Protein Alignment ZnT33D and SLC30A1

DIOPT Version :9

• Sequence 1: NP_723732.2
• Gene: ZnT33D / 326167
• FlyBaseID: FBgn0051860
• Length: 701
• Species: Drosophila melanogaster
• Sequence 2: NP_067017.2
• Gene: SLC30A1 / 7779
• HGNCID: 11012
• Length: 507
• Species: Homo sapiens
• Alignment Length: 459
• Identity: 103/459 - (22%)
• Similarity: 185/459 - (40%)
• Gaps: 131/459 - (28%)

  Fly   343 IACILCT--IFLILEVIGGILSNSLAIATDAAHLLTDLASFLISISALHLAGRPSSERLN-YGWH 404
            :.|:|..  :|::|||:...:::|||:.:|:.|:|:|:.:.::::.|...|.|..:.:.| :||.
Human    11 LLCMLALTFMFMVLEVVVSRVTSSLAMLSDSFHMLSDVLALVVALVAERFARRTHATQKNTFGWI 75

  Fly   405 RAEVIGAMVSIFFIWVVTGILVYMAIMRWVNQDFELDAKIMLITSALA-ILFNVIMAMQLQ---- 464
            ||||:||:|:..|:..:...::..||.|:: :..|:...::::...:| :|.||:......
Human    76 RAEVMGALVNAIFLTGLCFAILLEAIERFI-EPHEMQQPLVVLGVGVAGLLVNVLGLCLFHHHSG 139

  Fly   465 -------------HGHSHSLP------GVHKMSKDAGSVLGSK---------MILLLGKSVSMQY 501
                         |||.|.||      .....|.|.....|.:         ::.....|..::.
Human   140 FSQDSGHGHSHGGHGHGHGLPKGPRVKSTRPGSSDINVAPGEQGPDQEETNTLVANTSNSNGLKL 204

  Fly   502 AAKGHEN-------------------------------INVRAAIIHVVGDIIQSFGVFVAALII 535
            .....||                               :|:|...:||:||.:.|..|.|.||:.
Human   205 DPADPENPRSGDTVEVQVNGNLVREPDHMELEEDRAGQLNMRGVFLHVLGDALGSVIVVVNALVF 269

  Fly   536 FF-W------------------------------------PEWA-FMDSVCTFVFSVLVLVVTFK 562
            :| |                                    |.|. ::|.....|...::|..|:.
Human   270 YFSWKGCSEGDFCVNPCFPDPCKAFVEIINSTHASVYEAGPCWVLYLDPTLCVVMVCILLYTTYP 334

  Fly   563 ILRDVLMVLMEATPDFMDYEEVKQTFLSISGVEHVHNLRIWALSINKVALSAHLAISKDADPQLI 627
            :|::..::|::..|..:|...:.:...::.|||.||.|.:|.|:.:::..:||:   |..||...
Human   335 LLKESALILLQTVPKQIDIRNLIKELRNVEGVEEVHELHVWQLAGSRIIATAHI---KCEDPTSY 396

  Fly   628 LEEATTL--IHKRFKFFETTIQIEEYSPGMEN------------CG--QCLS--PSDKSGKRKSS 674
            :|.|.|:  :........||||.|..|.|.::            |.  ||..  |...|||
Human   397 MEVAKTIKDVFHNHGIHATTIQPEFASVGSKSSVVPCELACRTQCALKQCCGTLPQAPSGK---- 457

  Fly   675 DPEK 678
            |.||
Human   458 DAEK 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZnT33D	NP_723732.2	CDF	350..651	CDD:273544	89/405 (22%)
		Cation_efflux	350..572	CDD:279834	65/324 (20%)
SLC30A1	NP_067017.2	CzcD	6..423	CDD:224151	91/415 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	142..217		12/74 (16%)
		6 X 2 AA approximate repeats of H-G	146..158		3/11 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1230
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810