DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31823 and Cpvl

DIOPT Version :9

Sequence 1:	NP_723939.1	Gene:	CG31823 / 326163	FlyBaseID:	FBgn0051823	Length:	427	Species:	Drosophila melanogaster
Sequence 2:	XP_006506676.1	Gene:	Cpvl / 71287	MGIID:	1918537	Length:	484	Species:	Mus musculus

Alignment Length:	424	Identity:	111/424 - (26%)
Similarity:	193/424 - (45%)	Gaps:	40/424 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 FLSLICVQGRVGLG---------PGVQEWDY-----VEVRKGAHLFYWLLYTTANVSHFIERPLV 68
            |||.....|::..|         ||:.:..|     |.....::||:|.........   :.|:|
Mouse    52 FLSPYIKNGKIKEGQRKSMVSPFPGMNDKSYAGYITVNQTYNSNLFFWFFPARMQPE---DAPVV 113

  Fly    69 IWLQGGPGVASTGSGIFEQLGPIDIEGK----TRESSWLKHVNVLFVDSPVGTGFAYVEHHSLYA 129
            :||||||| .|:..|:|.:.||..|...    .|:..|...:::|::|:||||||::.:|...||
Mouse   114 LWLQGGPG-GSSMFGLFVEHGPYIITSNMTVVARDFPWTFTLSMLYIDNPVGTGFSFTDHFQGYA 177

  Fly   130 RNNRQIALDLVQLMKQFLTKYPDFRKVPLHIFSESYGGKMAPEFALELHLAKKVGELECDLKSVV 194
            .:...:|.||...:.||.|.:|::.|...::..|||.||..|..|..:|....|.:.:..||.:.
Mouse   178 TSEDDVAQDLYSALIQFFTLFPEYAKNDFYVTGESYAGKYVPALAHYIHSLNPVRKFKIRLKGIA 242

  Fly   195 VGNPWTSPLDSILSYAPFLLQSGIVDDDGYRRISRLAGELAALVYGGKWLRALMKATEVQDEI-- 257
            :|:.:|.|...|..||.||.:.|::|:...:...:...:....:...:|    |||.|:.|::
Mouse   243 IGDAYTDPESIIGGYAAFLYEIGLLDEQQQKYFQKQCSKCVKYIKEQEW----MKAFEILDKLLD 303

  Fly   258 -SASAGGVFIYNTQRRVHVDEVYRYGEDPQMSDFMR----SNVTKALGLGNMPVWMEQNSTVFER 317
             ..:.|..|..|.....:...:.:..|..:.|.|.:    ..|.:|:.:||..  ....:.|.:.
Mouse   304 GDVTTGSSFFQNVTGCTNYYNILQCTEPKEQSYFAKFLTLPQVRQAIHVGNQN--FSDGAEVEKH 366

  Fly   318 LSQDIFKPANQIVTKLLEETPIQVGIYSGILDLLCATPGTVNWIRRLKWRRSLEYAKAPRTAIRI 382
            |.:|..|.....:::::..  .:|.||:|.||::.|...|...:..:.|:.|..|.:|.|...:|
Mouse   367 LREDTVKSVKPWLSEIMNY--YKVLIYNGQLDIIVAAALTERSLMAMDWKGSRAYRRARRKVWKI 429

  Fly   383 ---EGMLEGYEKHGGKLSMFWVFRAGHLVQQENP 413
               :..:.||.:..||.....|...||::..:.|
Mouse   430 FKSDNEVAGYVRRVGKFHQVIVRGGGHILPYDQP 463

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31823	NP_723939.1	Peptidase_S10	26..425	CDD:298660	108/416 (26%)
Cpvl	XP_006506676.1	Peptidase_S10	78..474	CDD:366108	104/398 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2939
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S2918
OMA	1	1.010	-	-		QHG54069
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100109
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.670