Protein Alignment Mulk and Sphk1

DIOPT Version :9

• Sequence 1: NP_723549.1
• Gene: Mulk / 326168
• FlyBaseID: FBgn0260750
• Length: 408
• Species: Drosophila melanogaster
• Sequence 2: NP_001257740.1
• Gene: Sphk1 / 170897
• RGDID: 620048
• Length: 458
• Species: Rattus norvegicus
• Alignment Length: 390
• Identity: 95/390 - (24%)
• Similarity: 152/390 - (38%)
• Gaps: 86/390 - (22%)

  Fly    53 RPKKVLVVMNPVANKKRSEKFFKNYCEPVLHLAGYSVEILRTNHIGHAKTYV--EELATLPDAIV 115
            ||.:|||::||...|.::.|.|::...|:|..|..|.:::.|....||:..|  |||... ||:.
  Rat    88 RPCRVLVLLNPRGGKGKALKLFQSRVRPLLEEAEVSFKLMLTERQNHARELVCAEELGHW-DALA 151

  Fly   116 VAGGDGTSSEVVTGLMRR----RGNLCPITILPLGRSVQSASKRINIFG----VKDVDYVKSLS- 171
            |..|||...|||.|||.|    .....|:..|| |.|..:.:..:|.:.    |.:.|.:.:.:
  Rat   152 VMSGDGLMHEVVNGLMERPDWESAIQKPLCSLP-GGSGNALAASLNYYAGHEQVTNEDLLINCTL 215

  Fly   172 ----KALEPMLKDESQYQSVIRFDVINEEDGSNSQLKPIFGLNGLSWGLLEDIDAAKDKYWYFGP 232
                :.|.||             ::::....|..||   :.:..||||.:.|:|...:||...|.
  Rat   216 LLCCRQLSPM-------------NLLSLHTASGRQL---YSVLSLSWGFVADVDLESEKYRSLGE 264

  Fly   233 LRH----------------------YASAASKSFADNWSLKTDYVYTPPCPGCVDCAATVQRQET 275
            :|.                      ...||||..|.:.:.|     .|.....|.....|....|
  Rat   265 IRFTVGTFFRLASLRIYQGQLAYLPVGKAASKIPASSLAQK-----GPANTYLVPLEEPVPPHWT 324

  Fly   276 AQPSGLFTRGLIKYKNNPGETKRPLVKNDNCSKKFE---GSAEASQININCVQNKDNFAELESQF 337
            ..|...|...|:            |:.....::.|.   |..||..:::..::...:.|.|...|
  Rat   325 VVPEQDFVLVLV------------LLHTHLSTEMFAAPMGRCEAGVMHLFYIRAGVSRAMLLRLF 377

  Fly   338 ISSLQPGWEFIKQIPEVTCSKILPSLVVKSRTIQLHPDGEMGEKFYSIDGEEYDARPIKVSVVPN 402
            : ::|.|...     ::.|..::...||..|   |.|..:.|  .:|:|||......::..|.||
  Rat   378 L-AMQKGKHM-----DLDCPYLVHVPVVAFR---LEPRNQRG--VFSVDGELMVCEAVQGQVHPN 431

  Fly   403  402
              Rat   432  431

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mulk	NP_723549.1	LCB5	55..407	CDD:224513	93/388 (24%)
		DAGK_cat	56..>146	CDD:279163	35/95 (37%)
Sphk1	NP_001257740.1	LCB5	91..443	CDD:224513	93/387 (24%)
		DAGK_cat	91..197	CDD:279163	37/107 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1597
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810