DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31823 and cpy1

DIOPT Version :9

Sequence 1:	NP_723939.1	Gene:	CG31823 / 326163	FlyBaseID:	FBgn0051823	Length:	427	Species:	Drosophila melanogaster
Sequence 2:	NP_594425.1	Gene:	cpy1 / 2542465	PomBaseID:	SPAC19G12.10c	Length:	1002	Species:	Schizosaccharomyces pombe

Alignment Length:	458	Identity:	113/458 - (24%)
Similarity:	170/458 - (37%)	Gaps:	111/458 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 VGLGPGVQEWDYVEVRKGAHLFYWLLYTTANVSHFIERPLVIWLQGGPGVASTGSGIFEQLGPID 92
            :|:....|...|::|....|||:|...:..:..:   .|:|:||.||||.:|. :|:|.:|||..
pombe   581 LGIDTVKQYTGYLDVEDDRHLFFWFFESRNDPEN---DPVVLWLNGGPGCSSL-TGLFMELGPSS 641

  Fly    93 IEGKT-----RESSWLKHVNVLFVDSPVGTGFAYVEHHSLYARNNRQIALDLVQLMKQ------- 145
            |..:|     ...||..:.:|:|:|.|:.|||:          |.....||.|...|.
pombe   642 INIETLKPEYNPHSWNSNASVIFLDQPINTGFS----------NGDDSVLDTVTAGKDVYAFLNL 696

  Fly   146 FLTKYPDFRKVPLHIFSESYGGKMAPEFALELHLAKKVG---------ELE---CDLKSVVVGNP 198
            |..|:|.:..:..||..|||.|...|:||.|: :....|         |:|   .:||||::||.
pombe   697 FFAKFPQYAHLDFHIAGESYAGHYIPQFAKEI-MEHNQGANFFVASGYEMEKQYINLKSVLIGNG 760

  Fly   199 WTSPLDSILSYAPFLLQS---GIVDDDGYRRISRLAGELAALVYG-------------------- 240
            .|.||.....|.....:|   .|:..:...||:......|.|:.|
pombe   761 LTDPLVQYYFYGKMACESPYGPIMSQEECDRITGAYDTCAKLITGCYQTGFTPVCIGASLYCNNA 825

  Fly   241 --GKWLRALMKATEVQDEISASAGGVFIYNTQRRVHVDEVYRYGEDPQMSDFMRSN-VTKALGLG 302
              |.:.:.                |:.||:.:......|...|.|...:..::... |.:|||:.
pombe   826 MIGPFTKT----------------GLNIYDIREECRDQEHLCYPETGAIESYLNQEFVQEALGVE 874

  Fly   303 ------NMPV---------WMEQNSTVFERLSQDIFKPANQIVTKLLEETPIQVGIYSGILDLLC 352
                  |..|         ||.              |.....||.:| |..:.|.||:|..|.:|
pombe   875 YDYKGCNTEVNIGFLFKGDWMR--------------KTFRDDVTAIL-EAGLPVLIYAGDADYIC 924

  Fly   353 ATPGTVNWIRRLKWRRSLEYAKAPRTAIRIEGMLEGYEKHGGKLSMFWVFRAGHLVQQENPAAMA 417
            ...|...|...|:|....|:.:|........|...|..|.........::.|||:|....|.|..
pombe   925 NYMGNEAWTDALEWAGQREFYEAELKPWSPNGKEAGRGKSFKNFGYLRLYEAGHMVPFNQPEASL 989

  Fly   418 YIL 420
            .:|
pombe   990 EML 992

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31823	NP_723939.1	Peptidase_S10	26..425	CDD:298660	113/458 (25%)
cpy1	NP_594425.1	DUF4779	344..>419	CDD:292628
		Kex1	540..998	CDD:225490	113/458 (25%)
		Peptidase_S10	578..998	CDD:278857	113/458 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2939
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9280
orthoMCL	1	0.900	-	-		OOG6_100109
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.710