DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31826 and Ttpa

DIOPT Version :9

Sequence 1:	NP_001260473.1	Gene:	CG31826 / 326164	FlyBaseID:	FBgn0051826	Length:	268	Species:	Drosophila melanogaster
Sequence 2:	NP_037180.1	Gene:	Ttpa / 25571	RGDID:	3915	Length:	278	Species:	Rattus norvegicus

Alignment Length:	247	Identity:	66/247 - (26%)
Similarity:	110/247 - (44%)	Gaps:	40/247 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 DTLLTKFLHYTRWDTIKAYQAIHDYYEFKRRHPTWVA-RHPIEHYRQLFYGTHCRYVMPQADRSG 100
            |..|.:||....:|...|::.:.:||:::...|...| .||......|..|.|  .|:...|.:|
  Rat    49 DAFLLRFLRARDFDLDLAWRLMKNYYKWRAECPELSADLHPRSILGLLKAGYH--GVLRSRDPTG 111

  Fly   101 -RVLV---------VFKTVDGFQDYPDYLQSLVEMDDLIFESLLLLPRVQQNGITVICDLQGTNR 155
             |||:         ||...|.|:      .||: ..:||.:.:    ..|:||:..|.||:|...
  Rat   112 SRVLIYRISYWDPKVFTAYDVFR------VSLI-TSELIVQEV----ETQRNGVKAIFDLEGWQI 165

  Fly   156 NFLRQFSPAFMK----VVNEKNGVLPFSQRIVHIIQRGFLMHVTSTLFMPFMNKEFKEKIFTHDG 216
            :...|.:|:..|    ||.:.   .|...|.:|:|....:.|...::..||:.::.|.:|..|..
  Rat   166 SHAFQITPSVAKKIAAVVTDS---FPLKVRGIHLINEPVIFHAVFSMIKPFLTEKIKGRIHLHGN 227

  Fly   217 RHLSKLREMVGYESLPAEYGGPATNVLD-----TNLIF---NHLSQNAEYLE 260
            .:.|.|.:... :.||.||||..:::.|     ||.|.   ::||..:|.::
  Rat   228 NYKSSLLQHFP-DILPLEYGGNESSMEDICQEWTNFIMKSEDYLSSISETIQ 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31826	NP_001260473.1	CRAL_TRIO_N	17..61	CDD:215024	6/23 (26%)
CG31826	NP_001260473.1	CRAL_TRIO	92..237	CDD:279044	42/158 (27%)
Ttpa	NP_037180.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..22
		CRAL_TRIO_N	25..73	CDD:215024	6/23 (26%)
		CRAL_TRIO	99..248	CDD:395525	45/165 (27%)
		Phosphatidylinositol 3,4-bisphosphate binding. /evidence=ECO:0000250\|UniProtKB:Q8BWP5	190..192		0/1 (0%)
		Phosphatidylinositol 4,5-bisphosphate binding. /evidence=ECO:0000250\|UniProtKB:Q8BWP5	208..211		0/2 (0%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10174
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910