Protein Alignment CG31793 and Abcc3

DIOPT Version :10

• Sequence 1: NP_609930.4
• Gene: CG31793 / 326161
• FlyBaseID: FBgn0051793
• Length: 1307
• Species: Drosophila melanogaster
• Sequence 2: NP_001350116.1
• Gene: Abcc3 / 76408
• MGIID: 1923658
• Length: 1523
• Species: Mus musculus
• Alignment Length: 1368
• Identity: 472/1368 - (34%)
• Similarity: 736/1368 - (53%)
• Gaps: 135/1368 - (9%)

  Fly     8 PNPRESAGILSSLMFCFALPILFKGRKQTLQPTDLYKTLNEHEAASLGDEFFQGWEDEVARCRRK 72
            |.|..|||..|.|.|.:...:...|.::.|:..||:....|..:..:.....:.|:.:..:..|.
Mouse   206 PCPEASAGFFSRLSFWWFTRLAILGYRRPLEDRDLWSLSEEDCSHKVVQRLLEAWQKQQNQASRS 270

  Fly    73 ----------GD---------SGRKPSVLRVIGRVFGWRLIMSG-ITIAALELGTRATVPLLLAG 117
                      |:         ..::||.||.:.|.|...|:||. ..:....||  ...|.||:.
Mouse   271 QTATAEPKIPGEDAVLLKPRPKSKQPSFLRALVRTFTSSLLMSACFNLIQNLLG--FVNPQLLSI 333

  Fly   118 LISEFSEHGNGHSYNAQIYAVLLIACILASVLLTHPYMMGMMHLAMKMRVAVSSAIYRKALRLSR 182
            || .|.......::...:.|.|:........|:.|.|...:..:|:::|.|:...||||||.::.
Mouse   334 LI-RFISDPTAPTWWGFLLAGLMFLSSTMQTLILHQYYHCIFVMALRLRTAIIGVIYRKALVITN 397

  Fly   183 TSLGGTTTGQVVNLLSNDLNRFDRCLIHFHFLWLGPLELLIASYFLYEQIGMASFYGISILVLYL 247
            :....:|.|::|||:|.|..||.......:.||..||::::|.|||::.:|.::..|::::||.:
Mouse   398 SVKRESTVGEMVNLMSVDAQRFMDVSPFINLLWSAPLQVILAIYFLWQILGPSALAGVAVIVLLI 462

  Fly   248 PLQTYLSRVTSKLRLQTALRTDQRVRMMNEIISGIQVIKMYTWERPFGKLIGQMRRSEMSSIRQM 312
            ||...:|......:::.....|.|:::|:||::||:|:|:|.||..|.:.:..:|:||:..:|:.
Mouse   463 PLNGAVSMKMKTYQVKQMKFKDSRIKLMSEILNGIKVLKLYAWEPSFLEQVKGIRQSELQLLRKG 527

  Fly   313 NLLRG------ILLSFEITLGRIAIFVSLLGFVLGGGELTAERAFCVTAFYNILRRTVSKFFPSG 371
            ..|:.      |...|.:||..:.::|    :|.....|.||:||...:.:|||:..:: ..|..
Mouse   528 AYLQAISTFIWICTPFLVTLITLGVYV----YVDESNVLDAEKAFVSLSLFNILKIPLN-MLPQL 587

  Fly   372 MSQFAELLVSMRRITNFMMREEANVIDMSERRDEKAEEEQHLLKEVEKRSYPVGIGKEPDTLVEI 436
            :|...:..||::||.:|:.:.|.         |.:..|.:.:               .|...:.|
Mouse   588 ISGLTQASVSLKRIQDFLNQNEL---------DPQCVERKTI---------------SPGYAITI 628

  Fly   437 KALRARWGQEQHDL--VLNNVNMSLRRGQLVAVIGPVGSGKSSLIQAILGELPPESGSVQVSGKY 499
            ......|.|   ||  .|:::|:.:.:|.||||:||||.|||||:.|:|||:....|.|.|.|..
Mouse   629 HNGTFTWAQ---DLPPTLHSLNIQIPKGALVAVVGPVGCGKSSLVSALLGEMEKLEGVVSVKGSV 690

  Fly   500 SYASQEPWLFNASVRDNILFGLPMDKQRYRTVLKRCALERDLELL-HGDGTIVGERGASLSGGQR 563
            :|..|:.|:.|.::::|:|||.||:.:||:..|:.|||..||::| .||.|.:||:|.:||||||
Mouse   691 AYVPQQAWIQNCTLQENVLFGQPMNPKRYQQALETCALLADLDVLPGGDQTEIGEKGINLSGGQR 755

  Fly   564 ARICLARAVYRRADVYLLDDPLSAVDTHVGRHLFDECM--RGFLGKQLVILVTHQLQFLEDADLI 626
            .|:.||||||..|:::||||||||||:||.:|:||:.:  .|.|..:..:||||.:.||...|.|
Mouse   756 QRVSLARAVYSDANIFLLDDPLSAVDSHVAKHIFDQVIGPEGVLAGKTRVLVTHGISFLPQTDFI 820

  Fly   627 VIMDKGHVSACGTYEEMLKSGQDFAQLL-----------VESTQNSGGGDEIITSPNLS------ 674
            :::..|.||..|.|..:|:....||..|           .|:...:...:.::....||
Mouse   821 IVLAGGQVSEMGHYSALLQHDGSFANFLRNYAPDEDQEDHEAALQNANEEVLLLEDTLSTHTDLT 885

  Fly   675 --------------RQSSALSTK---------SSNGSSSSLESMVEKEKPKPSAVSSQESRSGGQ 716
                          |:.|:||::         ..:.:|...|::|.|.| :..|:..:|....|.
Mouse   886 DNEPAIYEVRKQFMREMSSLSSEGEVQNRTMPKKHTNSLEKEALVTKTK-ETGALIKEEIAETGN 949

  Fly   717 IGLSMYKKYFGAGCGVLVFVVLIMLCIGTQILASGGDYFLSYWVKNTA--------SSSTLDIYY 773
            :.||:|..| ....|:...:.:.:|..|....|.|.:.:||.| .|.|        :|..|.:|.
Mouse   950 VKLSVYWDY-AKSMGLCTTLSICLLYGGQSAAAIGANVWLSAW-SNDAEEHGQQNKTSVRLGVYA 1012

  Fly   774 FTAINVGLVICALLRTLLFFNITMHSSTELHNTMFQGLSRTALYFFHTNPSGRILNRFANDLGQV 838
            ...|..||::.....|::...|  .::..||..:.....|:...||.|.|||||||||:.|:..:
Mouse  1013 ALGILQGLLVMLSAFTMVVGAI--QAARLLHEALLHNKIRSPQSFFDTTPSGRILNRFSKDIYVI 1075

  Fly   839 DEVMPAVMLDCIQIFLTLTGIICVLCVTNPWYLINTFAMMLAFYYWRDFYLKTSRDVKRLEAVAR 903
            |||:...:|..:..|.|....|.|:..:.|.:::....:.:.:.:.:.||:.|||.:||||:::|
Mouse  1076 DEVLAPTILMLLNSFFTSISTIMVIVASTPLFMVVVLPLAVLYGFVQRFYVATSRQLKRLESISR 1140

  Fly   904 SPMYSHFSATLVGLPTIRAMGAQQTLIGQYDNYQDLHSSGYYTFVSTSRAFGYYLDLF--CV--- 963
            ||::||||.|:.|...|||.|..|......|...|.:....|.:::::|..|.:::..  ||
Mouse  1141 SPIFSHFSETVTGTSVIRAYGRIQDFKVLSDTKVDNNQKSSYPYIASNRWLGVHVEFVGNCVVLF 1205

  Fly   964 AYVISVILHNFFNPPLHNAGQIGLAITQALGMTGMVQWGMRQSAELENAMTSVERVLEYKDLDPE 1028
            |.:.:||..|..||     |.:||:::.||.:|..:.|.:|..::||:.:.:||||.||.....|
Mouse  1206 AALFAVIGRNSLNP-----GLVGLSVSYALQVTMALNWMIRMISDLESNIIAVERVKEYSKTKTE 1265

  Fly  1029 GDFNSPAEKQPPKSWPKEGKLVTKDLSLRYEPDTNSPCVLKGLSFTIQPMEKVGIVGRTGAGKSS 1093
            ..:...:.: .|:.||..|.:..::.|:||.|...  .|||.::..:|..|||||||||||||||
Mouse  1266 APWVVESNR-APEGWPTRGMVEFRNYSVRYRPGLE--LVLKNVTVHVQGGEKVGIVGRTGAGKSS 1327

  Fly  1094 LINALFR-LSYNDGAILIDSLDTNDIGLHDLRSKISIIPQEPVLFSGTMRYNLDPFEQYPDDKLW 1157
            :...||| |...:|.|:||.|:...||||||||:::||||:|:|||||:|.|||||.:|.::.:|
Mouse  1328 MTLCLFRILEAAEGEIVIDGLNVAHIGLHDLRSQLTIIPQDPILFSGTLRMNLDPFGRYSEEDIW 1392

  Fly  1158 KALEDVHLKEEISELPSGLQSIISEGGTNFSVGQRQLVCLARAILRENRILVMDEATANVDPQTD 1222
            :|||..||...:|..|:||....:|||.|.|||||||||||||:||::|:||:|||||.:|.:||
Mouse  1393 RALELSHLNTFVSSQPAGLDFQCAEGGDNLSVGQRQLVCLARALLRKSRVLVLDEATAAIDLETD 1457

  Fly  1223 ALIQATIRNKFKDCTVLTIAHRLNTIMDSDKVLVMDAGHVVEFGSPYELLTASKAKVFHGMVMQT 1287
            .|||.|||.:|:||||||||||||||||.::|||:|.|.|.||.||..|:.|  ..:|:||....
Mouse  1458 DLIQGTIRTQFEDCTVLTIAHRLNTIMDYNRVLVLDKGVVAEFDSPVNLIAA--GGIFYGMAKDA 1520

  Fly  1288 GKA 1290
            |.|
Mouse  1521 GLA 1523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31793	NP_609930.4	PLN03130	10..1305	CDD:215595	471/1366 (34%)
Abcc3	NP_001350116.1	MRP_assoc_pro	7..1522	CDD:188098	470/1365 (34%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	903..923		3/19 (16%)