DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Mulk and agk

DIOPT Version :9

Sequence 1:	NP_723549.1	Gene:	Mulk / 326168	FlyBaseID:	FBgn0260750	Length:	408	Species:	Drosophila melanogaster
Sequence 2:	NP_001090780.1	Gene:	agk / 100037870	XenbaseID:	XB-GENE-979723	Length:	428	Species:	Xenopus tropicalis

Alignment Length:	436	Identity:	124/436 - (28%)
Similarity:	203/436 - (46%)	Gaps:	66/436 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 RVIRNNWKKCTFGAAVSVYALQALKTHIEIEQH----MREFASNIQANWISDR--P----KKVLV 59
            :.:||:|||.|.|     :.|.|..:|....:|    :|..|......:.:.|  |    ||..|
Frog     9 KTLRNHWKKSTVG-----FCLLAYGSHWMYGKHCDNLLRRAACEEAQVFGNHRILPNSAIKKATV 68

  Fly    60 VMNPVANKKRSEKFFKNYCEPVLHLAGYSVEILRTNHIGHAKTYVEELATLPDAIVVAGGDGTSS 124
            .:||.|.|.::...|:....|||||||..:.:::|::.|.||..: ||....|.|:|||||||..
Frog    69 FLNPAACKGKARTLFEKNAAPVLHLAGIDITVVKTDYEGQAKKLL-ELMEKTDLIIVAGGDGTLQ 132

  Fly   125 EVVTGLMRRRG----NLCPITILPLGRSVQSASKRINIFGVKDVDYVKSLSKALEPMLKDESQYQ 185
            ||:|||:||..    :..||..:||| ...:.|:  .::..:: :.|:.:::|...:||.|:...
Frog   133 EVITGLLRREDQASFSKVPIGFIPLG-GTNTLSR--TLYPERE-NKVQQITEATLSILKGETVPL 193

  Fly   186 SVIRFDVINEEDGSNSQLKPIFGLNGLSWGLLEDIDAAKDKYWYFGPLRHYAS---AASKSFADN 247
            .|::  :..|:|      :|:|.:.|:.||...|......||||.|||:..|:   :|.|.:...
Frog   194 DVLK--IKGEQD------QPVFAMQGIRWGSYRDASVKASKYWYLGPLKARAAHMFSALKEWPQQ 250

  Fly   248 WSLKTDYV---YTPPCPGCVDCAATVQRQETAQPSGL-FTRGLIKYKNNPGETKRPLVKNDNCSK 308
            ......|:   ..||        ...:::.|..|..: ..|.|..|.:.|    :..|..:...:
Frog   251 HQASILYLGPAERPP--------EEPEQKPTRPPLHVRIYRRLALYWSPP----KVEVPAEPVPE 303

  Fly   309 KFEGSAEASQININ-CVQN--KDNFAELESQFISSLQPG----WEFIKQIPEVTCSKIL---PSL 363
            .:| .|:.|.:.:: ..||  .|....|:|..| |::|.    .|||....:.....:|   .|.
Frog   304 PWE-EAQLSAVEVSITTQNHQPDLMRTLDSMSI-SIEPDTISKGEFIHLGAQKMADPLLHPGDSQ 366

  Fly   364 VVKSRTIQLH-PDGEMGEKFYSIDGEEYDARPIKVSVVPNAIKVFC 408
            |:.:....|| |.|..|.  :|||.|||:|..::|:::|..:...|
Frog   367 VLLASRCSLHLPQGTEGH--FSIDSEEYEAMSVEVTLLPRKLHFLC 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mulk	NP_723549.1	LCB5	55..407	CDD:224513	108/373 (29%)
Mulk	NP_723549.1	DAGK_cat	56..>146	CDD:279163	39/93 (42%)
agk	NP_001090780.1	DAGK_cat	65..198	CDD:279163	48/139 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	47	1.000	Domainoid score	I11906
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H41239
Inparanoid	1	1.050	115	1.000	Inparanoid score	I4675
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1312024at2759
OrthoFinder	1	1.000	-	-		FOG0006608
OrthoInspector	1	1.000	-	-		oto104553
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6357
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	8.060