DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31823 and Scpep1

DIOPT Version :9

Sequence 1:	NP_723939.1	Gene:	CG31823 / 326163	FlyBaseID:	FBgn0051823	Length:	427	Species:	Drosophila melanogaster
Sequence 2:	NP_083299.3	Gene:	Scpep1 / 74617	MGIID:	1921867	Length:	452	Species:	Mus musculus

Alignment Length:	443	Identity:	152/443 - (34%)
Similarity:	232/443 - (52%)	Gaps:	57/443 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 RIWACALCFFLSLICVQGRVGLGP-GVQEWDYVEVRKGAHLFYWLLYTTANVSHFIERPLVIWLQ 72
            |:|...|.|.|............| |.:.||||.|||.||:|:||.|.|....:|.|.|||:|||
Mouse    11 RLWLLLLSFLLGFSAGSAIDWREPEGKEVWDYVTVRKDAHMFWWLYYATNPCKNFSELPLVMWLQ 75

  Fly    73 GGPGVASTGSGIFEQLGPIDIEGKTRESSWLKHVNVLFVDSPVGTGFAYVEHHSLYARNNRQIAL 137
            ||||.:|||.|.||::||:|.:.|.|.::||:..::||||:||||||:||.....||::...:|.
Mouse    76 GGPGGSSTGFGNFEEIGPLDTQLKPRNTTWLQWASLLFVDNPVGTGFSYVNTTDAYAKDLDTVAS 140

  Fly   138 DLVQLMKQFLTKYPDFRKVPLHIFSESYGGKMAPEFALELHLAKKVGELECDLKSVVVGNPWTSP 202
            |::.|:|.|...:.:|:.||.:|||||||||||...::||:.|.:.|.::|:...|.:|:.|.||
Mouse   141 DMMVLLKSFFDCHKEFQTVPFYIFSESYGGKMAAGISVELYKAVQQGTIKCNFSGVALGDSWISP 205

  Fly   203 LDSILSYAPFLLQSGIVDDDGYRRISRLAGELAALVYGGKWLRALMKATEVQDEISASAGGVFIY 267
            :||:||:.|:|....::|:.|...:|.:|.::...|..|.:..|.....:.:..|..:..||..|
Mouse   206 VDSVLSWGPYLYSMSLLDNQGLAEVSDIAEQVLDAVNKGFYKEATQLWGKAEMIIEKNTDGVNFY 270

  Fly   268 N-------------------------TQRRVHVDEVYRYGEDPQMSDFMRSNVTKALGLGNMP-- 305
            |                         .||.|      |:.:...:|..|...:.|.|.:  :|
Mouse   271 NILTKSSPEKAMESSLEFLRSPLVRLCQRHV------RHLQGDALSQLMNGPIKKKLKI--IPED 327

  Fly   306 -VWMEQNSTVFERLSQDIFKPANQIVTKLLEETPIQVGIYSGILDLLCATPGTVNWIRRLKWRRS 369
             .|..|.|.||..:..|..|||..:|.||| ...:.|.:|:|.|||:..|.|..:|:::|||.:.
Mouse   328 ISWGAQASYVFLSMEGDFMKPAIDVVDKLL-AAGVNVTVYNGQLDLIVDTIGQESWVQKLKWPQL 391

  Fly   370 LEY-----------AKAPRTAIRIEGMLEGYEKHGGKLSMFWVFRAGHLVQQE 411
            .::           .|:..||    ..::.||    .|:.:|:.:|||:|..:
Mouse   392 SKFNQLKWKALYTDPKSSETA----AFVKSYE----NLAFYWILKAGHMVPSD 436

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31823	NP_723939.1	Peptidase_S10	26..425	CDD:298660	147/426 (35%)
Scpep1	NP_083299.3	Peptidase_S10	34..451	CDD:278857	147/420 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847362
Domainoid	1	1.000	312	1.000	Domainoid score	I1308
eggNOG	1	0.900	-	-		E1_COG2939
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	321	1.000	Inparanoid score	I2499
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54069
OrthoDB	1	1.010	-	-		D274674at33208
OrthoFinder	1	1.000	-	-		FOG0003531
OrthoInspector	1	1.000	-	-		otm42637
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11802
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2409
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.870