DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31823 and scpep1

DIOPT Version :9

Sequence 1:	NP_723939.1	Gene:	CG31823 / 326163	FlyBaseID:	FBgn0051823	Length:	427	Species:	Drosophila melanogaster
Sequence 2:	NP_956486.1	Gene:	scpep1 / 393161	ZFINID:	ZDB-GENE-040426-890	Length:	445	Species:	Danio rerio

Alignment Length:	446	Identity:	140/446 - (31%)
Similarity:	236/446 - (52%)	Gaps:	52/446 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 RIWACALCFFL--------SLICVQGRVGLGPGVQEWDYVEVRKGAHLFYWLLYTTANVSHFIER 65
            |.|...|...|        |.:.||.:       :.|.||:||.|||:|:||.|..::.:.:.|.
Zfish     4 RSWIGMLVVLLFAVSFYEGSCVPVQAK-------ESWGYVDVRDGAHMFWWLYYANSSSASYKEL 61

  Fly    66 PLVIWLQGGPGVASTGSGIFEQLGPIDIEGKTRESSWLKHVNVLFVDSPVGTGFAYVEHHSLYAR 130
            |||:|||||||.:|.|.|.||::||:|.:.|.||:||::..:|||||:|||||::|.:......:
Zfish    62 PLVMWLQGGPGGSSCGFGNFEEIGPLDRDLKLRETSWVRAASVLFVDNPVGTGYSYTDTEDALTK 126

  Fly   131 NNRQIALDLVQLMKQFLTKYPDFRKVPLHIFSESYGGKMAPEFALELHLAKKVGELECDLKSVVV 195
            :...:|.|::.|:|:|.:...:|:.:|.:|||||||||||...:|||..|.:.|.::|:...|.:
Zfish   127 DVAMVASDMMVLLKKFFSLKTEFQSIPFYIFSESYGGKMAAAISLELTKAIQAGSIKCNFAGVAL 191

  Fly   196 GNPWTSPLDSILSYAPFLLQSGIVDDDGYRRISRLAGELAALVYGGKWLRALMKATEVQDEISAS 260
            |:.|.||:||::::..:|..:.::||.|...:...|..:...|..|.:|:|....:.:::.:..:
Zfish   192 GDSWISPIDSVMTWGAYLYSTSLLDDTGLNEVYTAAKAVMEAVQQGDYLKATDLWSMIENVVEQN 256

  Fly   261 AGGVFIYN--TQ---------------------RRVHVDEVYRYGEDPQMSDFMRSNVTKALGLG 302
            ..||..||  ||                     :|.|:..::|    ..:|:.|...:.:.||:
Zfish   257 TNGVNFYNILTQNSDEMVKSSADQAADGFLLALKRRHIRPLHR----QSLSELMNGPIRQKLGV- 316

  Fly   303 NMP---VWMEQNSTVFERLSQDIFKPANQIVTKLLEETPIQVGIYSGILDLLCATPGTVNWIRRL 364
             :|   .|..|...||..::.|..||...:|.:|| ...:.|.:|:|.|||:..|.|...|:::|
Zfish   317 -IPKNVTWGGQAEDVFVSMAGDFMKPVVDVVDQLL-AAGVNVTVYNGQLDLIVDTMGQEMWVKKL 379

  Fly   365 KWRRSLEYAKAPRTAI---RIEGMLEGYEKHGGKLSMFWVFRAGHLV-QQENPAAM 416
            ||.....:.|...||:   :.:.....:.|.....:.:|:.:|||:: ..:.|.|:
Zfish   380 KWDGLQNFNKLKWTALEDPQEQSQTGAFYKTYKNFAFYWILKAGHMIPSDQGPMAL 435

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31823	NP_723939.1	Peptidase_S10	26..425	CDD:298660	133/421 (32%)
scpep1	NP_956486.1	Peptidase_S10	26..439	CDD:298660	135/424 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592601
Domainoid	1	1.000	316	1.000	Domainoid score	I1245
eggNOG	1	0.900	-	-		E1_COG2939
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	317	1.000	Inparanoid score	I2521
OMA	1	1.010	-	-		QHG54069
OrthoDB	1	1.010	-	-		D274674at33208
OrthoFinder	1	1.000	-	-		FOG0003531
OrthoInspector	1	1.000	-	-		otm26594
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11802
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2409
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.870