Protein Alignment ZnT33D and SLC30A8

DIOPT Version :9

• Sequence 1: NP_723732.2
• Gene: ZnT33D / 326167
• FlyBaseID: FBgn0051860
• Length: 701
• Species: Drosophila melanogaster
• Sequence 2: NP_776250.2
• Gene: SLC30A8 / 169026
• HGNCID: 20303
• Length: 369
• Species: Homo sapiens
• Alignment Length: 351
• Identity: 140/351 - (39%)
• Similarity: 206/351 - (58%)
• Gaps: 40/351 - (11%)

  Fly   323 HCH--FKERETGVDK--AARRVLIIACILCTIFLILEVIGGILSNSLAIATDAAHLLTDLASFLI 383
            |||  .|..|.|.::  .|:..|..|..:|.||:|.||:||.::.|||:.|||||||.||.|||:
Human    52 HCHSGSKPTEKGANEYAYAKWKLCSASAICFIFMIAEVVGGHIAGSLAVVTDAAHLLIDLTSFLL 116

  Fly   384 SISALHLAGRPSSERLNYGWHRAEVIGAMVSIFFIWVVTGILVYMAIMRWVNQDFELDAKIMLIT 448
            |:.:|.|:.:|.|:||.:||||||::||::||..||||||:|||:|..|.:..|:::.|.:|:|.
Human   117 SLFSLWLSSKPPSKRLTFGWHRAEILGALLSILCIWVVTGVLVYLACERLLYPDYQIQATVMIIV 181

  Fly   449 SALAILFNVIMAMQLQH---GHSHSLPGVHKMSKDAGSVLGSKMILLLGKSVSMQYAAKGHENIN 510
            |:.|:..|:::.:.|..   ||:|                         |.|        ..|.:
Human   182 SSCAVAANIVLTVVLHQRCLGHNH-------------------------KEV--------QANAS 213

  Fly   511 VRAAIIHVVGDIIQSFGVFVAALIIFFWPEWAFMDSVCTFVFSVLVLVVTFKILRDVLMVLMEAT 575
            ||||.:|.:||:.||..|.::||||:|.||:...|.:|||:||:|||..|..||:|..::|||..
Human   214 VRAAFVHALGDLFQSISVLISALIIYFKPEYKIADPICTFIFSILVLASTITILKDFSILLMEGV 278

  Fly   576 PDFMDYEEVKQTFLSISGVEHVHNLRIWALSINKVALSAHLAISKDADPQLILEEATTLIHKRFK 640
            |..::|..||:..|::.||..||:|.||:|::|:|.||||:|.:...|.|::..|....:.|.|.
Human   279 PKSLNYSGVKELILAVDGVLSVHSLHIWSLTMNQVILSAHVATAASRDSQVVRREIAKALSKSFT 343

  Fly   641 FFETTIQIEEYSPGMENCGQCLSPSD 666
            ....|||:|.......:|..|..|.|
Human   344 MHSLTIQMESPVDQDPDCLFCEDPCD 369

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZnT33D	NP_723732.2	CDF	350..651	CDD:273544	126/303 (42%)
		Cation_efflux	350..572	CDD:279834	94/224 (42%)
SLC30A8	NP_776250.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	31..52		140/351 (40%)
		CDF	83..353	CDD:273544	125/302 (41%)
		Cation_efflux	83..274	CDD:279834	94/223 (42%)
		HXXXXX[HY]NH-motif	197..205		2/7 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	186	1.000	Domainoid score	I3351
eggNOG	1	0.900	-	-		E1_COG1230
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D351752at33208
OrthoFinder	1	1.000	-	-		FOG0000470
OrthoInspector	1	1.000	-	-		otm41461
orthoMCL	1	0.900	-	-		OOG6_100508
Panther	1	1.100	-	-	O	PTHR11562
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X541
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	10	9.780