DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31826 and Sec14l2

DIOPT Version :9

Sequence 1:	NP_001260473.1	Gene:	CG31826 / 326164	FlyBaseID:	FBgn0051826	Length:	268	Species:	Drosophila melanogaster
Sequence 2:	NP_446253.2	Gene:	Sec14l2 / 116486	RGDID:	621779	Length:	403	Species:	Rattus norvegicus

Alignment Length:	262	Identity:	59/262 - (22%)
Similarity:	104/262 - (39%)	Gaps:	39/262 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LTARV-DHTAEQIFKIEQLRQLVEKCEDLRVGTEDTLLTKFLHYTRWDTIKAYQAIHDYYEFKRR 67
            ::.|| |.:.:|...:.:.|:.|:.........:|..|.::|....:|..|:...:..:.||:::
  Rat     1 MSGRVGDLSPKQEEALAKFRENVQDVLPALPNPDDYFLLRWLRARSFDLQKSEAMLRKHVEFRKQ 65

  Fly    68 HP-----TWVARHPIEHYRQLFYGTHCRYVMPQADRSGRVLVVFKTVDGFQDYPDYLQSLVEMDD 127
            ..     :|   .|.|..:|...|..|.|     |..|  ..|:..:.|..|....|.|..:.|.
  Rat    66 KDIDKIISW---QPPEVIQQYLSGGRCGY-----DLDG--CPVWYDIIGPLDAKGLLFSASKQDL 120

  Fly   128 LIFE----SLLLLPRVQQNG--------ITVICDLQGTNRNFLRQFSPA------FMKVVNEKNG 174
            |..:    .|||.....|..        ||:|.|.:|.....|  :.||      |:.:..|.
  Rat   121 LRTKMRDCELLLQECTHQTAKLGKKIETITMIYDCEGLGLKHL--WKPAVEAYGEFLTMFEEN-- 181

  Fly   175 VLPFSQRIVHIIQRGFLMHVTSTLFMPFMNKEFKEKIFTHDGRHLSKLREMVGYESLPAEYGGPA 239
             .|.:.:.:.:::...|..|...|..||::::.::||..........|.:.:..:.||.||||..
  Rat   182 -YPETLKRLFVVKAPKLFPVAYNLIKPFLSEDTRKKIMVLGANWKEVLLKHISPDQLPVEYGGTM 245

  Fly   240 TN 241
            |:
  Rat   246 TD 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31826	NP_001260473.1	CRAL_TRIO_N	17..61	CDD:215024	7/43 (16%)
CG31826	NP_001260473.1	CRAL_TRIO	92..237	CDD:279044	36/162 (22%)
Sec14l2	NP_446253.2	CRAL_TRIO_N	13..59	CDD:215024	7/45 (16%)
		SEC14	76..244	CDD:214706	43/179 (24%)
		GOLD_2	300..381	CDD:290608
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810