Protein Alignment ZnT33D and Slc30a8

DIOPT Version :9

• Sequence 1: NP_723732.2
• Gene: ZnT33D / 326167
• FlyBaseID: FBgn0051860
• Length: 701
• Species: Drosophila melanogaster
• Sequence 2: NP_766404.1
• Gene: Slc30a8 / 239436
• MGIID: 2442682
• Length: 367
• Species: Mus musculus
• Alignment Length: 355
• Identity: 135/355 - (38%)
• Similarity: 205/355 - (57%)
• Gaps: 49/355 - (13%)

  Fly   323 HCHFKERETGVDKAARRV-----LIIACILCTIFLILEVIGGILSNSLAIATDAAHLLTDLASFL 382
            |||...:.|| ::::::.     |..|..:|.||::.||:||.::.||||.|||||||.||.|||
Mouse    51 HCHNSAKATG-NRSSKQAHAKWRLCAASAICFIFMVAEVVGGHVAGSLAILTDAAHLLIDLTSFL 114

  Fly   383 ISISALHLAGRPSSERLNYGWHRAEVIGAMVSIFFIWVVTGILVYMAIMRWVNQDFELDAKIMLI 447
            :|:.:|.|:.||.|:||.:||:|||::||::|:..||||||:|:|:|..|.:..|:::.|.||:.
Mouse   115 LSLFSLWLSSRPPSKRLTFGWYRAEILGALLSVLCIWVVTGVLLYLACERLLYPDYQIQAGIMIT 179

  Fly   448 TSALAILFNVIMAM---QLQHGHSHSLPGVHKMSKDAGSVLGSKMILLLGKSVSMQYAAKGHENI 509
            .|..|:..|:::.|   |...|::|         ||.                        ..|.
Mouse   180 VSGCAVAANIVLTMILHQRNFGYNH---------KDV------------------------QANA 211

  Fly   510 NVRAAIIHVVGDIIQSFGVFVAALIIFFWPEWAFMDSVCTFVFSVLVLVVTFKILRDVLMVLMEA 574
            :||||.:|.:||:.||..|.::||||:|.|::...|.||||:||:|||..|..||:|..::|||.
Mouse   212 SVRAAFVHALGDVFQSISVLISALIIYFKPDYKIADPVCTFIFSILVLASTVMILKDFSILLMEG 276

  Fly   575 TPDFMDYEEVKQTFLSISGVEHVHNLRIWALSINKVALSAHLAISKDADPQLI---LEEATTLIH 636
            .|..:.|..||:..|::.||..||:|.||:|::|:|.||.|:|.:...|.|.:   :.:|.:
Mouse   277 VPKGLSYNSVKEIILAVDGVISVHSLHIWSLTVNQVILSVHVATAASQDSQSVRTGIAQALS--- 338

  Fly   637 KRFKFFETTIQIEEYSPGMENCGQCLSPSD 666
             .|.....|||||..:....:|..|..|.|
Mouse   339 -SFDLHSLTIQIESAADQDPSCLLCEDPQD 367

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZnT33D	NP_723732.2	CDF	350..651	CDD:273544	123/306 (40%)
		Cation_efflux	350..572	CDD:279834	92/224 (41%)
Slc30a8	NP_766404.1	CDF	82..352	CDD:273544	123/306 (40%)
		Cation_efflux	82..273	CDD:279834	92/223 (41%)
		HXXXXX[HY]NH. /evidence=ECO:0000250	196..204		2/7 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1230
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D351752at33208
OrthoFinder	1	1.000	-	-		FOG0000470
OrthoInspector	1	1.000	-	-		otm43512
orthoMCL	1	0.900	-	-		OOG6_100508
Panther	1	1.100	-	-	O	PTHR11562
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X541
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	10	9.780