DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ZnT33D and Slc30a10

DIOPT Version :9

Sequence 1:	NP_723732.2	Gene:	ZnT33D / 326167	FlyBaseID:	FBgn0051860	Length:	701	Species:	Drosophila melanogaster
Sequence 2:	NP_001099455.1	Gene:	Slc30a10 / 289353	RGDID:	1305098	Length:	472	Species:	Rattus norvegicus

Alignment Length:	392	Identity:	93/392 - (23%)
Similarity:	162/392 - (41%)	Gaps:	69/392 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   341 LIIACILCTIFLILEVIGGILSNSLAIATDAAHLLTDLASFLISISALHLAGR-PSSERLNYGWH 404
            |:...:|...|.:.|::.|.|.||:|:.:|:.::|:||.|..:.:.:.::|.| |......||:.
  Rat    11 LLFMLVLTAAFFVAELVSGYLGNSIALLSDSFNMLSDLISLCVGLGSGYIARRGPRGSSATYGYV 75

  Fly   405 RAEVIGAMVSIFFIWVVTGILVYMAIMRWVNQDFELDAKIMLITSALAILFNVIMAMQLQ----- 464
            ||||:||:.:..|:..:...:...|::|....:...|.:::||..||.:..||:..:..|
  Rat    76 RAEVVGALSNAVFLTALCFTIFVEAVLRLARPERIDDPELVLIVGALGLAVNVVGLLIFQDCGAC 140

  Fly   465 -----HGHSHSLPGVHKMSKDAGSVLG-------------SKMILLLGKSV--SMQYAA------ 503
                 .|| .:.|.......|.|..||             ...:.|.|.|.  ..|..|
  Rat   141 FSRCTRGH-RTRPSQPPRQGDTGGALGCPREAATATDPGSDSAVTLRGASAGRKQQEGATVFSNV 204

  Fly   504 ------------------KGHENINVRAAIIHVVGDIIQSFGVFVAALIIFFWP-------EW-A 542
                              |..|.:|:|..::||:||.:.|..|.|.|:|.:..|       .| .
  Rat   205 AGDSLNTQNEPEETTKKEKKSEALNIRGVLLHVMGDALGSVIVVVTAIIFYVRPLRHEDPCNWQC 269

  Fly   543 FMDSVCTFVFSVLVLVVTFKILRDVLMVLMEATPDFMDYEEVKQTFLSISGVEHVHNLRIWALSI 607
            ::|...|.|..:::|...|.::::..::|::..|..::.||:......:.||..||.:.||.|..
  Rat   270 YIDPSLTVVMVIIILSSAFPLIKETAVILLQMVPKGVNMEELMSQLSMVPGVSSVHEVHIWELIS 334

  Fly   608 NKVALSAHLAISKDADPQLILEEATTLIHKRFKFFETTIQIE--------EYSPGMENC-GQCLS 663
            .||..:.|:...:..:.|....:...:.| .......|||.|        |....:..| ..|:|
  Rat   335 GKVIATLHIKHQEGTEYQDASRKVREIFH-HAGIHNVTIQFETLDLKEALEQKDFLPTCSAPCIS 398

  Fly   664 PS 665
            .|
  Rat   399 QS 400

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ZnT33D	NP_723732.2	CDF	350..651	CDD:273544	86/366 (23%)
ZnT33D	NP_723732.2	Cation_efflux	350..572	CDD:279834	66/279 (24%)
Slc30a10	NP_001099455.1	CzcD	10..376	CDD:224151	87/366 (24%)
Slc30a10	NP_001099455.1	Cation_efflux	20..299	CDD:279834	66/279 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166345950
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1230
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740