 MDFVSSDSLLNPIEPLVMANAFYFPTK-----NLLNVLVPFLDKPLFDFKYPRYVAMAGVGRVLA 569

  Fly   490 LEMLKSFDLFNCKHHKVNMLQLF---DDNQITTAGDECVSA----WTQDNLLSQRDQYLVVLHLV 547
            .|:..:||:...:..::...:.:   :|.:......||.:.    :...:...:::...|:..::
 Worm   570 HEIGHAFDINGRQTDEIGRTRDWWTREDTEEYDRRSECFAEQFTNFKDPSFKGKQNGTEVLAEII 634

  Fly   548 HEAYFAEGSKFSQRQPNFTTMSLRELFFFRFGQSSFGQTLYF---GSDFV-----------EGGS 598
            .:|...|.|..:.::.|.|    .|....:|....||: |||   ..||.           :...
 Worm   635 ADALGMEASWIAFKKINLT----EEQGLIQFEDHDFGK-LYFQVAALDFCAPSRIEERYSDQLSH 694

  Fly   599 PIN------SLTRLPVFVRTFNCLAPGEQLTTTQK 627
            |.|      :.:....|..|:.| ..|.::...|:
 Worm   695 PTNKFRINGAFSNSRAFADTYKC-PVGSKMNPVQR 728

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl3	NP_608904.1	GluZincin	42..581	CDD:301352	114/650 (18%)
nep-13	NP_001342017.1	M13	104..729	CDD:189000	128/717 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161777
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740