DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tap42 and TAP42

DIOPT Version :9

Sequence 1:	NP_723811.1	Gene:	Tap42 / 326166	FlyBaseID:	FBgn0051852	Length:	380	Species:	Drosophila melanogaster
Sequence 2:	NP_013741.1	Gene:	TAP42 / 855043	SGDID:	S000004630	Length:	366	Species:	Saccharomyces cerevisiae

Alignment Length:	386	Identity:	94/386 - (24%)
Similarity:	156/386 - (40%)	Gaps:	71/386 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 ELEVTELPFNGSEFQN-KVKTAMGLFEQATVIVNQVSMFSANELIDEVSTESLPFMLLPYFLGKL 90
            :||.|.|..:..|:|. .:.|...|....|.|.:::::||.||.||:|||.|:.|:.:.|:||.|
Yeast    18 KLEHTSLRQDSPEYQGLLLSTIKKLLNLKTAIFDRLALFSTNETIDDVSTASIKFLAVDYYLGLL 82

  Fly    91 TTKINSPNN----THSIELGEIYFK-------DHLQRCQEYDLC----------AAPKSQVAKAD 134
            .::..|.::    ..|::|  ||.|       :.|...|:|.|.          ...:.....::
Yeast    83 ISRRQSNDSDVAQRQSMKL--IYLKKSVESFINFLTLLQDYKLLDPLVGEKLGNFKDRYNPQLSE 145

  Fly   135 SQAEKSEQRELVEAAFNRNDKIAQYRRMKEIDEYMARMRDAVKNKTVD---DEDKRVFFLKYLDK 196
            ..|:....::|..|...|.:||..::|.|||...:..:...:||...|   ||..|..:|..|..
Yeast   146 LYAQPKNNKDLSGAQLKRKEKIELFQRNKEISTKLHCLELELKNNDEDHDHDELLRELYLMRLHH 210

  Fly   197 SIIDSKQELETLGVMKQLAQMRLARLAGGESDNEVDSFRPPNQNQSSASSTSRGHGHSHGPGHHH 261
            ..:|:...:|     :.|.:..:.......|.:||         :||.:...:........|...
Yeast   211 FSLDTINNIE-----QNLFECEMLSNFLKNSVHEV---------KSSGTQIRKESNDDDSTGFTD 261

  Fly   262 HHQQAAKP------KPLQPFIIT--RNATQKAVFGLGYPSLPIMTVDEFYQQRVDEGIFPDEEKV 318
            ..:...||      :.|:.|.:.  |...|:.|.|.|... |.|:|:||..:..:||
Yeast   262 KLENINKPLIDKKGQVLRNFTLVDKRQQLQQKVRGYGQYG-PTMSVEEFLDKEFEEG-------- 317

  Fly   319 AKMNQAQAIAAARDPNEKEDEEKAVEELQAEQDDPEYIDRMRRMDEYKDVVRRGDGNRHNR 379
                  :.:....:|.:..|||.     ...||...|  :.|..||:|:...:|.||..||
Yeast   318 ------RVLQGGEEPEQAPDEEN-----MDWQDRETY--KAREWDEFKESHAKGSGNTMNR 365

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tap42	NP_723811.1	TAP42	14..367	CDD:282084	88/372 (24%)
TAP42	NP_013741.1	TAP42	4..355	CDD:398032	89/374 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342090
Domainoid	1	1.000	62	1.000	Domainoid score	I2503
eggNOG	1	0.900	-	-		E1_KOG2830
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I1700
Isobase	1	0.950	-	0	Normalized mean entropy	S3266
OMA	1	1.010	-	-		QHG54512
OrthoFinder	1	1.000	-	-		FOG0003127
OrthoInspector	1	1.000	-	-		oto100073
orthoMCL	1	0.900	-	-		OOG6_102570
Panther	1	1.100	-	-	LDO	PTHR10933
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1748
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.740