Protein Alignment ZnT33D and COT1

DIOPT Version :9

• Sequence 1: NP_723732.2
• Gene: ZnT33D / 326167
• FlyBaseID: FBgn0051860
• Length: 701
• Species: Drosophila melanogaster
• Sequence 2: NP_014961.3
• Gene: COT1 / 854494
• SGDID: S000005843
• Length: 439
• Species: Saccharomyces cerevisiae
• Alignment Length: 412
• Identity: 94/412 - (22%)
• Similarity: 172/412 - (41%)
• Gaps: 83/412 - (20%)

  Fly   337 ARRVLIIACILC-TIFLILEVIGGILSNSLAIATDAAHLLTDLASFLISISALHLA-GRPSSERL 399
            :::|.||:.:|. |:|..:|:..|.||:|||:..|:.|:|.|:.|.::::.|:::| .|......
Yeast     5 SKQVKIISLLLLDTVFFGIEITTGYLSHSLALIADSFHMLNDIISLVVALWAVNVAKNRNPDSTY 69

  Fly   400 NYGWHRAEVIGAMV-SIFFIWVVTGILVYMAIMRWVNQDFELDAKIMLITSALAILFNVIMAMQL 463
            .|||.|||::||:: ::|.|.:...||: .|:.|.:......:.|.:|......::.|.:.....
Yeast    70 TYGWKRAEILGALINAVFLIALCVSILI-EALQRIIAPPVIENPKFVLYVGVAGLISNTVGLFLF 133

  Fly   464 Q-------HGHSHSLPGV---HKM-----------------------SKD----------AGSVL 485
            .       |||.||..|:   |:|                       |.|          ..|.:
Yeast   134 HDNDQEHGHGHGHSHGGIFADHEMHMPSSHTHTHAHVDGIENTTPMDSTDNISEIMPNAIVDSFM 198

  Fly   486 GSKMILLLGKSVSM--QYAAKGH---------------ENINVRAAIIHVVGDIIQSFGVFVAAL 533
            .....||..::.|.  .|:...|               .::|:....:||:||.:.:.||.::|
Yeast   199 NENTRLLTPENASKTPSYSTSSHTIASGGNYTEHNKRKRSLNMHGVFLHVLGDALGNIGVMLSA- 262

  Fly   534 IIFFWP---EWA-FMDSVCTFVFSVLVLVVTFKILRDVLMVLMEATPDFMDYEEVKQTFLSISGV 594
             .|.|.   .|. :.|.:.:.:.:.::......:......:|::|||..:..::|:...|.|.|:
Yeast   263 -FFIWKTDYSWKYYTDPLVSLIITGIIFSSALPLSCKASKILLQATPSTLSGDQVEGDLLKIPGI 326

  Fly   595 EHVHNLRIWALSINKVALSAHLAISKDADPQLILEEATTLIHK--RFKFFETTIQ---IEEYSPG 654
            ..:|:..||.|:.:....|.|:.:  |..|:...:.|..:..|  |:.....|:|   |......
Yeast   327 IAIHDFHIWNLTESIFIASLHIQL--DISPEQFTDLAKIVRSKLHRYGIHSATLQPEFITREVTS 389

  Fly   655 MENCGQCLSPSDKSGKRKSSDP 676
            .|..|      |..|....:||
Yeast   390 TERAG------DSQGDHLQNDP 405

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZnT33D	NP_723732.2	CDF	350..651	CDD:273544	83/371 (22%)
		Cation_efflux	350..572	CDD:279834	61/287 (21%)
COT1	NP_014961.3	CzcD	9..384	CDD:224151	86/379 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1230
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810