DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31826 and Sec14l4

DIOPT Version :9

Sequence 1:	NP_001260473.1	Gene:	CG31826 / 326164	FlyBaseID:	FBgn0051826	Length:	268	Species:	Drosophila melanogaster
Sequence 2:	NP_666125.1	Gene:	Sec14l4 / 103655	MGIID:	2144095	Length:	403	Species:	Mus musculus

Alignment Length:	250	Identity:	53/250 - (21%)
Similarity:	101/250 - (40%)	Gaps:	43/250 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 EQLRQLVEKCEDL---RVGTEDTLLTKFLHYTRWDTIKAYQAIHDYYEFKRRHP-----TWVARH 75
            |.|.:..|..:||   ....:|..|.::|....:|..|:...:..:.||:.:..     ||.|..
Mouse    14 EALARFRETLQDLLPTLPKADDYFLLRWLRARNFDLKKSEDMLRKHVEFRNQQNLDQILTWQAPE 78

  Fly    76 PIEHYRQLFYGTHCRY----------VMPQADRSGRVLVVFKTVDGFQDYPDYLQSLVEMDDLIF 130
            .|:.|..   |....|          ::...|..|..:...|        .|.::..:::.:::.
Mouse    79 VIQLYDS---GGLSGYDYEGCPVWFDIIGTMDPKGLFMSASK--------QDMIRKRIKVCEMLL 132

  Fly   131 ESLLLLPRVQQNG-----ITVICDLQGTNRNFLRQFSPAFMKVVNEKNGVL----PFSQRIVHII 186
            ....|  :.|:.|     :.::.|::|.:...|  :.|| ::|..:...:|    |.:.:.:.||
Mouse   133 HECEL--QSQKLGRKIERMVMVFDMEGLSLRHL--WKPA-VEVYQQFFAILEANYPETVKNLIII 192

  Fly   187 QRGFLMHVTSTLFMPFMNKEFKEKIFTHDGRHLSKLREMVGYESLPAEYGGPATN 241
            :...|..|...|...||.:|.::||....|....:|.:.|..:.||.|:||..|:
Mouse   193 RAPKLFPVAFNLVKSFMGEETQKKIVILGGNWKQELVKFVSPDQLPVEFGGTMTD 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31826	NP_001260473.1	CRAL_TRIO_N	17..61	CDD:215024	10/44 (23%)
CG31826	NP_001260473.1	CRAL_TRIO	92..237	CDD:279044	31/153 (20%)
Sec14l4	NP_666125.1	CRAL_TRIO_N	13..59	CDD:215024	10/44 (23%)
		SEC14	77..244	CDD:214706	36/182 (20%)
		GOLD_2	284..379	CDD:290608
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810