Protein Alignment eIF2alpha and eif-2alpha

DIOPT Version :10

• Sequence 1: NP_573130.1
• Gene: eIF2alpha / 32617
• FlyBaseID: FBgn0261609
• Length: 341
• Species: Drosophila melanogaster
• Sequence 2: NP_001368001.1
• Gene: eif-2alpha / 171769
• WormBaseID: WBGene00021351
• Length: 342
• Species: Caenorhabditis elegans
• Alignment Length: 344
• Identity: 170/344 - (49%)
• Similarity: 238/344 - (69%)
• Gaps: 13/344 - (3%)

  Fly     6 RFYNERYPEIEDVVMVNVLSIAEMGAYVHLLEYNNIEGMILLSELSRRRIRSINKLIRVGKTEPV 70
            |||..::|::|:.|:.||..||:|||||.|.|||:.||||||||||||||||:|||||||::|.|
 Worm     4 RFYENQFPDVEETVVANVKMIADMGAYVRLSEYNDKEGMILLSELSRRRIRSVNKLIRVGRSESV 68

  Fly    71 VVIRVDKEKGYIDLSKRRVSPEDVEKCTERFAKAKAINSLLRHVADILGFEGNEKLEDLYQKTAW 135
            |||||||:|||||||||||..:|:::|.||||.||.:||:|||||:.:|:..:|:||||||||||
 Worm    69 VVIRVDKDKGYIDLSKRRVYQKDLKQCDERFANAKMVNSILRHVAEQVGYTTDEELEDLYQKTAW 133

  Fly   136 HFEKKYNNKTVAYDIFKQSVTDPTVFDECNLEPETKEVLLSNIKRKLVSPTVKIRADIECSCYGY 200
            ||::|...|..:||.||:::|:||:.|||::..:.||.||.:|::||....||||||||.||:.|
 Worm   134 HFDRKEKRKAASYDAFKKAITEPTILDECDISADIKEKLLEDIRKKLTPQAVKIRADIEVSCFDY 198

  Fly   201 EGIDAVKASLTKGLELSTEELPIRINLIAPPLYVMTTSTTKKTDGLKALEVAIEHIRAKTSEYDG 265
            :|||||||:|..|...|....||:|||||.|.:|:||.|..:..|::|:...::.|:.....:.|
 Worm   199 DGIDAVKAALIAGKNCSNGTFPIKINLIAAPHFVVTTQTLDREGGIEAVNSILDTIKNAIEGFKG 263

  Fly   266 EFKVIMAPKLVTAIDEADLARRLERAEAENAQVAGDDDEEDGADQEGM--------QFDPEKEFN 322
            :|.:....::||.||:.......:..|.|:.:   |:|||:..|.:|:        |.|.|:...
 Worm   264 KFTIKEEARIVTDIDDEKKKGDGDEDEEESEE---DEDEEEDEDDDGLMAPKGLDQQVDAEEASR 325

  Fly   323 HKGSGAGRANEEDEEEEED 341
            .....||  ::||.:||:|
 Worm   326 DNRKKAG--DDEDSDEEDD 342

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF2alpha	NP_573130.1	PTZ00248	3..295	CDD:240329	153/288 (53%)
eif-2alpha	NP_001368001.1	PTZ00248	3..276	CDD:240329	149/271 (55%)