Protein Alignment ZnT33D and SLC30A7

DIOPT Version :9

• Sequence 1: NP_723732.2
• Gene: ZnT33D / 326167
• FlyBaseID: FBgn0051860
• Length: 701
• Species: Drosophila melanogaster
• Sequence 2: NP_001138356.1
• Gene: SLC30A7 / 148867
• HGNCID: 19306
• Length: 376
• Species: Homo sapiens
• Alignment Length: 342
• Identity: 75/342 - (21%)
• Similarity: 151/342 - (44%)
• Gaps: 64/342 - (18%)

  Fly   334 DKAARRVLIIACILCTIFLILEVIGGILSNSLAIATDAAHLLTDLASFLISISALHLAGRPSSER 398
            ||.:|.:....|:..: |..:|::.||.||.|.:.:|:.|:..|..:.|..::|..::....::.
Human    32 DKTSRNLFFFLCLNLS-FAFVELLYGIWSNCLGLISDSFHMFFDSTAILAGLAASVISKWRDNDA 95

  Fly   399 LNYGWHRAEVIGAMVSIFFIWVVTGILVYMAIMRWVNQDFELDAKIMLITSALAILFNVIMAMQL 463
            .:||:.||||:...|:..|: :.|...::...:.......::..:.:|:.|.|..:.|:|.....
Human    96 FSYGYVRAEVLAGFVNGLFL-IFTAFFIFSEGVERALAPPDVHHERLLLVSILGFVVNLIGIFVF 159

  Fly   464 QH-GHSHSLPGVHKMSKDAGSVLGSKMILLLG------------KSVSMQY-AAKGHENIN---- 510
            :| ||.||    |      ||..|....|..|            .|..::: ||..|::.:
Human   160 KHGGHGHS----H------GSGHGHSHSLFNGALDQAHGHVDHCHSHEVKHGAAHSHDHAHGHGH 214

  Fly   511 -------------------VRAAIIHVVGDIIQSFGVFVAALIIFFWPEWAFM--DSVCTFVFSV 554
                               ::...:|::.|.:.|.||..:|:::   ..:..|  |.:|:.:.::
Human   215 FHSHDGPSLKETTGPSRQILQGVFLHILADTLGSIGVIASAIMM---QNFGLMIADPICSILIAI 276

  Fly   555 LVLVVTFKILRDVLMVLMEATPDFMD------YEEVKQTFLSISGVEHVHNLRIWALSINKVALS 613
            |::|....:||:.:.:||:.||..::      |:.|:|    :.||..:.....|.|..:....:
Human   277 LIVVSVIPLLRESVGILMQRTPPLLENSLPQCYQRVQQ----LQGVYSLQEQHFWTLCSDVYVGT 337

  Fly   614 AHLAISKDADPQLILEE 630
            ..|.::.|||.:.||.:
Human   338 LKLIVAPDADARWILSQ 354

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZnT33D	NP_723732.2	CDF	350..651	CDD:273544	71/326 (22%)
		Cation_efflux	350..572	CDD:279834	54/260 (21%)
SLC30A7	NP_001138356.1	CzcD	31..374	CDD:224151	75/342 (22%)
		Cation_efflux	48..294	CDD:279834	54/259 (21%)
		His-rich loop	161..218		15/66 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	194..226		4/31 (13%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1230
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810